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Protein Ontology report - interferon regulatory factor 3 isoform 1 (human)
PR:Q14653-1 - http://purl.obolibrary.org/obo/PR_Q14653-1
 
  Protein Forms  Complex  Annotations      
Ontology Information Show OBO stanza / GPI
  PRO ID
PR:Q14653-1   
  PRO nameinterferon regulatory factor 3 isoform 1 (human) 
  Synonyms
PRO-Short-label: EXACT:hIRF3/iso:1
  Definition"An interferon regulatory factor 3 isoform 1 that is encoded in the genome of human." [PRO:CNA] 
  PRO Categoryorganism-sequence 
  ParentPR:000003257 interferon regulatory factor 3 isoform 1
PR:Q14653 interferon regulatory factor 3 (human)
  TaxonNCBITaxon:9606 Homo sapiens
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Sequence0                                                  Organism-Sequence 1                                        
         Modification0                                                  Organism-Modification 2                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:Q14653-1
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

Comp. In Complex?
organism-sequence


PR:Q14653-1
interferon regulatory factor 3 isoform 1 (human)
hIRF3/iso:1
"An interferon regulatory factor 3 isoform 1 that is encoded in the genome of human." [PRO:CNA]

organism-modification


PR:000025763
interferon regulatory factor 3 isoform 1 phosphorylated 1 (human)
hIRF3/iso:1/Phos:1
"An interferon regulatory factor 3 isoform 1 phosphorylated 1 in human. UniProtKB:Q14653-1, Ser-385/Ser-386, MOD:00046." [PMID:10805757, PRO:CNA]
Yes
Yes
organism-modification


PR:000045489
interferon regulatory factor 3 isoform 1 phosphorylated 2 (human)
hIRF3/iso:1/Phos:2
"An interferon regulatory factor 3 isoform 1 (human) that has been phosphorylated on the residue at the position equivalent to Ser-339 and on Ser and Thr residues within the 5ST site (Ser-396, Ser-398, Ser-402, Thr-404, and Ser-405). UniProtKB:Q14653-1, Ser-339/Ser-396/Ser-398/Ser-402/Ser-405, MOD:00046|Thr-404, MOD:00047." [PRO:CNA, Reactome:R-HSA-936418]

Yes
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hIRF3/iso:1 forms found in complexes   

hIRF3/iso:1 Component
 Complexes
PR:000025763 hIRF3/iso:1/Phos:1 PR:000036002 IRF3-P:IRF3-P:KPNA4 complex (human)
PR:000045489 hIRF3/iso:1/Phos:2 PR:000027084 IRF3-P:IRF7-P complex (human)
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000025763 hIRF3/iso:1/Phos:1
UniProtKB:Q14653-1, Ser-385/Ser-386, MOD:00046		 enablesGO:0005515 protein binding with PR:O14980 chromosome region maintenance 1 protein homolog (human) PMID:10805757
located_inGO:0005829 cytosol Reactome:REACT_7149