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Protein Ontology report - interleukin-6 receptor subunit beta (human)
PR:P40189 - http://purl.obolibrary.org/obo/PR_P40189
 
  Protein Forms      
Ontology Information Show OBO stanza / GPI
  PRO ID
PR:P40189   
  PRO nameinterleukin-6 receptor subunit beta (human) 
  Synonyms
PRO-Short-label: EXACT:hIL6ST
Gene-based: RELATED:IL6ST
Other: EXACT:CD130 (human) | CDw130 (human) | gp130 (human) | IL-6 receptor subunit beta (human) | IL-6R subunit beta (human) | IL-6R-beta (human) | IL-6RB (human) | interleukin-6 signal transducer (human) | membrane glycoprotein 130 (human) | oncostatin-M receptor subunit alpha (human)
  Definition"An interleukin-6 receptor subunit beta that is encoded in the genome of human." [PRO:WCB, UniProtKB:P40189
  PRO Categoryorganism-gene 
  ParentPR:000001868 interleukin-6 receptor subunit beta
PR:000029067 Homo sapiens protein
  Gene TemplateHGNC:6021 IL6ST (human)
  TaxonNCBITaxon:9606 Homo sapiens
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene0                                                  Organism-Gene 1                                        
         Sequence0                                                  Organism-Sequence 3                                        
         Modification0                                                  Organism-Modification 12                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:P40189
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
organism-gene



PR:P40189

interleukin-6 receptor subunit beta (human)

hIL6ST


"An interleukin-6 receptor subunit beta that is encoded in the genome of human." [PRO:WCB, UniProtKB:P40189]


organism-sequence



PR:P40189-1

interleukin-6 receptor subunit beta isoform h1 (human)

hIL6ST/iso:h1


"An interleukin-6 receptor subunit beta (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P40189-1." [PRO:DNx, UniProtKB:P40189]


organism-modification



PR:000060572

interleukin-6 receptor subunit beta isoform h1, signal peptide removed phosphorylated 1 (human)

hIL6ST/iso:h1/SigPep-/Phos:1


"An interleukin-6 receptor subunit beta isoform h1 (human) that has had the signal peptide removed and that has been phosphorylated on the residues at the positions equivalent to Tyr-759, Tyr-767, Tyr-814, Tyr-905, and Tyr-915 of the amino acid sequence represented by UniProtKB:P40189-1. UniProtKB:P40189-1, 23-918, Tyr-759/Tyr-767/Tyr-814/Tyr-905/Tyr-915, MOD:00048." [PRO:DNx, Reactome:R-HSA-1112580]


organism-sequence



PR:P40189-2

interleukin-6 receptor subunit beta isoform h2 (human)

hIL6ST/iso:h2


"An interleukin-6 receptor subunit beta (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P40189-2." [PRO:DNx, UniProtKB:P40189]


organism-modification



PR:000063018

interleukin-6 receptor subunit beta isoform h2, signal peptide removed form (human)

hIL6ST/iso:h2/SigPep-


"An interleukin-6 receptor subunit beta isoform h2 (human) that has had the signal peptide removed. UniProtKB:P40189-2, 23-329." [PRO:DNx, Reactome:R-HSA-1067653]


organism-sequence



PR:P40189-3

interleukin-6 receptor subunit beta isoform h3 (human)

hIL6ST/iso:h3


"An interleukin-6 receptor subunit beta (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P40189-3." [PRO:DNx, UniProtKB:P40189]


organism-modification



PR:000048030

interleukin-6 receptor subunit beta, signal peptide removed form (human)

hIL6ST/SigPep-


"An interleukin-6 receptor subunit beta (human) that has had the signal peptide removed. UniProtKB:P40189, 23-918." [PRO:DNx, Reactome:R-HSA-448453]


organism-modification



PR:000062547

interleukin-6 receptor subunit beta, signal peptide removed phosphotyrosine form (human)

hIL6ST/SigPep-/PhosTyr+


"An interleukin-6 receptor subunit beta (human) that has had the signal peptide removed and that includes at least one phosphorylated tyrosine. Example: UniProtKB:P40189-1, 23-918, MOD:00048." [PRO:DNx, Reactome:R-HSA-8950439]


organism-modification



PR:000060572

interleukin-6 receptor subunit beta isoform h1, signal peptide removed phosphorylated 1 (human)

hIL6ST/iso:h1/SigPep-/Phos:1


"An interleukin-6 receptor subunit beta isoform h1 (human) that has had the signal peptide removed and that has been phosphorylated on the residues at the positions equivalent to Tyr-759, Tyr-767, Tyr-814, Tyr-905, and Tyr-915 of the amino acid sequence represented by UniProtKB:P40189-1. UniProtKB:P40189-1, 23-918, Tyr-759/Tyr-767/Tyr-814/Tyr-905/Tyr-915, MOD:00048." [PRO:DNx, Reactome:R-HSA-1112580]


organism-modification



PR:000063018

interleukin-6 receptor subunit beta isoform h2, signal peptide removed form (human)

hIL6ST/iso:h2/SigPep-


"An interleukin-6 receptor subunit beta isoform h2 (human) that has had the signal peptide removed. UniProtKB:P40189-2, 23-329." [PRO:DNx, Reactome:R-HSA-1067653]


organism-modification



PR:000056496

interleukin-6 receptor subunit beta N-glycosylated 1 (human)

hIL6ST/NGlyco:1


"An interleukin-6 receptor subunit beta (human) that has been N-glycosylated at the residue equivalent to Asn-379 of the amino acid sequence represented by UniProtKB:P40189-1, in which the glycan composition is represented by GlyTouCan:G58001LT. Example: UniProtKB:P40189-1, Asn-379, MOD:00160~GNO:G58001LT." [GlyGen:P40189-1, PMID:23345538, PRO:DNx]


organism-modification



PR:000056497

interleukin-6 receptor subunit beta N-glycosylated 2 (human)

hIL6ST/NGlyco:2


"An interleukin-6 receptor subunit beta (human) that has been N-glycosylated at the residue equivalent to Asn-390 of the amino acid sequence represented by UniProtKB:P40189-1, in which the glycan composition is represented by GlyTouCan:G72787SB. Example: UniProtKB:P40189-1, Asn-390, MOD:00160~GNO:G72787SB." [GlyGen:P40189-1, PMID:23345538, PRO:DNx]


organism-modification



PR:000056499

interleukin-6 receptor subunit beta N-glycosylated 4 (human)

hIL6ST/NGlyco:4


"An interleukin-6 receptor subunit beta (human) that has been N-glycosylated at the residue equivalent to Asn-818 of the amino acid sequence represented by UniProtKB:P40189-1, in which the glycan composition is represented by GlyTouCan:G58001LT. Example: UniProtKB:P40189-1, Asn-818, MOD:00160~GNO:G58001LT." [GlyGen:P40189-1, PMID:23345538, PRO:DNx]


organism-modification



PR:000062547

interleukin-6 receptor subunit beta, signal peptide removed phosphotyrosine form (human)

hIL6ST/SigPep-/PhosTyr+


"An interleukin-6 receptor subunit beta (human) that has had the signal peptide removed and that includes at least one phosphorylated tyrosine. Example: UniProtKB:P40189-1, 23-918, MOD:00048." [PRO:DNx, Reactome:R-HSA-8950439]


organism-modification



PR:000060572

interleukin-6 receptor subunit beta isoform h1, signal peptide removed phosphorylated 1 (human)

hIL6ST/iso:h1/SigPep-/Phos:1


"An interleukin-6 receptor subunit beta isoform h1 (human) that has had the signal peptide removed and that has been phosphorylated on the residues at the positions equivalent to Tyr-759, Tyr-767, Tyr-814, Tyr-905, and Tyr-915 of the amino acid sequence represented by UniProtKB:P40189-1. UniProtKB:P40189-1, 23-918, Tyr-759/Tyr-767/Tyr-814/Tyr-905/Tyr-915, MOD:00048." [PRO:DNx, Reactome:R-HSA-1112580]


organism-modification



PR:000068058

interleukin-6 receptor subunit beta cysteinylated 1 (human)

hIL6ST/Cyst:1


"An interleukin-6 receptor subunit beta (human) that has been cysteinylated on the residue at the position equivalent to Cys-172 of the amino acid sequence represented by UniProtKB:P40189-1. Example: UniProtKB:P40189-1, Cys-172, MOD:00765." [IEDB_epitope:2130349, IEDB_epitope:2130350, PRO:DNx]


organism-modification



PR:000072161

interleukin-6 receptor subunit beta deaminated 1 (human)

hIL6ST/Deam:1


"An interleukin-6 receptor subunit beta (human) that has been deaminated on the residue at the position equivalent to Asn-63 of the amino acid sequence represented by UniProtKB:P40189-1. Example: UniProtKB:P40189-1, Asn-63, MOD:00684." [IEDB_epitope:1736716, PRO:DNx]


organism-modification



PR:000074605

interleukin-6 receptor subunit beta deaminated 2 (human)

hIL6ST/Deam:2


"An interleukin-6 receptor subunit beta (human) that has been deaminated on the residue at the position equivalent to Asn-383 of the amino acid sequence represented by UniProtKB:P40189-1. Example: UniProtKB:P40189-1, Asn-383, MOD:00684." [IEDB_epitope:1997686, PRO:DNx]


organism-modification



PR:000076538

interleukin-6 receptor subunit beta phosphorylated 1 (human)

hIL6ST/Phos:1


"An interleukin-6 receptor subunit beta (human) that has been phosphorylated on the residue at the position equivalent to Ser-839 of the amino acid sequence represented by UniProtKB:P40189-1. Example: UniProtKB:P40189-1, Ser-839, MOD:00046." [IEDB_epitope:1587962, PRO:DNx]


organism-modification



PR:000081988

interleukin-6 receptor subunit beta phosphorylated 2 (human)

hIL6ST/Phos:2


"An interleukin-6 receptor subunit beta (human) that has been phosphorylated on the residue at the position equivalent to Ser-838 of the amino acid sequence represented by UniProtKB:P40189-1. Example: UniProtKB:P40189-1, Ser-838, MOD:00046." [IEDB_epitope:1587961, PRO:DNx]