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Protein Ontology report - thiopurine S-methyltransferase (human)
PR:P51580 - http://purl.obolibrary.org/obo/PR_P51580
 
  Protein Forms      
Ontology Information Show OBO stanza / GPI
  PRO ID
PR:P51580   
  PRO namethiopurine S-methyltransferase (human) 
  Synonyms
PRO-Short-label: EXACT:hTPMT
Gene-based: RELATED:TPMT
Other: EXACT:thiopurine methyltransferase (human)
  Definition"A thiopurine S-methyltransferase that is encoded in the genome of human." [PRO:DNx, UniProtKB:P51580
  PRO Categoryorganism-gene 
  ParentPR:000016583 thiopurine S-methyltransferase
PR:000029067 Homo sapiens protein
  Gene TemplateHGNC:12014 TPMT (human)
  TaxonNCBITaxon:9606 Homo sapiens
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene0                                                  Organism-Gene 1                                        
         Sequence0                                                  Organism-Sequence 4                                        
         Modification0                                                  Organism-Modification 2                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:P51580
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
organism-gene



PR:P51580

thiopurine S-methyltransferase (human)

hTPMT


"A thiopurine S-methyltransferase that is encoded in the genome of human." [PRO:DNx, UniProtKB:P51580]


organism-sequence



PR:000061398

thiopurine S-methyltransferase sequence variant A167G (human)

hTPMT/var:A167G


"A thiopurine S-methyltransferase (human) that has a Gly residue at the position equivalent to Ala-167 of the amino acid sequence represented by UniProtKB:P51580. UniProtKB:P51580, Ala-167, CHEBI:29947." [PRO:DNx, Reactome:R-HSA-5603357]


organism-sequence



PR:000061449

thiopurine S-methyltransferase sequence variant A154T (human)

hTPMT/var:A154T


"A thiopurine S-methyltransferase (human) that has a Thr residue at the position equivalent to Ala-154 of the amino acid sequence represented by UniProtKB:P51580. UniProtKB:P51580, Ala-154, CHEBI:30013." [PRO:DNx, Reactome:R-HSA-5603333]


organism-sequence



PR:000062262

thiopurine S-methyltransferase sequence variant Y240C (human)

hTPMT/var:Y240C


"A thiopurine S-methyltransferase (human) that has a Cys residue at the position equivalent to Tyr-240 of the amino acid sequence represented by UniProtKB:P51580. UniProtKB:P51580, Tyr-240, CHEBI:29950." [PRO:DNx, Reactome:R-HSA-5603343]


organism-sequence



PR:000064030

thiopurine S-methyltransferase sequence variant A80P (human)

hTPMT/var:A80P


"A thiopurine S-methyltransferase (human) that has a Pro residue at the position equivalent to Ala-80 of the amino acid sequence represented by UniProtKB:P51580. UniProtKB:P51580, Ala-80, CHEBI:50342." [PRO:DNx, Reactome:R-HSA-5603346]


organism-modification



PR:000072859

thiopurine S-methyltransferase cysteinylated 1 (human)

hTPMT/Cyst:1


"A thiopurine S-methyltransferase (human) that has been cysteinylated on the residue at the position equivalent to Cys-70 of the amino acid sequence represented by UniProtKB:P51580. UniProtKB:P51580, Cys-70, MOD:00765." [IEDB_epitope:636524, PRO:DNx]


organism-modification



PR:000074148

thiopurine S-methyltransferase methylated 1 (human)

hTPMT/Me:1


"A thiopurine S-methyltransferase (human) that has been methylated on the residue at the position equivalent to Cys-70 of the amino acid sequence represented by UniProtKB:P51580. UniProtKB:P51580, Cys-70, MOD:00660." [IEDB_epitope:1046556, PRO:DNx]