[Term]
id: PR:000063545
name: low-density lipoprotein receptor-related protein 6, signal peptide removed phosphoserine(2+) and phosphothreonine(2+) form (human)
def: "A low-density lipoprotein receptor-related protein 6 (human) that has had the signal peptide removed, that has been phosphorylated on the residue at the position equivalent to Ser-1490 of the amino acid sequence represented by UniProtKB:O75581, and that includes at least two additional phosphorylated serines and at least two phosphorylated threonines. UniProtKB:O75581, 20-1613, Ser-1490, MOD:00046|MOD:00046(2+)|MOD:00047(2+)." [PRO:DNx, Reactome:R-HSA-1458894]
comment: Category=organism-modification.
synonym: "hLRP6/SigPep-/Phos:4" EXACT PRO-short-label [PRO:DNx]
synonym: "p-2S,S1490,2T-LRP6" RELATED Reactome-displayName [PRO:DNx, Reactome:R-HSA-1458894]
synonym: "UniProtKB:O75581, 20-1613, Ser-1490, MOD:00046|MOD:00046(2+)|MOD:00047(2+)" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-1458894 "PR:000063545 located_in GO:0005886"
intersection_of: PR:O75581 ! low-density lipoprotein receptor-related protein 6 (human)
intersection_of: has_component MOD:00046 {minCardinality="2"} ! O-phospho-L-serine
intersection_of: has_component MOD:00047 {minCardinality="2"} ! O-phospho-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens