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Protein Ontology report - Bcl2-associated agonist of cell death isoform 1 (mouse)

PR:Q61337-1 - http://purl.obolibrary.org/obo/PR_Q61337-1

Protein Forms

Annotations

Ontology Information

Show OBO stanza

GPI

PRO ID

PR:Q61337-1

PRO name

Bcl2-associated agonist of cell death isoform 1 (mouse)

Synonyms

PRO-Short-label:

EXACT:

mBAD/iso:1

Definition

"A Bcl2-associated agonist of cell death isoform 1 that is encoded in the genome of mouse." [PRO:JAN]

PRO Category

organism-sequence

Parent

PR:000002280 Bcl2-associated agonist of cell death isoform 1
PR:Q61337 Bcl2-associated agonist of cell death (mouse)

Taxon

NCBITaxon:10090 Mus musculus

Terms by PRO Category

Organism-Independent		Organism-Specific
Category	Number of Terms	Category	Number of Terms
Sequence	0	Organism-Sequence	1
Modification	0	Organism-Modification	9

Term Hierarchy
Visualization

DAG:

OLS:

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Related Cross References
Db identifiers	UniProtKB:Q61337-1

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Protein Forms

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Category

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?

organism-sequence

PR:Q61337-1

Bcl2-associated agonist of cell death isoform 1 (mouse)

mBAD/iso:1

"A Bcl2-associated agonist of cell death isoform 1 that is encoded in the genome of mouse." [PRO:JAN]

organism-modification

PR:000026133

Bcl2-associated agonist of cell death isoform 1 phosphorylated 2 (mouse)

mBAD/iso:1/Phos:2

"A Bcl2-associated agonist of cell death isoform 1 phosphorylated 2 in mouse. UniProtKB:Q61337-1, Ser-112/Ser-136/Ser-155, MOD:00046." [PMID:10880354, PMID:10949026, PRO:JAN]

Yes

organism-modification

PR:000026135

Bcl2-associated agonist of cell death isoform 1 phosphorylated 4 (mouse)

mBAD/iso:1/Phos:4

"A Bcl2-associated agonist of cell death isoform 1 phosphorylated 4 in mouse. UniProtKB:Q61337-1, Thr-201, MOD:00047." [PMID:14967141, PRO:JAN]

Yes

organism-modification

PR:000026136

Bcl2-associated agonist of cell death isoform 1 phosphorylated 5 (mouse)

mBAD/iso:1/Phos:5

"A Bcl2-associated agonist of cell death isoform 1 phosphorylated 5 in mouse. UniProtKB:Q61337-1, Ser-136, MOD:00046." [PMID:12049737, PRO:JAN]

Yes

organism-modification

PR:000026137

Bcl2-associated agonist of cell death isoform 1 phosphorylated 6 (mouse)

mBAD/iso:1/Phos:6

"A Bcl2-associated agonist of cell death isoform 1 phosphorylated 6 in mouse. UniProtKB:Q61337-1, Ser-128/Ser-136, MOD:00046." [PMID:12049737, PRO:JAN]

Yes

organism-modification

PR:000026138

Bcl2-associated agonist of cell death isoform 1 phosphorylated 7 (mouse)

mBAD/iso:1/Phos:7

"A Bcl2-associated agonist of cell death isoform 1 phosphorylated 7 in mouse. UniProtKB:Q61337-1, Ser-112/Ser-155, MOD:00046." [PMID:10880354, PRO:CNA]

organism-modification

PR:000026139

Bcl2-associated agonist of cell death isoform 1 phosphorylated 8 (mouse)

mBAD/iso:1/Phos:8

"A Bcl2-associated agonist of cell death isoform 1 phosphorylated 8 in mouse. UniProtKB:Q61337-1, Ser-155, MOD:00046." [PMID:10880354, PRO:CNA]

