[Term]
id: PR:000061765
name: low-density lipoprotein receptor-related protein 6, signal peptide removed phosphoserine(5+) and phosphothreonine(5+) form (human)
def: "A low-density lipoprotein receptor-related protein 6 (human) that has had the signal peptide removed, that has been phosphorylated on the residues at the positions equivalent to Thr-1479, Ser-1490, and Thr-1493 of the amino acid sequence represented by UniProtKB:O75581, and that includes at least three additional phosphorylated threonines and at least four additional phosphorylated serines. UniProtKB:O75581, 20-1613, Thr-1479/Thr-1493, MOD:00047|Ser-1490, MOD:00046|MOD:00046(4+)|MOD:00047(3+)." [PRO:DNx, Reactome:R-HSA-1458895, Reactome:R-HSA-5368496]
comment: Category=organism-modification.
synonym: "hLRP6/SigPep-/Phos:3" EXACT PRO-short-label [PRO:DNx]
synonym: "p-4S,3T,T1479,S1490,T1493-LRP6" RELATED Reactome-displayName [PRO:DNx, Reactome:R-HSA-1458895, Reactome:R-HSA-5368496]
synonym: "UniProtKB:O75581, 20-1613, Thr-1479/Thr-1493, MOD:00047|Ser-1490, MOD:00046|MOD:00046(4+)|MOD:00047(3+)" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-1458895 "PR:000061765 located_in GO:0005886"
xref: Reactome:R-HSA-5368496 "PR:000061765 located_in GO:0031901"
intersection_of: PR:O75581 ! low-density lipoprotein receptor-related protein 6 (human)
intersection_of: has_component MOD:00046 {minCardinality="5"} ! O-phospho-L-serine
intersection_of: has_component MOD:00047 {minCardinality="5"} ! O-phospho-L-threonine
intersection_of: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens