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Protein Ontology report - interferon-induced, double-stranded RNA-activated protein kinase (human)
PR:P19525 -
http://purl.obolibrary.org/obo/PR_P19525
Protein Forms
Ontology Information
Show OBO stanza
/
GPI
PRO ID
PR:P19525
PRO name
interferon-induced, double-stranded RNA-activated protein kinase (human)
Synonyms
PRO-Short-label
:
EXACT:
hEIF2AK2
Gene-based
:
RELATED:
EIF2AK2 | PKR | PRKR
Other
:
EXACT:
eIF-2A protein kinase 2 (human) | eukaryotic translation initiation factor 2-alpha kinase 2 (human) | interferon-inducible RNA-dependent protein kinase (human) | P1/eIF-2A protein kinase (human) | p68 kinase (human) | protein kinase R (human) | protein kinase RNA-activated (human) | tyrosine-protein kinase EIF2AK2 (human)
Definition
"An interferon-induced, double-stranded RNA-activated protein kinase that is encoded in the genome of human." [PRO:DNx,
UniProtKB:P19525
]
PRO Category
organism-gene
Parent
PR:000006959
interferon-induced, double-stranded RNA-activated protein kinase
PR:000029067
Homo sapiens protein
Gene Template
HGNC:9437
EIF2AK2 (human)
Taxon
NCBITaxon:9606
Homo sapiens
Terms by PRO Category
Organism-Independent
Organism-Specific
Category
Number of Terms
Category
Number of Terms
Gene
0
Organism-Gene
1
Sequence
0
Organism-Sequence
2
Modification
0
Organism-Modification
4
Term Hierarchy
Visualization
DAG:
OLS:
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Related Cross References
Db identifiers
UniProtKB:P19525
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Protein Forms
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Compact View
Category
PRO ID
Name
Short Name
Definition
Ann.
Has Annotation?
Comp.
In Complex?
organism-gene
PR:P19525
interferon-induced, double-stranded RNA-activated protein kinase (human)
hEIF2AK2
"An interferon-induced, double-stranded RNA-activated protein kinase that is encoded in the genome of human." [PRO:DNx, UniProtKB:P19525]
organism-sequence
PR:P19525-1
interferon-induced, double-stranded RNA-activated protein kinase isoform 1 (human)
hEIF2AK2/iso:1
"An interferon-induced, double-stranded RNA-activated protein kinase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P19525-1." [PRO:DNx, UniProtKB:P19525]
organism-sequence
PR:P19525-2
interferon-induced, double-stranded RNA-activated protein kinase isoform h2 (human)
hEIF2AK2/iso:h2
"An interferon-induced, double-stranded RNA-activated protein kinase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P19525-2." [PRO:DNx, UniProtKB:P19525]
organism-modification
PR:000045703
interferon-induced, double-stranded RNA-activated protein kinase phosphorylated 1 (human)
hEIF2AK2/Phos:1
"An interferon-induced, double-stranded RNA-activated protein kinase (human) that has been phosphorylated on the residue at the position equivalent to Thr-451 of the amino acid sequence represented by UniProtKB:P19525-1. Example: UniProtKB:P19525-1, Thr-451, MOD:00047." [iPTMnet:P19525, PMID:17404396]
organism-modification
PR:000047263
interferon-induced, double-stranded RNA-activated protein kinase, initiator methionine removed form (human)
hEIF2AK2/InitMet-
"An interferon-induced, double-stranded RNA-activated protein kinase (human) that has had the initiator methionine removed. UniProtKB:P19525, 2-551." [PRO:DNx, Reactome:R-HSA-168699]
organism-modification
PR:000064543
interferon-induced, double-stranded RNA-activated protein kinase, initiator methionine removed phosphorylated 1 (human)
hEIF2AK2/InitMet-/Phos:1
"An interferon-induced, double-stranded RNA-activated protein kinase (human) that has had the initiator methionine removed and that has been phosphorylated on the residues at the positions equivalent to Thr-88, Thr-89, Thr-90, Tyr-101, Tyr-162, Ser-242, Thr-255, Thr-258, Tyr-293, Thr-446, and Thr-451 of the amino acid sequence represented by UniProtKB:P19525-1. Example: UniProtKB:P19525-1, 2-551, Thr-88/Thr-89/Thr-90/Thr-255/Thr-258/Thr-446/Thr-451, MOD:00047|Tyr-101/Tyr-162/Tyr-293, MOD:00048|Ser-242, MOD:00046." [PRO:DNx, Reactome:R-HSA-9833834, Reactome:R-HSA-9836332]
organism-modification
PR:000077363
interferon-induced, double-stranded RNA-activated protein kinase cysteinylated 1 (human)
hEIF2AK2/Cyst:1
"An interferon-induced, double-stranded RNA-activated protein kinase (human) that has been cysteinylated on the residue at the position equivalent to Cys-485 of the amino acid sequence represented by UniProtKB:P19525-1. Example: UniProtKB:P19525-1, Cys-485, MOD:00765." [IEDB_epitope:926944, PRO:DNx]
