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Protein Ontology report - tuberin (human)
PR:P49815 - http://purl.obolibrary.org/obo/PR_P49815
 
  Protein Forms      
Ontology Information Show OBO stanza / GPI
  PRO ID
PR:P49815   
  PRO nametuberin (human) 
  Synonyms
PRO-Short-label: EXACT:hTSC2
Gene-based: RELATED:TSC2 | TSC4
Other: EXACT:tuberous sclerosis 2 protein (human)
  Definition"A tuberin that is encoded in the genome of human." [PRO:DNx, UniProtKB:P49815] 
  PRO Categoryorganism-gene 
  ParentPR:000016709 tuberin
PR:000029067 Homo sapiens protein
  Gene TemplateHGNC:12363 TSC2 (human)
  TaxonNCBITaxon:9606 Homo sapiens
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene0                                                  Organism-Gene 1                                        
         Sequence0                                                  Organism-Sequence 8                                        
         Modification0                                                  Organism-Modification 11                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:P49815
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

Comp. In Complex?
organism-gene


PR:P49815
tuberin (human)
hTSC2
"A tuberin that is encoded in the genome of human." [PRO:DNx, UniProtKB:P49815]

organism-sequence


PR:P49815-1
tuberin isoform 1 (human)
hTSC2/iso:1
"A tuberin isoform 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P49815]

organism-sequence


PR:P49815-2
tuberin isoform h2 (human)
hTSC2/iso:h2
"A tuberin (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P49815-2." [PRO:DNx, UniProtKB:P49815]

organism-sequence


PR:P49815-3
tuberin isoform h3 (human)
hTSC2/iso:h3
"A tuberin (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P49815-3." [PRO:DNx, UniProtKB:P49815]

organism-sequence


PR:P49815-4
tuberin isoform h4 (human)
hTSC2/iso:h4
"A tuberin (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P49815-4." [PRO:DNx, UniProtKB:P49815]

organism-sequence


PR:P49815-5
tuberin isoform h5 (human)
hTSC2/iso:h5
"A tuberin (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P49815-5." [PRO:DNx, UniProtKB:P49815]

organism-sequence


PR:P49815-6
tuberin isoform h6 (human)
hTSC2/iso:h6
"A tuberin (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P49815-6." [PRO:DNx, UniProtKB:P49815]

organism-sequence


PR:P49815-7
tuberin isoform h7 (human)
hTSC2/iso:h7
"A tuberin (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P49815-7." [PRO:DNx, UniProtKB:P49815]

organism-sequence


PR:P49815-8
tuberin isoform h8 (human)
hTSC2/iso:h8
"A tuberin (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P49815-8." [PRO:DNx, UniProtKB:P49815]

organism-modification


PR:000045806
tuberin phosphorylated 1 (human)
hTSC2/Phos:1
"A tuberin (human) that has been phosphorylated on the residue at the position equivalent to Tyr-1571 of the amino acid sequence represented by UniProtKB:P49815-1. Example: UniProtKB:P49815-1, Tyr-1571, MOD:00048." [iPTMnet:P49815, PMID:11290735]

organism-modification


PR:000049554
tuberin phosphorylated 2 (human)
hTSC2/Phos:2
"A tuberin (human) that has been phosphorylated on the residue at the position equivalent to Ser-1387 of the amino acid sequence represented by UniProtKB:P49815. UniProtKB:P49815, Ser-1387, MOD:00046." [PRO:DNx, Reactome:R-HSA-3132769]

organism-modification


PR:000049555
tuberin phosphorylated 3 (human)
hTSC2/Phos:3
"A tuberin (human) that has been phosphorylated on the residue at the position equivalent to Ser-939, and phosphothreonine at position 1462 of the amino acid sequence represented by UniProtKB:P49815. UniProtKB:P49815, Ser-939, MOD:00046|Thr-1462, MOD:00047." [PRO:DNx, Reactome:R-HSA-199484]

organism-modification


PR:000049556
tuberin phosphorylated 4 (human)
hTSC2/Phos:4
"A tuberin (human) that has been post-translationally modified to include phosphoserine at positions 939 and 1130, and phosphothreonine at position 1462 of the amino acid sequence represented by UniProtKB:P49815. UniProtKB:P49815, Ser-939/Ser-1130, MOD:00046|Thr-1462, MOD:00047." [PRO:DNx, Reactome:R-HSA-165164]

organism-modification


PR:000069359
tuberin phosphorylated 5 (human)
hTSC2/Phos:5
"A tuberin (human) that has been phosphorylated on the residue at the position equivalent to Thr-1059 of the amino acid sequence represented by UniProtKB:P49815-1. Example: UniProtKB:P49815-1, Thr-1059, MOD:00047." [IEDB_epitope:2148836, PRO:DNx]

organism-modification


PR:000073763
tuberin cysteinylated 1 (human)
hTSC2/Cyst:1
"A tuberin (human) that has been cysteinylated on the residue at the position equivalent to Cys-65 of the amino acid sequence represented by UniProtKB:P49815-1. Example: UniProtKB:P49815-1, Cys-65, MOD:00765." [IEDB_epitope:776947, PRO:DNx]

organism-modification


PR:000079487
tuberin methylated 1 (human)
hTSC2/Me:1
"A tuberin (human) that has been methylated on the residue at the position equivalent to Cys-1755 of the amino acid sequence represented by UniProtKB:P49815-1. Example: UniProtKB:P49815-1, Cys-1755, MOD:00660." [IEDB_epitope:1045055, PRO:DNx]

organism-modification


PR:000081087
tuberin cysteinylated 2 (human)
hTSC2/Cyst:2
"A tuberin (human) that has been cysteinylated on the residue at the position equivalent to Cys-227 of the amino acid sequence represented by UniProtKB:P49815-1. Example: UniProtKB:P49815-1, Cys-227, MOD:00765." [IEDB_epitope:1585125, PRO:DNx]

organism-modification


PR:000082494
tuberin methylated 2 (human)
hTSC2/Me:2
"A tuberin (human) that has been methylated on the residue at the position equivalent to Cys-65 of the amino acid sequence represented by UniProtKB:P49815-1. Example: UniProtKB:P49815-1, Cys-65, MOD:00660." [IEDB_epitope:1043823, PRO:DNx]

organism-modification


PR:000082517
tuberin deaminated 1 (human)
hTSC2/Deam:1
"A tuberin (human) that has been deaminated on the residue at the position equivalent to Gln-572 of the amino acid sequence represented by UniProtKB:P49815-1. Example: UniProtKB:P49815-1, Gln-572, MOD:00685." [IEDB_epitope:1341913, PRO:DNx]

organism-modification


PR:000083425
tuberin deaminated 2 (human)
hTSC2/Deam:2
"A tuberin (human) that has been deaminated on the residue at the position equivalent to Gln-220 of the amino acid sequence represented by UniProtKB:P49815-1. Example: UniProtKB:P49815-1, Gln-220, MOD:00685." [IEDB_epitope:1976063, PRO:DNx]