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Protein Ontology report - disintegrin and metalloproteinase domain-containing protein 17 (human)
PR:P78536 - http://purl.obolibrary.org/obo/PR_P78536
 
  Protein Forms      
Ontology Information Show OBO stanza / GPI
  PRO ID
PR:P78536   
  PRO namedisintegrin and metalloproteinase domain-containing protein 17 (human) 
  Synonyms
PRO-Short-label: EXACT:hADAM17
Gene-based: RELATED:ADAM17 | CSVP | TACE
Other: EXACT:ADAM 17 (human) | CD156b (human) | snake venom-like protease (human) | TNF-alpha convertase (human) | TNF-alpha-converting enzyme (human)
  Definition"An ADAM 17 endopeptidase that is encoded in the genome of human." [PRO:WCB, UniProtKB:P78536] 
  PRO Categoryorganism-gene 
  ParentPR:000001279 ADAM 17 endopeptidase
PR:000029067 Homo sapiens protein
  Gene TemplateHGNC:195 ADAM17 (human)
  TaxonNCBITaxon:9606 Homo sapiens
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene0                                                  Organism-Gene 1                                        
         Sequence0                                                  Organism-Sequence 2                                        
         Modification0                                                  Organism-Modification 7                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:P78536
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

Comp. In Complex?
organism-gene


PR:P78536
disintegrin and metalloproteinase domain-containing protein 17 (human)
hADAM17
"An ADAM 17 endopeptidase that is encoded in the genome of human." [PRO:WCB, UniProtKB:P78536]

organism-sequence


PR:P78536-1
disintegrin and metalloproteinase domain-containing protein 17 isoform A (human)
hADAM17/iso:A
"A disintegrin and metalloproteinase domain-containing protein 17 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P78536-1." [PRO:DNx, UniProtKB:P78536]

organism-sequence


PR:P78536-2
disintegrin and metalloproteinase domain-containing protein 17 isoform B (human)
hADAM17/iso:B
"A disintegrin and metalloproteinase domain-containing protein 17 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P78536-2." [PRO:DNx, UniProtKB:P78536]

organism-modification


PR:000045859
disintegrin and metalloproteinase domain-containing protein 17 phosphorylated 1 (human)
hADAM17/Phos:1
"A disintegrin and metalloproteinase domain-containing protein 17 (human) that has been phosphorylated on the residue at the position equivalent to Thr-735 of the amino acid sequence represented by UniProtKB:P78536-1. Example: UniProtKB:P78536-1, Thr-735, MOD:00047." [iPTMnet:P78536, PMID:12058067, PMID:18722532]

organism-modification


PR:000056691
disintegrin and metalloproteinase domain-containing protein 17 N-glycosylated 1 (human)
hADAM17/NGlyco:1
"A disintegrin and metalloproteinase domain-containing protein 17 (human) that has been N-glycosylated at the residue equivalent to Asn-264 of the amino acid sequence represented by UniProtKB:P78536-1, in which the glycan composition is represented by GlyTouCan:G37399XV. Example: UniProtKB:P78536-1, Asn-264, MOD:00160~GNO:G37399XV." [GlyGen:P78536-1, PMID:29741879, PRO:DNx]

organism-modification


PR:000056692
disintegrin and metalloproteinase domain-containing protein 17 N-glycosylated 2 (human)
hADAM17/NGlyco:2
"A disintegrin and metalloproteinase domain-containing protein 17 (human) that has been N-glycosylated at the residue equivalent to Asn-264 of the amino acid sequence represented by UniProtKB:P78536-1, in which the glycan composition is represented by GlyTouCan:G83633GK. Example: UniProtKB:P78536-1, Asn-264, MOD:00160~GNO:G83633GK." [GlyGen:P78536-1, PMID:29741879, PRO:DNx]

organism-modification


PR:000074459
disintegrin and metalloproteinase domain-containing protein 17 methylated 1 (human)
hADAM17/Me:1
"A disintegrin and metalloproteinase domain-containing protein 17 (human) that has been methylated on the residue at the position equivalent to Cys-469 of the amino acid sequence represented by UniProtKB:P78536-1. Example: UniProtKB:P78536-1, Cys-469, MOD:00660." [IEDB_epitope:1009153, PRO:DNx]

organism-modification


PR:000076090
disintegrin and metalloproteinase domain-containing protein 17 deaminated 1 (human)
hADAM17/Deam:1
"A disintegrin and metalloproteinase domain-containing protein 17 (human) that has been deaminated on the residue at the position equivalent to Asn-103 of the amino acid sequence represented by UniProtKB:P78536-1. Example: UniProtKB:P78536-1, Asn-103, MOD:00684." [IEDB_epitope:1343685, PRO:DNx]

organism-modification


PR:000078552
disintegrin and metalloproteinase domain-containing protein 17, mature form (human)
hADAM17/mature
"A disintegrin and metalloproteinase domain-containing protein 17 (human) that has had the signal peptide and propeptide removed. Example: UniProtKB:P78536-1, 215-824." [PRO:DNx, Reactome:R-HSA-179878, Reactome:R-HSA-9662839, Reactome:R-HSA-9663048]

organism-modification


PR:000081164
disintegrin and metalloproteinase domain-containing protein 17 methylated 2 (human)
hADAM17/Me:2
"A disintegrin and metalloproteinase domain-containing protein 17 (human) that has been methylated on the residue at the position equivalent to Cys-333 of the amino acid sequence represented by UniProtKB:P78536-1. Example: UniProtKB:P78536-1, Cys-333, MOD:00660." [IEDB_epitope:1019927, PRO:DNx]