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Protein Ontology report - potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (human)
PR:Q9Y3Q4 - http://purl.obolibrary.org/obo/PR_Q9Y3Q4
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza / PAF / GPI
  PRO ID
PR:Q9Y3Q4   
  PRO namepotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (human) 
  Synonyms
PRO-Short-label: EXACT:hHCN4
Gene-based: RELATED:HCN4
  Definition"A potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 that is encoded in the genome of human." [PRO:CNA, UniProtKB:Q9Y3Q4] 
  PRO Categoryorganism-gene 
  ParentPR:000000708 potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4
PR:000029067 Homo sapiens protein
  Gene TemplateHGNC:16882 HCN4 (human)
  TaxonNCBITaxon:9606 Homo sapiens
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene0                                                  Organism-Gene 1                                        
         Sequence0                                                  Organism-Sequence 3                                        
         Modification0                                                  Organism-Modification 0                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:Q9Y3Q4
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

Comp. In Complex?
organism-gene


PR:Q9Y3Q4 potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (human)
hHCN4

organism-sequence


PR:000000759 potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 sequence variant D553N (human)
hHCN4/var:D553N
Yes
organism-sequence


PR:000000760 potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 sequence variant S672R (human)
hHCN4/var:S672R
Yes
organism-sequence


PR:Q9Y3Q4-1 potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 isoform 1 (human)
hHCN4/iso:1
Yes
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Functional Annotation (GO-centric view) Switch to PRO Centric View     

Biological Process GO Term
Protein Forms & Complexes
Evidence
GO:0006812 monoatomic cation transportPR:Q9Y3Q4-1 hHCN4/iso:1 PMID:10228147
GO:0006936 muscle contractionPR:Q9Y3Q4-1 hHCN4/iso:1 PMID:10228147

Disease Associated GO Term
Protein Forms & Complexes
Evidence
DO:13884 sick sinus syndromePR:000000759 hHCN4/var:D553N PMID:15123648
PR:000000760 hHCN4/var:S672R PMID:16407510

Molecular Function GO Term
Protein Forms & Complexes
Evidence
GO:0005222 intracellularly cAMP-activated cation channel activityPR:000000760 hHCN4/var:S672R PMID:16407510
GO:0005261 monoatomic cation channel activityPR:Q9Y3Q4-1 hHCN4/iso:1 PMID:10228147
GO:0022843 voltage-gated monoatomic cation channel activityPR:000000760 hHCN4/var:S672R PMID:16407510

Cellular Location GO Term
Protein Forms & Complexes
Evidence
NOT GO:0005886 plasma membranePR:000000759 hHCN4/var:D553N PMID:15123648