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Protein Ontology report - nuclear factor NF-kappa-B p105 subunit (human)
PR:P19838 - http://purl.obolibrary.org/obo/PR_P19838
 
  Protein Forms  Complex  Annotations      
Ontology Information Show OBO stanza / GPI
  PRO ID
PR:P19838   
  PRO namenuclear factor NF-kappa-B p105 subunit (human) 
  Synonyms
PRO-Short-label: EXACT:hNFKB1
Gene-based: RELATED:NFKB1
Other: EXACT:DNA-binding factor KBF1 (human) | EBP-1 (human) | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (human)
  Definition"A nuclear factor NF-kappa-B p105 subunit that is encoded in the genome of human." [PRO:DNx] 
  PRO Categoryorganism-gene 
  ParentPR:000001754 nuclear factor NF-kappa-B p105 subunit
PR:000029067 Homo sapiens protein
  Gene TemplateHGNC:7794 NFKB1 (human)
  TaxonNCBITaxon:9606 Homo sapiens
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene0                                                  Organism-Gene 1                                        
         Sequence0                                                  Organism-Sequence 3                                        
         Modification0                                                  Organism-Modification 8                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:P19838
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
organism-gene



PR:P19838

nuclear factor NF-kappa-B p105 subunit (human)

hNFKB1


"A nuclear factor NF-kappa-B p105 subunit that is encoded in the genome of human." [PRO:DNx]


Yes
organism-sequence



PR:P19838-1

nuclear factor NF-kappa-B p105 subunit isoform 1 (human)

hNFKB1/iso:1


"A nuclear factor NF-kappa-B p105 subunit isoform 2 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P19838]


organism-sequence



PR:P19838-2

nuclear factor NF-kappa-B p105 subunit isoform 2 (human)

hNFKB1/iso:2


"A nuclear factor NF-kappa-B p105 subunit isoform 3 that is encoded in the genome of human." [PRO:JAN]


organism-sequence



PR:P19838-3

nuclear factor NF-kappa-B p105 subunit isoform h3 (human)

hNFKB1/iso:h3


"A nuclear factor NF-kappa-B p105 subunit (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P19838-3." [PRO:DNx, UniProtKB:P19838]


organism-modification



PR:000035834

nuclear factor NF-kappa-B p50 subunit (human)

hNFKBp50


"A nuclear factor NF-kappa-B p50 subunit in human. Example: UniProtKB:P19838-1, 1-433." [PRO:DNx, UniProtKB:P19838]

Yes

Yes
organism-modification



PR:000045706

nuclear factor NF-kappa-B p105 subunit phosphorylated 1 (human)

hNFKB1/Phos:1


"A nuclear factor NF-kappa-B p105 subunit (human) that has been phosphorylated on the residue at the position equivalent to Ser-927 of the amino acid sequence represented by UniProtKB:P19838-1. Example: UniProtKB:P19838-1, Ser-927, MOD:00046." [iPTMnet:P19838, PMID:11297557, PMID:11976329]


organism-modification



PR:000048595

nuclear factor NF-kappa-B p105 subunit phosphorylated 2 (human)

hNFKB1/Phos:2


"A nuclear factor NF-kappa-B p105 subunit (human) that has been post-translationally modified to include phosphoserine at positions 927 and 932 of the amino acid sequence represented by UniProtKB:P19838. UniProtKB:P19838, Ser-927/Ser-932, MOD:00046." [PRO:DNx, Reactome:R-HSA-451611]


organism-modification



PR:000064699

nuclear factor NF-kappa-B p105 subunit phosphorylated and ubiquitinated 1 (human)

hNFKB1/PhosUbiq:1


"A nuclear factor NF-kappa-B p105 subunit (human) that has been phosphorylated on the residues at the positions equivalent to Ser-927 and Ser-932 of the amino acid sequence represented by UniProtKB:P19838-1 and that includes at least three ubiquitinated lysines. Example: UniProtKB:P19838-1, Ser-927/Ser-932, MOD:00046|MOD:01148(3+)." [PRO:DNx, Reactome:R-HSA-451619]


organism-modification



PR:000072853

nuclear factor NF-kappa-B p105 subunit deaminated 1 (human)

hNFKB1/Deam:1


"A nuclear factor NF-kappa-B p105 subunit (human) that has been deaminated on the residue at the position equivalent to Gln-45 of the amino acid sequence represented by UniProtKB:P19838-1. Example: UniProtKB:P19838-1, Gln-45, MOD:00685." [IEDB_epitope:929719, PRO:DNx]


organism-modification



PR:000075491

nuclear factor NF-kappa-B p105 subunit cysteinylated 1 (human)

hNFKB1/Cyst:1


"A nuclear factor NF-kappa-B p105 subunit (human) that has been cysteinylated on the residue at the position equivalent to Cys-666 of the amino acid sequence represented by UniProtKB:P19838-1. Example: UniProtKB:P19838-1, Cys-666, MOD:00765." [IEDB_epitope:1050024, PRO:DNx]


organism-modification



PR:000080523

nuclear factor NF-kappa-B p105 subunit deaminated 2 (human)

hNFKB1/Deam:2


"A nuclear factor NF-kappa-B p105 subunit (human) that has been deaminated on the residue at the position equivalent to Asn-456 of the amino acid sequence represented by UniProtKB:P19838-1. Example: UniProtKB:P19838-1, Asn-456, MOD:00684." [IEDB_epitope:1350766, PRO:DNx]


organism-modification



PR:000083954

nuclear factor NF-kappa-B p105 subunit deaminated 3 (human)

hNFKB1/Deam:3


"A nuclear factor NF-kappa-B p105 subunit (human) that has been deaminated on the residue at the position equivalent to Gln-878 of the amino acid sequence represented by UniProtKB:P19838-1. Example: UniProtKB:P19838-1, Gln-878, MOD:00685." [IEDB_epitope:1844356, PRO:DNx]


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hNFKB1 forms found in complexes   

hNFKB1 Component
Complexes
PR:000035834 hNFKBp50 PR:000035835 NF-kappaB p50/p65 complex (human)
PR:P19838 hNFKB1 PR:000028444 NFKB p105:TPL2:ABIN2 (human)
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Functional Annotation (GO-centric view) Switch to PRO Centric View     

Biological Process GO Term

Protein Forms & Complexes

Evidence
GO:0034142 toll-like receptor 4 signaling pathwayPR:000035834 hNFKBp50 Reactome:REACT_6894