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Protein Ontology report - protein smoothened (human)
PR:Q99835 - http://purl.obolibrary.org/obo/PR_Q99835
 
  Protein Forms      
Ontology Information Show OBO stanza / GPI
  PRO ID
PR:Q99835   
  PRO nameprotein smoothened (human) 
  Synonyms
PRO-Short-label: EXACT:hSMO
Gene-based: RELATED:SMO | SMOH
Other: EXACT:protein Gx (human)
  Definition"A protein smoothened that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q99835
  PRO Categoryorganism-gene 
  ParentPR:000015288 protein smoothened
PR:000029067 Homo sapiens protein
  Gene TemplateHGNC:11119 SMO (human)
  TaxonNCBITaxon:9606 Homo sapiens
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene0                                                  Organism-Gene 1                                        
         Sequence0                                                  Organism-Sequence 0                                        
         Modification0                                                  Organism-Modification 6                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:Q99835
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
organism-gene



PR:Q99835

protein smoothened (human)

hSMO


"A protein smoothened that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q99835]


organism-modification



PR:000049297

protein smoothened, signal peptide removed form (human)

hSMO/SigPep-


"A protein smoothened (human) that has had the signal peptide removed. UniProtKB:Q99835, 28-787." [PRO:DNx, Reactome:R-HSA-445121, Reactome:R-HSA-5610419, Reactome:R-HSA-5610422, Reactome:R-HSA-5624094]


organism-modification



PR:000049298

protein smoothened, signal peptide removed phosphorylated 1 (human)

hSMO/SigPep-/Phos:1


"A protein smoothened (human) that has had the signal peptide removed and has been post-translationally modified to include phosphoserine at positions 588, 590 and 595, and phosphothreonine at position 593 of the amino acid sequence represented by UniProtKB:Q99835. UniProtKB:Q99835, 28-787, Ser-588/Ser-590/Ser-595, MOD:00046|Thr-593, MOD:00047." [PRO:DNx, Reactome:R-HSA-5632525]


organism-modification



PR:000049299

protein smoothened, signal peptide removed phosphorylated 2 (human)

hSMO/SigPep-/Phos:2


"A protein smoothened (human) that has had the signal peptide removed and has been post-translationally modified to include phosphoserine at positions 588, 590, 595, 611, 615 and 616, and phosphothreonine at position 593 of the amino acid sequence represented by UniProtKB:Q99835. UniProtKB:Q99835, 28-787, Ser-588/Ser-590/Ser-595/Ser-611/Ser-615/Ser-616, MOD:00046|Thr-593, MOD:00047." [PRO:DNx, Reactome:R-HSA-5632528]


organism-modification



PR:000057979

protein smoothened N-glycosylated 1 (human)

hSMO/NGlyco:1


"A protein smoothened (human) that has been N-glycosylated at the residue equivalent to Asn-35 of the amino acid sequence represented by UniProtKB:Q99835-1, in which the glycan composition is represented by GlyTouCan:G08293MJ. Example: UniProtKB:Q99835-1, Asn-35, MOD:00160~GNO:G08293MJ." [GlyGen:Q99835-1, PMID:29671580, PRO:DNx]


organism-modification



PR:000057980

protein smoothened O-glycosylated 1 (human)

hSMO/OGlyco:1


"A protein smoothened (human) that has been O-glycosylated at the residue equivalent to Thr-500 of the amino acid sequence represented by UniProtKB:Q99835-1, in which the glycan composition is represented by GlyTouCan:G29068FM. Example: UniProtKB:Q99835-1, Thr-500, MOD:00005~GNO:G29068FM." [GlyGen:Q99835-1, PMID:30459171, PRO:DNx]


organism-modification



PR:000057981

protein smoothened O-glycosylated 2 (human)

hSMO/OGlyco:2


"A protein smoothened (human) that has been O-glycosylated at the residue equivalent to Thr-55 of the amino acid sequence represented by UniProtKB:Q99835-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:Q99835-1, Thr-55, MOD:00005~GNO:G43417UB." [GlyGen:Q99835-1, PMID:30459171, PRO:DNx]