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Protein Ontology report - double-stranded RNA-specific adenosine deaminase (mouse)
PR:Q99MU3 - http://purl.obolibrary.org/obo/PR_Q99MU3
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza / PAF / GPI
  PRO ID
PR:Q99MU3   
  PRO namedouble-stranded RNA-specific adenosine deaminase (mouse) 
  Synonyms
PRO-Short-label: EXACT:mADAR
Gene-based: RELATED:Adar
Other: EXACT:DRADA (mouse) | RNA adenosine deaminase 1 (mouse)
  Definition"A double-stranded RNA-specific adenosine deaminase that is encoded in the genome of mouse." [OMA:Q99MU3, PRO:DNx] 
  PRO Categoryorganism-gene 
  ParentPR:000003745 double-stranded RNA-specific adenosine deaminase
PR:000029032 Mus musculus protein
  Gene TemplateMGI:1889575 Adar (mouse)
  TaxonNCBITaxon:10090 Mus musculus
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene0                                                  Organism-Gene 1                                        
         Sequence0                                                  Organism-Sequence 5                                        
         Modification0                                                  Organism-Modification 0                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:Q99MU3
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

Comp. In Complex?
organism-gene


PR:Q99MU3
double-stranded RNA-specific adenosine deaminase (mouse)
mADAR
"A double-stranded RNA-specific adenosine deaminase that is encoded in the genome of mouse." [OMA:Q99MU3, PRO:DNx]

organism-sequence


PR:Q99MU3-1
double-stranded RNA-specific adenosine deaminase isoform 1 (mouse)
mADAR/iso:1
"A double-stranded RNA-specific adenosine deaminase isoform 1 that is encoded in the genome of mouse." [PMID:12954622, PRO:HJD]
Yes
organism-sequence


PR:Q99MU3-2
double-stranded RNA-specific adenosine deaminase isoform 2 (mouse)
mADAR/iso:2
"A double-stranded RNA-specific adenosine deaminase isoform 2 that is encoded in the genome of mouse. This form is produced by alternative splicing of isoform 1." [PMID:12954622, PRO:HJD]
Yes
organism-sequence


PR:Q99MU3-3
double-stranded RNA-specific adenosine deaminase isoform 3 (mouse)
mADAR/iso:3
"A double-stranded RNA-specific adenosine deaminase isoform 3 that is encoded in the genome of mouse. This form is produced by alternative splicing of isoform 1." [PMID:12954622, PRO:HJD]
Yes
organism-sequence


PR:Q99MU3-4
double-stranded RNA-specific adenosine deaminase isoform 4 (mouse)
mADAR/iso:4
"A double-stranded RNA-specific adenosine deaminase isoform 4 that is encoded in the genome of mouse. Produced by alternative splicing of isoform 1." [PMID:12954622, PRO:HJD]
Yes
organism-sequence


PR:Q99MU3-5
double-stranded RNA-specific adenosine deaminase isoform 5 (mouse)
mADAR/iso:5
"A double-stranded RNA-specific adenosine deaminase isoform 5 that is encoded in the genome of mouse." [PRO:CNA]

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Functional Annotation (GO-centric view) Switch to PRO Centric View     

Biological Process GO Term
Protein Forms & Complexes
Evidence
GO:0001701 in utero embryonic developmentPR:Q99MU3-1 mADAR/iso:1 MGI_ref:4939544; PMID:21173229
GO:0045071 negative regulation of viral genome replicationPR:Q99MU3-1 mADAR/iso:1 MGI_ref:4939544; PMID:21173229
GO:0051607 defense response to virusPR:Q99MU3-1 mADAR/iso:1 MGI_ref:4939544; PMID:21173229

Molecular Function GO Term
Protein Forms & Complexes
Evidence
GO:0003726 double-stranded RNA adenosine deaminase activityPR:Q99MU3-1 mADAR/iso:1 MGI_ref:5515381; PMID:12954622
PR:Q99MU3-2 mADAR/iso:2 MGI_ref:5515381; PMID:12954622
PR:Q99MU3-3 mADAR/iso:3 MGI_ref:5515381; PMID:12954622
PR:Q99MU3-4 mADAR/iso:4 MGI_ref:5515381; PMID:12954622

Cellular Location GO Term
Protein Forms & Complexes
Evidence
GO:0005730 nucleolusPR:Q99MU3-3 mADAR/iso:3 MGI_ref:5515381; PMID:12954622
GO:0005737 cytoplasmPR:Q99MU3-1 mADAR/iso:1 MGI_ref:5515381; PMID:12954622
PR:Q99MU3-2 mADAR/iso:2 MGI_ref:5515381; PMID:12954622