[Term]
id: PR:000065785
name: circadian locomoter output cycles protein kaput phosphorylated 2 (human)
def: "A circadian locomoter output cycles protein kaput (human) that has been phosphorylated on the residues at the positions equivalent to Ser-440, Ser-441, Ser-446, Thr-451, and Thr-461 of the amino acid sequence represented by UniProtKB:O15516 and that includes at least one additional phosphorylated serine. UniProtKB:O15516, Ser-440/Ser-441/Ser-446, MOD:00046|Thr-451/Thr-461, MOD:00047|MOD:00046." [PRO:DNx, Reactome:R-HSA-9922270]
comment: Category=organism-modification.
synonym: "hCLOCK/Phos:2" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:O15516, Ser-440/Ser-441/Ser-446, MOD:00046|Thr-451/Thr-461, MOD:00047|MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
synonym: "p-S,T451,T461,S440,S441,S446-CLOCK" RELATED Reactome-displayName [PRO:DNx, Reactome:R-HSA-9922270]
xref: Reactome:R-HSA-9922270 "PR:000065785 located_in GO:0005654"
is_a: PR:O15516 ! circadian locomoter output cycles protein kaput (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: has_part MOD:00047 ! O-phospho-L-threonine