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Protein Ontology report - vascular endothelial growth factor A, long form (mouse)
PR:Q00731 - http://purl.obolibrary.org/obo/PR_Q00731
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza / PAF / GPI
  PRO ID
PR:Q00731   
  PRO namevascular endothelial growth factor A, long form (mouse) 
  Synonyms
PRO-Short-label: EXACT:mVEGFA
Gene-based: RELATED:Vegf | Vegfa
Other: EXACT:L-VEGF (mouse) | vascular permeability factor (mouse) | VPF (mouse)
  Definition"A vascular endothelial growth factor A, long form that is encoded in the genome of mouse." [OMA:Q00731, PRO:DNx] 
  PRO Categoryorganism-gene 
  ParentPR:000017284 vascular endothelial growth factor A, long form
PR:000029032 Mus musculus protein
  Gene TemplateMGI:103178 Vegfa (mouse)
  TaxonNCBITaxon:10090 Mus musculus
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene0                                                  Organism-Gene 1                                        
         Sequence0                                                  Organism-Sequence 7                                        
         Modification0                                                  Organism-Modification 0                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:Q00731
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

Comp. In Complex?
organism-gene


PR:Q00731
vascular endothelial growth factor A, long form (mouse)
mVEGFA
"A vascular endothelial growth factor A, long form that is encoded in the genome of mouse." [OMA:Q00731, PRO:DNx]

organism-sequence


PR:Q00731-1
vascular endothelial growth factor A, long form isoform 1 (mouse)
mVEGFA/iso:1
"A vascular endothelial growth factor A, long form isoform 1 that is encoded in the genome of mouse." [PRO:CNA]

organism-sequence


PR:Q00731-2
vascular endothelial growth factor A, long form isoform 2 (mouse)
mVEGFA/iso:2
"A vascular endothelial growth factor A, long form isoform 2 that is encoded in the genome of mouse." [PMID:8614412, PRO:KRC]
Yes
organism-sequence


PR:Q00731-3
vascular endothelial growth factor A, long form isoform 3 (mouse)
mVEGFA/iso:3
"A vascular endothelial growth factor A, long form isoform 3 that is encoded in the genome of mouse." [PMID:8614412, PRO:KRC]
Yes
organism-sequence


PR:Q00731-4
vascular endothelial growth factor A, long form isoform 4 (mouse)
mVEGFA/iso:4
"A vascular endothelial growth factor A, long form (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q00731-4." [PMID:9446618, PRO:KRC]
Yes
organism-sequence


PR:Q00731-5
vascular endothelial growth factor A, long form isoform mVEGF-5 (mouse)
mVEGFA/iso:mVEGF-5
"A vascular endothelial growth factor A, long form (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q00731-5." [PRO:DNx, UniProtKB:Q00731]

organism-sequence


PR:Q00731-6
vascular endothelial growth factor A, long form isoform 6 (mouse)
mVEGFA/iso:6
"A vascular endothelial growth factor A, long form (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q00731-6." [PMID:11731620, PRO:KRC]

organism-sequence


PR:Q00731-7
vascular endothelial growth factor A, long form isoform mL-VEGF-2 (mouse)
mVEGFA/iso:mL-VEGF-2
"A vascular endothelial growth factor A, long form (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q00731-7." [PRO:DNx, UniProtKB:Q00731]

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Functional Annotation (GO-centric view) Switch to PRO Centric View     

Biological Process GO Term
Protein Forms & Complexes
Evidence
GO:0001525 angiogenesisPR:Q00731-2 mVEGFA/iso:2 MGI_ref:3758404; PMID:17626017
PR:Q00731-3 mVEGFA/iso:3 MGI_ref:3758404; PMID:17626017
GO:0001569 branching involved in blood vessel morphogenesisPR:Q00731-2 mVEGFA/iso:2 MGI_ref:3710026; PMID:17428830
GO:0001938 positive regulation of endothelial cell proliferationPR:Q00731-2 mVEGFA/iso:2 MGI_ref:74931; PMID:1592003
PR:Q00731-3 mVEGFA/iso:3 MGI_ref:74931; PMID:1592003
PR:Q00731-4 mVEGFA/iso:4 MGI_ref:1195544; PMID:9446618
GO:0002053 positive regulation of mesenchymal cell proliferationPR:Q00731-2 mVEGFA/iso:2 MGI_ref:3613102; PMID:16375885
GO:0030324 lung developmentPR:Q00731-2 mVEGFA/iso:2 MGI_ref:3613102; PMID:16375885
GO:0048010 vascular endothelial growth factor receptor signaling pathwayPR:Q00731-2 mVEGFA/iso:2 MGI_ref:74931; PMID:1592003
PR:Q00731-3 mVEGFA/iso:3 MGI_ref:74931; PMID:1592003
GO:0048754 branching morphogenesis of an epithelial tubePR:Q00731-2 mVEGFA/iso:2 MGI_ref:3613102; PMID:16375885
GO:0060426 lung vasculature developmentPR:Q00731-2 mVEGFA/iso:2 MGI_ref:1927039; PMID:11066091

