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Protein Ontology report - transcription factor Sp1 (human)
PR:P08047 - http://purl.obolibrary.org/obo/PR_P08047
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza / PAF / GPI
  PRO ID
PR:P08047   
  PRO nametranscription factor Sp1 (human) 
  Synonyms
PRO-Short-label: EXACT:hSP1
Gene-based: RELATED:SP1 | TSFP1
  Definition"A transcription factor Sp1 that is encoded in the genome of human." [PRO:CNA, UniProtKB:P08047
  PRO Categoryorganism-gene 
  ParentPR:000000133 transcription factor Sp1
PR:000029067 Homo sapiens protein
  Gene TemplateHGNC:11205 SP1 (human)
  TaxonNCBITaxon:9606 Homo sapiens
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene0                                                  Organism-Gene 1                                        
         Sequence0                                                  Organism-Sequence 3                                        
         Modification0                                                  Organism-Modification 14                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:P08047
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
organism-gene



PR:P08047

transcription factor Sp1 (human)

hSP1


"A transcription factor Sp1 that is encoded in the genome of human." [PRO:CNA, UniProtKB:P08047]


organism-sequence



PR:P08047-1

transcription factor Sp1 isoform 1 (human)

hSP1/iso:1


"A transcription factor Sp1 isoform 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P08047]

Yes

organism-modification



PR:000028672

transcription factor Sp1 isoform 1 acetylated 2 (human)

hSP1/iso:1/Ac:2


"A transcription factor Sp1 isoform 1 acetylated 2 in human. UniProtKB:P08047-1, Lys-703, MOD:00064." [PMID:16478997, PRO:PD]


organism-modification



PR:000036496

transcription factor Sp1 isoform 1 acetylated 1 (human)

hSP1/iso:1/Ac:1


"A transcription factor Sp1 isoform 1 acetylated 1 in human." [PMID:15647279, PRO:CNA]

Yes

organism-modification



PR:000036497

transcription factor Sp1 isoform 1 cleaved 1 (human)

hSP1/iso:1/Clv:1


"A transcription factor Sp1 isoform 1 cleaved 1 in human. UniProtKB:P08047-1, 65-785." [PMID:16407261, PRO:CNA]

Yes

organism-modification



PR:000036498

transcription factor Sp1 isoform 1 O-glycosylated 1 (human)

hSP1/iso:1/OGlyco:1


"A transcription factor Sp1 isoform 1 O-glycosylated 1 in human. UniProtKB:P08047-1, Ser-491, MOD:00805." [PMID:11371615, PMID:9343410, PRO:CNA, PRO:DAN]

Yes

organism-modification



PR:000036499

transcription factor Sp1 isoform 1 phosphorylated 1 (human)

hSP1/iso:1/Phos:1


"A transcription factor Sp1 isoform 1 phosphorylated 1 in human." [PMID:2170018, PMID:9525578, PRO:CNA]

Yes

organism-modification



PR:000036500

transcription factor Sp1 isoform 1 phosphorylated 2 (human)

hSP1/iso:1/Phos:2


"A transcription factor Sp1 isoform 1 phosphorylated 2 in human. UniProtKB:P08047-1, Thr-579, MOD:00047." [PMID:9153193, PRO:CNA]

Yes

organism-modification



PR:000036501

transcription factor Sp1 isoform 1 phosphorylated 3 (human)

hSP1/iso:1/Phos:3


"A transcription factor Sp1 isoform 1 phosphorylated 3 in human. UniProtKB:P08047-1, Ser-59, MOD:00046." [PMID:17049555, PMID:18239466, PRO:CNA]

Yes

organism-modification



PR:000036502

transcription factor Sp1 isoform 1 phosphorylated 4 (human)

hSP1/iso:1/Phos:4


"A transcription factor Sp1 isoform 1 phosphorylated 4 in human." [PMID:18171990, PRO:CNA]

Yes

organism-modification



PR:000036503

transcription factor Sp1 isoform 1 sumoylated 1 (human)

hSP1/iso:1/Sumo:1


"A transcription factor Sp1 isoform 1 sumoylated 1 in human. UniProtKB:P08047-1, Lys-16, MOD:01149." [PMID:16407261, PRO:CNA]

