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Protein Ontology report - pituitary homeobox 2 (mouse)
PR:P97474 - http://purl.obolibrary.org/obo/PR_P97474
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza / PAF / GPI
  PRO ID
PR:P97474   
  PRO namepituitary homeobox 2 (mouse) 
  Synonyms
PRO-Short-label: EXACT:mPITX2
Gene-based: RELATED:Arp1 | Brx1 | Otlx2 | Pitx2 | Ptx2 | Rgs | Rieg
Other: EXACT:ALL1-responsive protein ARP1 (mouse) | bicoid-related homeobox protein 1 (mouse) | BRX1 homeoprotein (mouse) | homeobox protein PITX2 (mouse) | orthodenticle-like homeobox 2 (mouse) | paired-like homeodomain transcription factor 2 (mouse) | solurshin (mouse)
  Definition"A pituitary homeobox 2 that is encoded in the genome of mouse." [OMA:P97474, PRO:DNx] 
  PRO Categoryorganism-gene 
  ParentPR:000000117 pituitary homeobox 2
PR:000029032 Mus musculus protein
  Gene TemplateMGI:109340 Pitx2 (mouse)
  TaxonNCBITaxon:10090 Mus musculus
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene0                                                  Organism-Gene 1                                        
         Sequence0                                                  Organism-Sequence 6                                        
         Modification0                                                  Organism-Modification 0                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:P97474
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

Comp. In Complex?
organism-gene


PR:P97474 pituitary homeobox 2 (mouse)
mPITX2

organism-sequence


PR:000036295 pituitary homeobox 2 isoform 4 (mouse)
mPITX2/iso:4

organism-sequence


PR:P97474-1 pituitary homeobox 2 isoform Ptx2B (mouse)
mPITX2/iso:Ptx2B
Yes
organism-sequence


PR:P97474-2 pituitary homeobox 2 isoform Ptx2C (mouse)
mPITX2/iso:Ptx2C
Yes
organism-sequence


PR:P97474-3 pituitary homeobox 2 isoform Ptx2A (mouse)
mPITX2/iso:Ptx2A
Yes
organism-sequence


PR:P97474-4 pituitary homeobox 2 isoform Ptx2Calpha (mouse)
mPITX2/iso:Ptx2Calpha

organism-sequence


PR:P97474-5 pituitary homeobox 2 isoform Ptx2Cbeta (mouse)
mPITX2/iso:Ptx2Cbeta

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Functional Annotation (GO-centric view) Switch to PRO Centric View     

Biological Process GO Term
Protein Forms & Complexes
Evidence
GO:0007179 transforming growth factor beta receptor signaling pathwayPR:P97474-2 mPITX2/iso:Ptx2C PMID:10585561
GO:0007266 Rho protein signal transductionPR:P97474-3 mPITX2/iso:Ptx2A PMID:11854422
GO:0007368 determination of left/right symmetryPR:P97474-1 mPITX2/iso:Ptx2B PMID:12397115
PR:P97474-2 mPITX2/iso:Ptx2C PMID:9708732
NOT GO:0007368 determination of left/right symmetryPR:P97474-3 mPITX2/iso:Ptx2A PMID:10585561
GO:0007520 myoblast fusionPR:P97474-2 mPITX2/iso:Ptx2C MGI_ref:3686567; PMID:16958127
GO:0009887 animal organ morphogenesisPR:P97474-2 mPITX2/iso:Ptx2C PMID:10585561
GO:0016055 Wnt signaling pathwayPR:P97474-1 mPITX2/iso:Ptx2B PMID:12464179
GO:0030036 actin cytoskeleton organizationPR:P97474-3 mPITX2/iso:Ptx2A PMID:11854422
GO:0043388 positive regulation of DNA bindingPR:P97474-3 mPITX2/iso:Ptx2A MGI_ref:3796777; PMID:18458156
GO:2000288 positive regulation of myoblast proliferationPR:P97474-2 mPITX2/iso:Ptx2C MGI_ref:3686567; PMID:16958127

Molecular Function GO Term
Protein Forms & Complexes
Evidence
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specificPR:P97474-3 mPITX2/iso:Ptx2A MGI_ref:3796777; PMID:18458156
GO:0003677 DNA bindingPR:P97474-3 mPITX2/iso:Ptx2A MGI_ref:3796777; PMID:18458156
GO:0003712 transcription coregulator activityPR:P97474-3 mPITX2/iso:Ptx2A MGI_ref:3796777; PMID:18458156
GO:0005515 protein bindingPR:P97474-3 mPITX2/iso:Ptx2A MGI_ref:3796777; PMID:18458156
GO:0008134 transcription factor bindingPR:P97474-3 mPITX2/iso:Ptx2A PMID:15385555

Cellular Location GO Term
Protein Forms & Complexes
Evidence
GO:0005634 nucleusPR:P97474-3 mPITX2/iso:Ptx2A PMID:11854422
PR:P97474-3 mPITX2/iso:Ptx2A PMID:11854422
PR:P97474-3 mPITX2/iso:Ptx2A PMID:11854422
PR:P97474-3 mPITX2/iso:Ptx2A PMID:11854422
PR:P97474-3 mPITX2/iso:Ptx2A PMID:11854422
PR:P97474-3 mPITX2/iso:Ptx2A PMID:11854422
PR:P97474-3 mPITX2/iso:Ptx2A PMID:11854422
PR:P97474-3 mPITX2/iso:Ptx2A PMID:11854422
PR:P97474-3 mPITX2/iso:Ptx2A PMID:11854422
PR:P97474-3 mPITX2/iso:Ptx2A PMID:11854422
GO:0005667 transcription factor complexPR:P97474-1 mPITX2/iso:Ptx2B PMID:12464179; PMID:15385555