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Protein Ontology report - bone morphogenetic protein 7 (human)
PR:P18075 - http://purl.obolibrary.org/obo/PR_P18075
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza / PAF / GPI
  PRO ID
PR:P18075   
  PRO namebone morphogenetic protein 7 (human) 
  Synonyms
PRO-Short-label: EXACT:hBMP7
Gene-based: RELATED:BMP7 | OP1
Other: EXACT:BMP-7 (human) | eptotermin alfa (human) | OP-1 (human) | osteogenic protein 1 (human)
  Definition"A bone morphogenetic protein 7 that is encoded in the genome of human." [PRO:CNA, UniProtKB:P18075] 
  PRO Categoryorganism-gene 
  ParentPR:000000168 bone morphogenetic protein 7
PR:000029067 Homo sapiens protein
  Gene TemplateHGNC:1074 BMP7 (human)
  TaxonNCBITaxon:9606 Homo sapiens
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene0                                                  Organism-Gene 1                                        
         Sequence0                                                  Organism-Sequence 1                                        
         Modification0                                                  Organism-Modification 3                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:P18075
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

Comp. In Complex?
organism-gene


PR:P18075
bone morphogenetic protein 7 (human)
hBMP7
"A bone morphogenetic protein 7 that is encoded in the genome of human." [PRO:CNA, UniProtKB:P18075]

organism-sequence


PR:P18075-1
bone morphogenetic protein 7 isoform 1 (human)
hBMP7/iso:1
"A bone morphogenetic protein 7 isoform 1 that is encoded in the genome of human." [PRO:CNA]
Yes
organism-modification


PR:000036517
bone morphogenetic protein 7 isoform 1, mature N-glycosylated 1 (human)
hBMP7/iso:1/mature/NGlyco:1
"A bone morphogenetic protein 7 isoform 1, mature N-glycosylated 1 in human. UniProtKB:P18075-1, 293-431, Asn-372, MOD:00160." [PMID:15047707, PMID:15929982, PMID:8570652, PMID:9872992, PRO:CNA, PRO:DAN]
Yes
organism-modification


PR:000036519
bone morphogenetic protein 7 isoform 1, mature N-glycosylated 2 (human)
hBMP7/iso:1/mature/NGlyco:2
"A bone morphogenetic protein 7 isoform 1, mature N-glycosylated 2 in human, in which the cleaved parts remain joined by disulfide bonds. UniProtKB:P18075-1, 20-292, 293-431, Asn-372, MOD:00160." [PMID:15929982, PRO:CNA, PRO:DAN]
Yes
organism-modification


PR:000073618
bone morphogenetic protein 7, mature form (human)
hBMP7/mature
"A bone morphogenetic protein 7 (human) that has had the signal peptide and propeptide removed. UniProtKB:P18075, 293-431." [PRO:DNx, Reactome:R-HSA-206257]

organism-modification


PR:000036517
bone morphogenetic protein 7 isoform 1, mature N-glycosylated 1 (human)
hBMP7/iso:1/mature/NGlyco:1
"A bone morphogenetic protein 7 isoform 1, mature N-glycosylated 1 in human. UniProtKB:P18075-1, 293-431, Asn-372, MOD:00160." [PMID:15047707, PMID:15929982, PMID:8570652, PMID:9872992, PRO:CNA, PRO:DAN]
Yes
organism-modification


PR:000036519
bone morphogenetic protein 7 isoform 1, mature N-glycosylated 2 (human)
hBMP7/iso:1/mature/NGlyco:2
"A bone morphogenetic protein 7 isoform 1, mature N-glycosylated 2 in human, in which the cleaved parts remain joined by disulfide bonds. UniProtKB:P18075-1, 20-292, 293-431, Asn-372, MOD:00160." [PMID:15929982, PRO:CNA, PRO:DAN]
Yes
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Functional Annotation (GO-centric view) Switch to PRO Centric View     

Biological Process GO Term
Protein Forms & Complexes
Evidence
GO:0001501 skeletal system developmentPR:P18075-1 hBMP7/iso:1 PMID:2357959

Molecular Function GO Term
Protein Forms & Complexes
Evidence
GO:0005102 signaling receptor bindingPR:000036517 hBMP7/iso:1/mature/NGlyco:1 PMID:9872992
NOT GO:0005102 signaling receptor bindingPR:000036519 hBMP7/iso:1/mature/NGlyco:2 PMID:15929982
GO:0005515 protein bindingPR:P18075-1 hBMP7/iso:1 PMID:12805376
GO:0042803 protein homodimerization activityPR:000036517 hBMP7/iso:1/mature/NGlyco:1 PMID:15929982; PMID:8570652

Cellular Location GO Term
Protein Forms & Complexes
Evidence
GO:0005615 extracellular spacePR:000036517 hBMP7/iso:1/mature/NGlyco:1 PMID:15047707; PMID:15929982
PR:000036519 hBMP7/iso:1/mature/NGlyco:2 PMID:15929982
GO:0005794 Golgi apparatusPR:P18075-1 hBMP7/iso:1 PMID:12805376