[Term]
id: PR:000044833
name: pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial mature phosphorylated 5 (human)
def: "A pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial, transit peptide removed form (human) that has been phosphorylated on the residue equivalent to Ser-293, and that lacks phosphorylation on the residue at the position equivalent to Ser-300 of the amino acid sequence UniProtKB:P08559-1. Example: UniProtKB:P08559-1, 31-390, Ser-293, MOD:00046|Ser-300, PR:000026291." [PRO:AEL, CPTAC:breast_cancer_dataset]
comment: Category=organism-modification. Evidence=(ECO:0000006, for phosphorylation). Evidence=(ECO:0000001, based on PMID:23146587, for cleavage).
synonym: "hPDHA1/TransPep-/Phos:5" EXACT PRO-short-label [PRO:DAN]
synonym: "UniProtKB:P08559, 31-390, Ser-293, MOD:00046|Ser-300, PR:000026291" EXACT PRO-proteoform-std [PRO:DAN]
synonym: "PRO_0000020440, Ser-293, MOD:00046|Ser-300, PR:000026291" NARROW PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P08559-1, 31-390, Ser-293, MOD:00046|Ser-300, PR:000026291" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:000044835 ! pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial, transit peptide removed form (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens