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Protein Ontology report - roundabout homolog 3 (mouse)
PR:Q9Z2I4 - http://purl.obolibrary.org/obo/PR_Q9Z2I4
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza / GPI
  PRO ID
PR:Q9Z2I4   
  PRO nameroundabout homolog 3 (mouse) 
  Synonyms
PRO-Short-label: EXACT:mROBO3
Gene-based: RELATED:Rbig1 | Robo3
Other: EXACT:retinoblastoma-inhibiting gene 1 protein (mouse) | Rig-1 (mouse) | roundabout guidance receptor 3 (mouse)
  Definition"A roundabout homolog 3 that is encoded in the genome of mouse." [OMA:Q9Z2I4, PRO:DNx] 
  PRO Categoryorganism-gene 
  ParentPR:000014153 roundabout homolog 3
PR:000029032 Mus musculus protein
  Gene TemplateMGI:1343102 Robo3 (mouse)
  TaxonNCBITaxon:10090 Mus musculus
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene0                                                  Organism-Gene 1                                        
         Sequence0                                                  Organism-Sequence 6                                        
         Modification0                                                  Organism-Modification 0                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:Q9Z2I4
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

Comp. In Complex?
organism-gene


PR:Q9Z2I4 roundabout homolog 3 (mouse)
mROBO3

seqgroup


PR:000037775 roundabout homolog 3 isoform ROBO3A (mouse)
mROBO3/iso:ROBO3A[1/2]





PR:D3Z4M6 roundabout homolog 3 isoform ROBO3A.1 (mouse)





PR:Q9Z2I4-1 roundabout homolog 3 isoform ROBO3A.2 (mouse)

seqgroup


PR:000037777 roundabout homolog 3 isoform ROBO3.1 (mouse)
mROBO3/iso:ROBO3[A/B]1
Yes




PR:D3Z4M6 roundabout homolog 3 isoform ROBO3A.1 (mouse)





PR:E9QPQ1 roundabout homolog 3 isoform ROBO3B.1 (mouse)

seqgroup


PR:000037778 roundabout homolog 3 isoform ROBO3.2 (mouse)
mROBO3/iso:ROBO3[A/B]2
Yes




PR:Q9Z2I4-1 roundabout homolog 3 isoform ROBO3A.2 (mouse)





PR:Q9Z2I4-2 roundabout homolog 3 isoform ROBO3B.2 (mouse)

seqgroup


PR:000037776 roundabout homolog 3 isoform ROBO3B (mouse)
mROBO3/iso:ROBO3B[1/2]





PR:E9QPQ1 roundabout homolog 3 isoform ROBO3B.1 (mouse)





PR:Q9Z2I4-2 roundabout homolog 3 isoform ROBO3B.2 (mouse)

organism-sequence


PR:D3Z4M6 roundabout homolog 3 isoform ROBO3A.1 (mouse)
mROBO3/iso:ROBO3A1
Yes
organism-sequence


PR:E9QPQ1 roundabout homolog 3 isoform ROBO3B.1 (mouse)
mROBO3/iso:B1

organism-sequence


PR:Q9Z2I4-1 roundabout homolog 3 isoform ROBO3A.2 (mouse)
mROBO3/iso:ROBO3A.2

organism-sequence


PR:Q9Z2I4-2 roundabout homolog 3 isoform ROBO3B.2 (mouse)
mROBO3/iso:ROBO3B.2

organism-sequence


PR:Q9Z2I4-3 roundabout homolog 3 isoform m1 (mouse)
mROBO3/iso:m1

organism-sequence


PR:Q9Z2I4-4 roundabout homolog 3 isoform m3 (mouse)
mROBO3/iso:m3

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000037777 mROBO3/iso:ROBO3[A/B]1
The resulting 78 amino acid peptide is highly enriched in arginine/serine dipeptide repeats		 acts_upstream_of_or_withinGO:0061642 chemoattraction of axon MGI_ref:3834283; PMID:18466743
located_inGO:0030424 axon MGI_ref:3834283; PMID:18466743
PR:000037778 mROBO3/iso:ROBO3[A/B]2 acts_upstream_of_or_withinGO:0061643 chemorepulsion of axon MGI_ref:3834283; PMID:18466743
located_inGO:0030424 axon MGI_ref:3834283; PMID:18466743
PR:D3Z4M6 mROBO3/iso:ROBO3A1
This isoform has a longer N-terminal sequence in comparison with ROBO3B isoforms and the C-terminal sequence arises from splicing of exon 26 to exon 27 and then to exon 28, with the resulting 78 amino acid peptide highly enriched in arginine/serine dipeptide repeats		 acts_upstream_of_or_withinGO:0016199 axon midline choice point recognition MGI_ref:3834283; PMID:18466743
GO:0061642 chemoattraction of axon MGI_ref:3834283; PMID:18466743
GO:0071679 commissural neuron axon guidance MGI_ref:3834283; PMID:18466743