[Term]
id: PR:000048143
name: kinase suppressor of Ras 1 phosphorylated 2 (human)
def: "A kinase suppressor of Ras 1 (human) that has been phosphorylated on the residue at the position equivalent to Ser-311, and phosphotyrosine at position 602 of the amino acid sequence represented by UniProtKB:Q8IVT5. UniProtKB:Q8IVT5, Ser-311, MOD:00046|Tyr-602, MOD:00048." [PRO:DAN, Reactome:R-HSA-5672656, Reactome:R-HSA-5672659]
comment: Category=organism-modification. Note: The modified site indicated here (Tyr-602) is referred to as Tyr-552 in some manuscripts. [PRO:DAN, PMID:23993095]
synonym: "hKSR1/Phos:2" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q8IVT5, Ser-311, MOD:00046|Tyr-602, MOD:00048" EXACT PRO-proteoform-std [PRO:DAN]
xref: Reactome:R-HSA-5672656 "PR:000048143 located_in GO:0005829"
xref: Reactome:R-HSA-5672659 "PR:000048143 located_in GO:0005886"
is_a: PR:Q8IVT5 ! kinase suppressor of Ras 1 (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens