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Protein Ontology report - DNA topoisomerase 2-beta (human)
PR:Q02880 - http://purl.obolibrary.org/obo/PR_Q02880
 
  Protein Forms      
Ontology Information Show OBO stanza / GPI
  PRO ID
PR:Q02880   
  PRO nameDNA topoisomerase 2-beta (human) 
  Synonyms
PRO-Short-label: EXACT:hTOP2B
Gene-based: RELATED:TOP2B
Other: EXACT:DNA topoisomerase II, beta isozyme (human)
  Definition"A DNA topoisomerase 2-beta that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q02880
  PRO Categoryorganism-gene 
  ParentPR:000016545 DNA topoisomerase 2-beta
PR:000029067 Homo sapiens protein
  Gene TemplateHGNC:11990 TOP2B (human)
  TaxonNCBITaxon:9606 Homo sapiens
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene0                                                  Organism-Gene 1                                        
         Sequence0                                                  Organism-Sequence 2                                        
         Modification0                                                  Organism-Modification 7                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:Q02880
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
organism-gene



PR:Q02880

DNA topoisomerase 2-beta (human)

hTOP2B


"A DNA topoisomerase 2-beta that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q02880]


organism-sequence



PR:Q02880-1

DNA topoisomerase 2-beta isoform hBeta-2 (human)

hTOP2B/iso:hBeta-2


"A DNA topoisomerase 2-beta (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q02880-1." [PRO:DNx, UniProtKB:Q02880]


organism-sequence



PR:Q02880-2

DNA topoisomerase 2-beta isoform hBeta-1 (human)

hTOP2B/iso:hBeta-1


"A DNA topoisomerase 2-beta (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q02880-2." [PRO:DNx, UniProtKB:Q02880]


organism-modification



PR:000049510

DNA topoisomerase 2-beta sumoylated form (human)

hTOP2B/SumoLys+


"A DNA topoisomerase 2-beta (human) that includes at least one sumoylated lysine. UniProtKB:Q02880, MOD:01149." [PRO:DNx, Reactome:R-HSA-4641297]


organism-modification



PR:000071705

DNA topoisomerase 2-beta deaminated 1 (human)

hTOP2B/Deam:1


"A DNA topoisomerase 2-beta (human) that has been deaminated on the residue at the position equivalent to Asn-854 of the amino acid sequence represented by UniProtKB:Q02880-1. Example: UniProtKB:Q02880-1, Asn-854, MOD:00684." [IEDB_epitope:1353270, PRO:DNx]


organism-modification



PR:000074320

DNA topoisomerase 2-beta deaminated 2 (human)

hTOP2B/Deam:2


"A DNA topoisomerase 2-beta (human) that has been deaminated on the residue at the position equivalent to Asn-530 of the amino acid sequence represented by UniProtKB:Q02880-1. Example: UniProtKB:Q02880-1, Asn-530, MOD:00684." [IEDB_epitope:770065, PRO:DNx]


organism-modification



PR:000075112

DNA topoisomerase 2-beta citrullinated 1 (human)

hTOP2B/Cit:1


"A DNA topoisomerase 2-beta (human) that has been citrullinated on the residue at the position equivalent to Arg-836 of the amino acid sequence represented by UniProtKB:Q02880-1. Example: UniProtKB:Q02880-1, Arg-836, MOD:00219." [IEDB_epitope:1793929, PRO:DNx]


organism-modification



PR:000075259

DNA topoisomerase 2-beta deaminated 3 (human)

hTOP2B/Deam:3


"A DNA topoisomerase 2-beta (human) that has been deaminated on the residue at the position equivalent to Asn-529 of the amino acid sequence represented by UniProtKB:Q02880-1. Example: UniProtKB:Q02880-1, Asn-529, MOD:00684." [IEDB_epitope:770064, PRO:DNx]


organism-modification



PR:000076559

DNA topoisomerase 2-beta methylated 1 (human)

hTOP2B/Me:1


"A DNA topoisomerase 2-beta (human) that has been methylated on the residue at the position equivalent to Cys-754 of the amino acid sequence represented by UniProtKB:Q02880-1. Example: UniProtKB:Q02880-1, Cys-754, MOD:00660." [IEDB_epitope:1027691, PRO:DNx]


organism-modification



PR:000084991

DNA topoisomerase 2-beta deaminated 4 (human)

hTOP2B/Deam:4


"A DNA topoisomerase 2-beta (human) that has been deaminated on the residue at the position equivalent to Asn-845 of the amino acid sequence represented by UniProtKB:Q02880-1. Example: UniProtKB:Q02880-1, Asn-845, MOD:00684." [IEDB_epitope:838069, PRO:DNx]