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Protein Ontology report - serine/threonine-protein kinase STK11 isoform 1 (mouse)
PR:Q9WTK7-1 - http://purl.obolibrary.org/obo/PR_Q9WTK7-1
 
  Protein Forms  Complex  Annotations      
Ontology Information Show OBO stanza / PAF / GPI
  PRO ID
PR:Q9WTK7-1   
  PRO nameserine/threonine-protein kinase STK11 isoform 1 (mouse) 
  Synonyms
PRO-Short-label: EXACT:mSTK11/iso:1
Other: EXACT:mLKB1(L) | mLKB1L
  Definition"A serine/threonine-protein kinase STK11 isoform 1 that is encoded in the genome of mouse. This isoform includes the sequence encoded by exon IXa. This isoform is widely expressed." [PRO:KRC] 
  CommentEvidence=Detected by Western blot in all tissues tested (testis, liver, heart, brain, kidney, lung, muscle). 
  PRO Categoryorganism-sequence 
  ParentPR:000036874 serine/threonine-protein kinase STK11 isoform 1
PR:Q9WTK7 serine/threonine-protein kinase STK11 (mouse)
  TaxonNCBITaxon:10090 Mus musculus
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Sequence0                                                  Organism-Sequence 1                                        
         Modification0                                                  Organism-Modification 5                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:Q9WTK7-1
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

Comp. In Complex?
organism-sequence


PR:Q9WTK7-1 serine/threonine-protein kinase STK11 isoform 1 (mouse)
mSTK11/iso:1
Yes
Yes
organism-modification


PR:000036893 serine/threonine-protein kinase STK11 isoform 1 phosphorylated 1 (mouse)
mSTK11/iso:1/Phos:1
Yes
organism-modification


PR:000036995 serine/threonine-protein kinase STK11 isoform 1 phosphorylated 2 (mouse)
mSTK11/iso:1/Phos:2
Yes
organism-modification


PR:000036997 serine/threonine-protein kinase STK11 isoform 1 unphosphorylated 1 (mouse)
mSTK11/iso:1/UnPhos:1
Yes
organism-modification


PR:000045394 serine/threonine-protein kinase STK11 isoform 1 farnesylated 1 (mouse)
mSTK11/iso:1/Farn:1

organism-modification


PR:000045395 serine/threonine-protein kinase STK11 isoform 1 farnesylated and phosphorylated 1 (mouse)
mSTK11/iso:1/FarnPhos:1

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mSTK11/iso:1 forms found in complexes   

mSTK11/iso:1 Component
 Complexes
PR:Q9WTK7ZDASHZ1 mSTK11/iso:1 PR:000025037 Stk11 isoform 1:Strada:Cab39 heterotrimer (mouse)
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Functional Annotation (GO-centric view) Switch to PRO Centric View     

Biological Process GO Term
Protein Forms & Complexes
Evidence
GO:0032147 activation of protein kinase activityPR:Q9WTK7-1 mSTK11/iso:1 MGI_ref:3836081; PMID:18854309
GO:0036399 TCR signalosome assemblyPR:000036995 mSTK11/iso:1/Phos:2 MGI_ref:5003385; PMID:21487392
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylationPR:000036995 mSTK11/iso:1/Phos:2 MGI_ref:5003385; PMID:21487392

Cellular Location GO Term
Protein Forms & Complexes
Evidence
GO:0005634 nucleusPR:000036893 mSTK11/iso:1/Phos:1 MGI_ref:4439241; PMID:20142099
GO:0005737 cytoplasmPR:000036997 mSTK11/iso:1/UnPhos:1 MGI_ref:4439241; PMID:20142099
PR:Q9WTK7-1 mSTK11/iso:1 MGI_ref:3836081; PMID:18854309
GO:0016020 membranePR:Q9WTK7-1 mSTK11/iso:1 MGI_ref:3836081; PMID:18854309
GO:0036398 TCR signalosomePR:000036995 mSTK11/iso:1/Phos:2 MGI_ref:5003385; PMID:21487392