Yes

organism-modification

PR:000026167

Bcl2-associated agonist of cell death isoform 1 phosphorylated 1 (mouse)

mBAD/iso:1/Phos:1

"A Bcl2-associated agonist of cell death isoform 1 phosphorylated 1 in mouse. UniProtKB:Q61337-1, Ser-112/Ser-136, MOD:00046." [PMID:10949026, PMID:8929531, PMID:9346240, PRO:JAN]

Yes

organism-modification

PR:000037809

Bcl2-associated agonist of cell death isoform 1 unphosphorylated 1 (mouse)

mBAD/iso:1/UnPhos:1

"A Bcl2-associated agonist of cell death isoform 1 (mouse) that lacks phosphorylation on the indicated Ser residues located within each of two RxRxxSxP motifs, and the indicated Ser residue within the motif RRxS in the BH3 domain, which is the major PKA phosphorylation site. Example: UniProtKB:Q61337-1, Ser-112/Ser-136/Ser-155, PR:000026291." [PMID:16403219, PRO:DAN, PRO:KER]

organism-modification

PR:000044747

Bcl2-associated agonist of cell death isoform 1 unmodified form (mouse)

mBAD/iso:1/UnMod

"A Bcl2-associated agonist of cell death isoform 1 unmodified form in mouse." [PRO:DNx]

Yes

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Functional Annotation (PRO-centric view)

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PRO Term	GO Annotation		Evidence
PR:000026133 mBAD/iso:1/Phos:2 UniProtKB:Q61337-1, Ser-112/Ser-136/Ser-155, MOD:00046	acts_upstream_of_or_within	GO:0043066 negative regulation of apoptotic process	PMID:10949026
	enables	NOT GO:0005515 protein binding with PR:000003237 fam:14-3-3	PMID:10949026
		NOT GO:0005515 protein binding with PR:P63101-1	PMID:10949026
		NOT GO:0005515 protein binding with PR:Q64373-1	PMID:10949026
		NOT GO:0005515 protein binding with PR:Q07817-1	PMID:10949026
PR:000026135 mBAD/iso:1/Phos:4 UniProtKB:Q61337-1, Thr-201, MOD:00047	acts_upstream_of_or_within	GO:0043066 negative regulation of apoptotic process	PMID:14967141
	enables	decreased GO:0005515 protein binding with PR:Q64373-1	PMID:14967141
PR:000026136 mBAD/iso:1/Phos:5 UniProtKB:Q61337-1, Ser-136, MOD:00046	enables	GO:0005515 protein binding with PR:P63101 KCIP-1 (mouse)	PMID:12049737
PR:000026137 mBAD/iso:1/Phos:6 UniProtKB:Q61337-1, Ser-128/Ser-136, MOD:00046	acts_upstream_of_or_within	GO:0051402 neuron apoptotic process	PMID:12049737
PR:000026139 mBAD/iso:1/Phos:8 UniProtKB:Q61337-1, Ser-155, MOD:00046	enables	GO:0071889 14-3-3 protein binding with PR:P61982 mYWHAG	PMID:10880354
PR:000026167 mBAD/iso:1/Phos:1 UniProtKB:Q61337-1, Ser-112/Ser-136, MOD:00046	enables	decreased GO:0005515 protein binding with PR:P62258-1	PMID:12049737
		decreased GO:0005515 protein binding with PR:Q07817-1	PMID:12049737
		decreased GO:0005515 protein binding with PR:Q9CQV8 KCIP-1 (mouse)	PMID:12049737
		decreased GO:0005515 protein binding with PR:P63101 KCIP-1 (mouse)	PMID:12049737
PR:000044747 mBAD/iso:1/UnMod	acts_upstream_of_or_within	GO:0006915 apoptotic process	PMID:15280015
	enables	GO:0005515 protein binding with PR:P04049 cRaf (human)	PMID:17011751
		GO:0005515 protein binding with PR:P06803-2	PMID:17011751
		GO:0005515 protein binding with PR:P15056 BRAF	PMID:17011751
		GO:0005515 protein binding with PR:Q04759 hPRKCQ	PMID:17011751
	located_in	GO:0031966 mitochondrial membrane	PMID:15280015