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Protein Ontology report - outer kinetochore KNL1 complex subunit KNL1 (human)
PR:Q8NG31 - http://purl.obolibrary.org/obo/PR_Q8NG31
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza / PAF / GPI
  PRO ID
PR:Q8NG31   
  PRO nameouter kinetochore KNL1 complex subunit KNL1 (human) 
  Synonyms
PRO-Short-label: EXACT:hKNL1
Gene-based: RELATED:CASC5 | KIAA1570 | KNL1
Other: EXACT:AF15q14 (human) | ALL1-fused gene from chromosome 15q14 protein (human) | blinkin (human) | Bub-linking kinetochore protein (human) | cancer susceptibility candidate gene 5 protein (human) | cancer/testis antigen 29 (human) | CT29 (human) | kinetochore scaffold 1 (human) | kinetochore-null protein 1 (human) | protein CASC5 (human) | protein D40/AF15q14 (human)
  Definition"An outer kinetochore KNL1 complex subunit KNL1 that is encoded in the genome of human." [PMID:20624902, PRO:KER] 
  PRO Categoryorganism-gene 
  ParentPR:000005050 outer kinetochore KNL1 complex subunit KNL1
PR:000029067 Homo sapiens protein
  Gene TemplateHGNC:24054 KNL1 (human)
  TaxonNCBITaxon:9606 Homo sapiens
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene0                                                  Organism-Gene 1                                        
         Sequence0                                                  Organism-Sequence 4                                        
         Modification0                                                  Organism-Modification 6                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:Q8NG31
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
organism-gene



PR:Q8NG31

outer kinetochore KNL1 complex subunit KNL1 (human)

hKNL1


"An outer kinetochore KNL1 complex subunit KNL1 that is encoded in the genome of human." [PMID:20624902, PRO:KER]

Yes

organism-sequence



PR:Q8NG31-1

outer kinetochore KNL1 complex subunit KNL1 isoform 1 (human)

hKNL1/iso:1


"An outer kinetochore KNL1 complex subunit KNL1 isoform 1 that is encoded in the genome of human." [PRO:CNA]


organism-sequence



PR:Q8NG31-2

outer kinetochore KNL1 complex subunit KNL1 isoform 2 (human)

hKNL1/iso:2


"An outer kinetochore KNL1 complex subunit KNL1 isoform 2 that is encoded in the genome of human." [PRO:CNA]


organism-modification



PR:000035558

outer kinetochore KNL1 complex subunit KNL1 isoform 2 phosphorylated 1 (human)

hKNL1/iso:2/Phos:1


"An outer kinetochore KNL1 complex subunit KNL1 isoform 2 phosphorylated 1 in human. UniProtKB:Q8NG31-2, Thr-875/Thr-1075/Thr-1089/Thr-1129/Thr-1154/Thr-1167, MOD:00047|Ser-1022/Ser-1037, MOD:00046." [PMID:22660415, PRO:KER]

Yes

organism-modification



PR:000035560

outer kinetochore KNL1 complex subunit KNL1 isoform 2 unphosphorylated form (human)

hKNL1/iso:2/PhosRes-


"An outer kinetochore KNL1 complex subunit KNL1 isoform 2 unphosphorylated form in human." [PRO:KER]


organism-sequence



PR:Q8NG31-3

outer kinetochore KNL1 complex subunit KNL1 isoform h3 (human)

hKNL1/iso:h3


"An outer kinetochore KNL1 complex subunit KNL1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8NG31-3." [PRO:DNx, UniProtKB:Q8NG31]


organism-sequence



PR:Q8NG31-4

outer kinetochore KNL1 complex subunit KNL1 isoform h4 (human)

hKNL1/iso:h4


"An outer kinetochore KNL1 complex subunit KNL1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8NG31-4." [PRO:DNx, UniProtKB:Q8NG31]


organism-modification



PR:000071007

outer kinetochore KNL1 complex subunit KNL1 methylated 1 (human)

hKNL1/Me:1


"An outer kinetochore KNL1 complex subunit KNL1 (human) that has been methylated on the residue at the position equivalent to Cys-130 of the amino acid sequence represented by UniProtKB:Q8NG31-1. Example: UniProtKB:Q8NG31-1, Cys-130, MOD:00660." [IEDB_epitope:1036496, PRO:DNx]


organism-modification



PR:000071490

outer kinetochore KNL1 complex subunit KNL1 cysteinylated 1 (human)

hKNL1/Cyst:1


"An outer kinetochore KNL1 complex subunit KNL1 (human) that has been cysteinylated on the residue at the position equivalent to Cys-2338 of the amino acid sequence represented by UniProtKB:Q8NG31-1. Example: UniProtKB:Q8NG31-1, Cys-2338, MOD:00765." [IEDB_epitope:1564396, PRO:DNx]


organism-modification



PR:000077771

outer kinetochore KNL1 complex subunit KNL1 phosphorylated 1 (human)

hKNL1/Phos:1


"An outer kinetochore KNL1 complex subunit KNL1 (human) that has been phosphorylated on the residue at the position equivalent to Ser-1773 of the amino acid sequence represented by UniProtKB:Q8NG31-1. Example: UniProtKB:Q8NG31-1, Ser-1773, MOD:00046." [IEDB_epitope:609244, PRO:DNx]


organism-modification



PR:000083702

outer kinetochore KNL1 complex subunit KNL1 deaminated 1 (human)

hKNL1/Deam:1


"An outer kinetochore KNL1 complex subunit KNL1 (human) that has been deaminated on the residue at the position equivalent to Asn-1514 of the amino acid sequence represented by UniProtKB:Q8NG31-1. Example: UniProtKB:Q8NG31-1, Asn-1514, MOD:00684." [IEDB_epitope:1365942, PRO:DNx]


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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000035558 hKNL1/iso:2/Phos:1
UniProtKB:Q8NG31-2, Thr-875/Thr-1075/Thr-1089/Thr-1129/Thr-1154/Thr-1167, MOD:00047|Ser-1022/Ser-1037, MOD:00046
acts_upstream_of_or_withinincreased GO:0034501 protein localization to kinetochore relative to PR:000035560 hKNL1/iso:2/PhosRes- PMID:22660415
PR:Q8NG31 hKNL1 enablesGO:0005515 protein binding with PR:O14777 HEC BioGRID:BG-697221
GO:0005515 protein binding with PR:O43683 BUB1 BioGRID:BG-697221
GO:0005515 protein binding with PR:O60566 BUB1B BioGRID:BG-697221
located_inGO:0000776 kinetochore PMID:20624902