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Protein Ontology report - mothers against decapentaplegic homolog 3 isoform 1 (human)
PR:P84022-1 - http://purl.obolibrary.org/obo/PR_P84022-1
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza / PAF / GPI
  PRO ID
PR:P84022-1   
  PRO namemothers against decapentaplegic homolog 3 isoform 1 (human) 
  Synonyms
PRO-Short-label: EXACT:hSMAD3/iso:1
  Definition"A smad3 isoform 1 that is encoded in the genome of human." [PRO:CNA] 
  CommentRequested by=PubChem. 
  PRO Categoryorganism-sequence 
  ParentPR:000000475 smad3 isoform 1
PR:P84022 mothers against decapentaplegic homolog 3 (human)
  TaxonNCBITaxon:9606 Homo sapiens
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Sequence0                                                  Organism-Sequence 1                                        
         Modification0                                                  Organism-Modification 2                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:P84022-1
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

Comp. In Complex?
organism-sequence


PR:P84022-1 mothers against decapentaplegic homolog 3 isoform 1 (human)
hSMAD3/iso:1
Yes
organism-modification


PR:000026333 smad3 isoform 1 phosphorylated 1 (human)
hSMAD3/iso:1/Phos:1
Yes
organism-modification


PR:000036557 smad3 isoform 1 acetylated and phosphorylated 1 (human)
hSMAD3/iso:1/AcPhos:1
Yes
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Functional Annotation (GO-centric view) Switch to PRO Centric View     

Biological Process GO Term
Protein Forms & Complexes
Evidence
GO:0006366 transcription by RNA polymerase IIPR:000026333 hSMAD3/iso:1/Phos:1 PMID:10823886
GO:0007179 transforming growth factor beta receptor signaling pathwayPR:000026333 hSMAD3/iso:1/Phos:1 PMID:8774881; PMID:9380693
PR:000036557 hSMAD3/iso:1/AcPhos:1 PMID:17074756
PR:P84022-1 hSMAD3/iso:1 PMID:8774881

Molecular Function GO Term
Protein Forms & Complexes
Evidence
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specificPR:000026333 hSMAD3/iso:1/Phos:1 PMID:10823886; PMID:12943993
GO:0003700 DNA-binding transcription factor activityPR:000036557 hSMAD3/iso:1/AcPhos:1 PMID:17074756
GO:0005515 protein bindingPR:P84022-1 hSMAD3/iso:1 PMID:12154125
PR:P84022-1 hSMAD3/iso:1 PMID:12154125
PR:P84022-1 hSMAD3/iso:1 PMID:12154125
PR:P84022-1 hSMAD3/iso:1 PMID:12154125
PR:P84022-1 hSMAD3/iso:1 PMID:12154125
PR:P84022-1 hSMAD3/iso:1 PMID:12154125
GO:0008134 transcription factor bindingPR:000026333 hSMAD3/iso:1/Phos:1 PMID:15084259
GO:0046332 SMAD bindingPR:000026333 hSMAD3/iso:1/Phos:1 PMID:15350224; PMID:9311995

Cellular Location GO Term
Protein Forms & Complexes
Evidence
GO:0005634 nucleusPR:000026333 hSMAD3/iso:1/Phos:1 PMID:10846168; PMID:15280432
PR:000036557 hSMAD3/iso:1/AcPhos:1 PMID:17074756
GO:0005667 transcription factor complexPR:000026333 hSMAD3/iso:1/Phos:1 PMID:12374795
GO:0005737 cytoplasmPR:P84022-1 hSMAD3/iso:1 PMID:17074053