Yes

organism-sequence



PR:P08047-2

transcription factor Sp1 isoform h2 (human)

hSP1/iso:h2


"A transcription factor Sp1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P08047-2." [PRO:DNx, UniProtKB:P08047]


organism-sequence



PR:P08047-3

transcription factor Sp1 isoform h3 (human)

hSP1/iso:h3


"A transcription factor Sp1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P08047-3." [PRO:DNx, UniProtKB:P08047]


organism-modification



PR:000045654

transcription factor Sp1 phosphorylated 1 (human)

hSP1/Phos:1


"A transcription factor Sp1 (human) that has been phosphorylated on the residue at the position equivalent to Thr-739 of the amino acid sequence represented by UniProtKB:P08047-1. Example: UniProtKB:P08047-1, Thr-739, MOD:00047." [iPTMnet:P08047, PMID:22266860]


organism-modification



PR:000049324

transcription factor Sp1, initiator methionine removed form (human)

hSP1/InitMet-


"A transcription factor Sp1 (human) that has had the initiator methionine removed. UniProtKB:P08047, 2-785." [PRO:DNx, Reactome:R-HSA-1592223]


organism-modification



PR:000069002

transcription factor Sp1 methylated 1 (human)

hSP1/Me:1


"A transcription factor Sp1 (human) that has been methylated on the residue at the position equivalent to Cys-755 of the amino acid sequence represented by UniProtKB:P08047-1. Example: UniProtKB:P08047-1, Cys-755, MOD:00660." [IEDB_epitope:1007012, PRO:DNx]


organism-modification



PR:000073305

transcription factor Sp1 deaminated 1 (human)

hSP1/Deam:1


"A transcription factor Sp1 (human) that has been deaminated on the residue at the position equivalent to Asn-244 of the amino acid sequence represented by UniProtKB:P08047-1. Example: UniProtKB:P08047-1, Asn-244, MOD:00684." [IEDB_epitope:1583104, PRO:DNx]


organism-modification



PR:000080651

transcription factor Sp1 cysteinylated 1 (human)

hSP1/Cyst:1


"A transcription factor Sp1 (human) that has been cysteinylated on the residue at the position equivalent to Cys-755 of the amino acid sequence represented by UniProtKB:P08047-1. Example: UniProtKB:P08047-1, Cys-755, MOD:00765." [IEDB_epitope:876858, PRO:DNx]


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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000036496 hSP1/iso:1/Ac:1 acts_upstream_of_or_withinGO:0007179 transforming growth factor beta receptor signaling pathway PMID:15647279
enablesGO:0003677 DNA binding PMID:15647279
located_inGO:0005634 nucleus PMID:15647279
PR:000036497 hSP1/iso:1/Clv:1
UniProtKB:P08047-1, 65-785
enablesGO:0003700 DNA-binding transcription factor activity PMID:16407261
located_inGO:0005634 nucleus PMID:16407261
PR:000036498 hSP1/iso:1/OGlyco:1
UniProtKB:P08047-1, Ser-491, MOD:00805
enablesGO:0003677 DNA binding PMID:11371615
increased GO:0003700 DNA-binding transcription factor activity relative to PR:000036497 hSP1/iso:1/Clv:1 PMID:11371615
located_inGO:0005634 nucleus PMID:11371615
PR:000036499 hSP1/iso:1/Phos:1 enablesGO:0003677 DNA binding PMID:2170018
located_inGO:0005634 nucleus PMID:2170018; PMID:9525578
PR:000036500 hSP1/iso:1/Phos:2
UniProtKB:P08047-1, Thr-579, MOD:00047
enablesdecreased GO:0003700 DNA-binding transcription factor activity relative to PR:000036497 hSP1/iso:1/Clv:1 PMID:9153193
located_inGO:0005634 nucleus PMID:9153193
PR:000036501 hSP1/iso:1/Phos:3
UniProtKB:P08047-1, Ser-59, MOD:00046
enablesincreased GO:0003700 DNA-binding transcription factor activity relative to PR:000036497 hSP1/iso:1/Clv:1 PMID:17049555; PMID:18239466
located_inGO:0005634 nucleus PMID:17049555; PMID:18239466
PR:000036502 hSP1/iso:1/Phos:4 acts_upstream_of_or_withinGO:0042770 signal transduction in response to DNA damage PMID:18171990
located_inGO:0005634 nucleus PMID:18171990
PR:000036503 hSP1/iso:1/Sumo:1
UniProtKB:P08047-1, Lys-16, MOD:01149
enablesdecreased GO:0003700 DNA-binding transcription factor activity relative to PR:000036497 hSP1/iso:1/Clv:1 PMID:16407261
PR:P08047-1 hSP1/iso:1 located_inGO:0005634 nucleus PMID:2170018