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Protein Ontology report - histone-lysine N-methyltransferase, H3 lysine-79 specific (human)
PR:Q8TEK3 - http://purl.obolibrary.org/obo/PR_Q8TEK3
 
  Protein Forms      
Ontology Information Show OBO stanza / GPI
  PRO ID
PR:Q8TEK3   
  PRO namehistone-lysine N-methyltransferase, H3 lysine-79 specific (human) 
  Synonyms
PRO-Short-label: EXACT:hDOT1L
Gene-based: RELATED:DOT1L | KIAA1814 | KMT4
Other: EXACT:DOT1-like protein (human) | H3-K79-HMTase (human) | histone H3-K79 methyltransferase (human) | lysine N-methyltransferase 4 (human)
  Definition"A histone-lysine N-methyltransferase, H3 lysine-79 specific that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q8TEK3] 
  PRO Categoryorganism-gene 
  ParentPR:000006642 histone-lysine N-methyltransferase, H3 lysine-79 specific
PR:000029067 Homo sapiens protein
  Gene TemplateHGNC:24948 DOT1L (human)
  TaxonNCBITaxon:9606 Homo sapiens
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene0                                                  Organism-Gene 1                                        
         Sequence0                                                  Organism-Sequence 2                                        
         Modification0                                                  Organism-Modification 7                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:Q8TEK3
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

Comp. In Complex?
organism-gene


PR:Q8TEK3
histone-lysine N-methyltransferase, H3 lysine-79 specific (human)
hDOT1L
"A histone-lysine N-methyltransferase, H3 lysine-79 specific that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q8TEK3]

organism-sequence


PR:Q8TEK3-1
histone-lysine N-methyltransferase, H3 lysine-79 specific isoform h2 (human)
hDOT1L/iso:h2
"A histone-lysine N-methyltransferase, H3 lysine-79 specific (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8TEK3-1." [PRO:DNx, UniProtKB:Q8TEK3]

organism-sequence


PR:Q8TEK3-2
histone-lysine N-methyltransferase, H3 lysine-79 specific isoform h1 (human)
hDOT1L/iso:h1
"A histone-lysine N-methyltransferase, H3 lysine-79 specific (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8TEK3-2." [PRO:DNx, UniProtKB:Q8TEK3]

organism-modification


PR:000065787
histone-lysine N-methyltransferase, H3 lysine-79 specific phosphorylated 1 (human)
hDOT1L/Phos:1
"A histone-lysine N-methyltransferase, H3 lysine-79 specific (human) that has been phosphorylated on the residue at the position equivalent to Thr-772 of the amino acid sequence represented by UniProtKB:Q8TEK3-2. Example: UniProtKB:Q8TEK3-2, Thr-772, MOD:00047." [IEDB_epitope:1373793, PRO:DNx]

organism-modification


PR:000066809
histone-lysine N-methyltransferase, H3 lysine-79 specific deaminated 1 (human)
hDOT1L/Deam:1
"A histone-lysine N-methyltransferase, H3 lysine-79 specific (human) that has been deaminated on the residue at the position equivalent to Gln-1482 of the amino acid sequence represented by UniProtKB:Q8TEK3-2. Example: UniProtKB:Q8TEK3-2, Gln-1482, MOD:00685." [IEDB_epitope:1364601, PRO:DNx]

organism-modification


PR:000069744
histone-lysine N-methyltransferase, H3 lysine-79 specific phosphorylated 2 (human)
hDOT1L/Phos:2
"A histone-lysine N-methyltransferase, H3 lysine-79 specific (human) that has been phosphorylated on the residue at the position equivalent to Thr-957 of the amino acid sequence represented by UniProtKB:Q8TEK3-2. Example: UniProtKB:Q8TEK3-2, Thr-957, MOD:00047." [IEDB_epitope:2149061, PRO:DNx]

organism-modification


PR:000071351
histone-lysine N-methyltransferase, H3 lysine-79 specific phosphorylated 3 (human)
hDOT1L/Phos:3
"A histone-lysine N-methyltransferase, H3 lysine-79 specific (human) that has been phosphorylated on the residue at the position equivalent to Thr-1148 of the amino acid sequence represented by UniProtKB:Q8TEK3-2. Example: UniProtKB:Q8TEK3-2, Thr-1148, MOD:00047." [IEDB_epitope:1372607, PRO:DNx]

organism-modification


PR:000072324
histone-lysine N-methyltransferase, H3 lysine-79 specific phosphorylated 4 (human)
hDOT1L/Phos:4
"A histone-lysine N-methyltransferase, H3 lysine-79 specific (human) that has been phosphorylated on the residue at the position equivalent to Ser-1001 of the amino acid sequence represented by UniProtKB:Q8TEK3-2. Example: UniProtKB:Q8TEK3-2, Ser-1001, MOD:00046." [IEDB_epitope:609924, PRO:DNx]

organism-modification


PR:000080968
histone-lysine N-methyltransferase, H3 lysine-79 specific deaminated 2 (human)
hDOT1L/Deam:2
"A histone-lysine N-methyltransferase, H3 lysine-79 specific (human) that has been deaminated on the residue at the position equivalent to Gln-651 of the amino acid sequence represented by UniProtKB:Q8TEK3-2. Example: UniProtKB:Q8TEK3-2, Gln-651, MOD:00685." [IEDB_epitope:1977344, PRO:DNx]

organism-modification


PR:000083413
histone-lysine N-methyltransferase, H3 lysine-79 specific deaminated 3 (human)
hDOT1L/Deam:3
"A histone-lysine N-methyltransferase, H3 lysine-79 specific (human) that has been deaminated on the residue at the position equivalent to Asn-810 of the amino acid sequence represented by UniProtKB:Q8TEK3-2. Example: UniProtKB:Q8TEK3-2, Asn-810, MOD:00684." [IEDB_epitope:1574052, PRO:DNx]