Molecular Function GO Term
Protein Forms & Complexes
Evidence
GO:0005102 signaling receptor bindingPR:Q00731-2 mVEGFA/iso:2 MGI_ref:3758404; PMID:17626017
GO:0005515 protein bindingPR:Q00731-2 mVEGFA/iso:2 MGI_ref:1860784; PMID:10705382
GO:0008083 growth factor activityPR:Q00731-4 mVEGFA/iso:4 MGI_ref:1195544; PMID:9446618
GO:0008201 heparin bindingPR:Q00731-2 mVEGFA/iso:2 MGI_ref:77585; PMID:8614412
PR:Q00731-2 mVEGFA/iso:2 MGI_ref:77585; PMID:8614412
PR:Q00731-2 mVEGFA/iso:2 MGI_ref:77585; PMID:8614412
PR:Q00731-2 mVEGFA/iso:2 MGI_ref:77585; PMID:8614412
PR:Q00731-2 mVEGFA/iso:2 MGI_ref:77585; PMID:8614412
PR:Q00731-2 mVEGFA/iso:2 MGI_ref:77585; PMID:8614412
PR:Q00731-2 mVEGFA/iso:2 MGI_ref:77585; PMID:8614412
PR:Q00731-2 mVEGFA/iso:2 MGI_ref:77585; PMID:8614412
PR:Q00731-2 mVEGFA/iso:2 MGI_ref:77585; PMID:8614412
PR:Q00731-2 mVEGFA/iso:2 MGI_ref:77585; PMID:8614412
PR:Q00731-2 mVEGFA/iso:2 MGI_ref:77585; PMID:8614412
PR:Q00731-2 mVEGFA/iso:2 MGI_ref:77585; PMID:8614412
GO:0043183 vascular endothelial growth factor receptor 1 bindingPR:Q00731-2 mVEGFA/iso:2 MGI_ref:3758404; PMID:17626017
GO:0043184 vascular endothelial growth factor receptor 2 bindingPR:Q00731-2 mVEGFA/iso:2 MGI_ref:1860784; PMID:10705382
PR:Q00731-2 mVEGFA/iso:2 MGI_ref:1860784; PMID:10705382
PR:Q00731-2 mVEGFA/iso:2 MGI_ref:1860784; PMID:10705382
PR:Q00731-2 mVEGFA/iso:2 MGI_ref:1860784; PMID:10705382
PR:Q00731-2 mVEGFA/iso:2 MGI_ref:1860784; PMID:10705382
PR:Q00731-2 mVEGFA/iso:2 MGI_ref:1860784; PMID:10705382
PR:Q00731-2 mVEGFA/iso:2 MGI_ref:1860784; PMID:10705382
PR:Q00731-2 mVEGFA/iso:2 MGI_ref:1860784; PMID:10705382
PR:Q00731-2 mVEGFA/iso:2 MGI_ref:1860784; PMID:10705382
PR:Q00731-2 mVEGFA/iso:2 MGI_ref:1860784; PMID:10705382
PR:Q00731-2 mVEGFA/iso:2 MGI_ref:1860784; PMID:10705382
PR:Q00731-2 mVEGFA/iso:2 MGI_ref:1860784; PMID:10705382
GO:0050840 extracellular matrix bindingPR:Q00731-2 mVEGFA/iso:2 MGI_ref:3758404; PMID:17626017

Cellular Location GO Term
Protein Forms & Complexes
Evidence
GO:0005576 extracellular regionPR:Q00731-2 mVEGFA/iso:2 MGI_ref:77585; PMID:8614412
PR:Q00731-3 mVEGFA/iso:3 MGI_ref:77585; PMID:8614412
PR:Q00731-4 mVEGFA/iso:4 MGI_ref:1195544; PMID:9446618
GO:0005615 extracellular spacePR:Q00731-3 mVEGFA/iso:3 MGI_ref:74931; PMID:1592003