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Protein Ontology report - beta-adrenergic receptor kinase 1 (human)
PR:P25098 - http://purl.obolibrary.org/obo/PR_P25098
 
  Protein Forms  Complex      
Ontology Information Show OBO stanza / GPI
  PRO ID
PR:P25098   
  PRO namebeta-adrenergic receptor kinase 1 (human) 
  Synonyms
PRO-Short-label: EXACT:hGRK2
Gene-based: RELATED:ADRBK1 | BARK | BARK1 | GRK2
Other: EXACT:beta-ARK-1 (human) | G-protein coupled receptor kinase 2 (human)
  Definition"A beta-adrenergic receptor kinase 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P25098
  PRO Categoryorganism-gene 
  ParentPR:000003791 beta-adrenergic receptor kinase 1
PR:000029067 Homo sapiens protein
  Gene TemplateHGNC:289 GRK2 (human)
  TaxonNCBITaxon:9606 Homo sapiens
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene0                                                  Organism-Gene 1                                        
         Sequence0                                                  Organism-Sequence 1                                        
         Modification0                                                  Organism-Modification 6                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:P25098
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
organism-gene



PR:P25098

beta-adrenergic receptor kinase 1 (human)

hGRK2


"A beta-adrenergic receptor kinase 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P25098]


Yes
organism-sequence



PR:P25098-1

beta-adrenergic receptor kinase 1 isoform 1 (human)

hGRK2/iso:1


"A beta-adrenergic receptor kinase 1 isoform 1 that is encoded in the genome of human." [PRO:DNx]


organism-modification



PR:000045725

beta-adrenergic receptor kinase 1 phosphorylated 1 (human)

hGRK2/Phos:1


"A beta-adrenergic receptor kinase 1 (human) that has been phosphorylated at Ser-685. UniProtKB:P25098, Ser-685, MOD:00046." [iPTMnet:P25098, PMID:11278469]


organism-modification



PR:000046279

beta-adrenergic receptor kinase 1 phosphorylated 2 (human)

hGRK2/Phos:2


"A beta-adrenergic receptor kinase 1 (human) that has been phosphorylated on the residue at the position equivalent to Ser-29 of the amino acid sequence represented by UniProtKB:P25098. UniProtKB:P25098, Ser-29, MOD:00046." [PRO:DNx, Reactome:R-HSA-111969]


organism-modification



PR:000079819

beta-adrenergic receptor kinase 1 methylated 1 (human)

hGRK2/Me:1


"A beta-adrenergic receptor kinase 1 (human) that has been methylated on the residue at the position equivalent to Cys-439 of the amino acid sequence represented by UniProtKB:P25098. UniProtKB:P25098, Cys-439, MOD:00660." [IEDB_epitope:1006596, PRO:DNx]


organism-modification



PR:000080621

beta-adrenergic receptor kinase 1 phosphorylated 3 (human)

hGRK2/Phos:3


"A beta-adrenergic receptor kinase 1 (human) that has been phosphorylated on the residue at the position equivalent to Tyr-466 of the amino acid sequence represented by UniProtKB:P25098. UniProtKB:P25098, Tyr-466, MOD:00048." [IEDB_epitope:1367116, PRO:DNx]


organism-modification



PR:000082342

beta-adrenergic receptor kinase 1 phosphorylated 4 (human)

hGRK2/Phos:4


"A beta-adrenergic receptor kinase 1 (human) that has been phosphorylated on the residue at the position equivalent to Ser-501 of the amino acid sequence represented by UniProtKB:P25098. UniProtKB:P25098, Ser-501, MOD:00046." [IEDB_epitope:1320649, PRO:DNx]


organism-modification



PR:000085211

beta-adrenergic receptor kinase 1 phosphorylated 5 (human)

hGRK2/Phos:5


"A beta-adrenergic receptor kinase 1 (human) that has been phosphorylated on the residue at the position equivalent to Ser-670 of the amino acid sequence represented by UniProtKB:P25098. UniProtKB:P25098, Ser-670, MOD:00046." [IEDB_epitope:238668, PRO:DNx]


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hGRK2 forms found in complexes   

hGRK2 Component
Complexes
PR:P25098 hGRK2 PR:000028441 GRK2:calmodulin (human)