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Protein Ontology report - cyclin-dependent kinase 1 (human)
PR:P06493 - http://purl.obolibrary.org/obo/PR_P06493
 
  Protein Forms  Complex      
Ontology Information Show OBO stanza / GPI
  PRO ID
PR:P06493   
  PRO namecyclin-dependent kinase 1 (human) 
  Synonyms
PRO-Short-label: EXACT:hCDK1
Gene-based: RELATED:CDC2 | CDC28A | CDK1 | CDKN1 | P34CDC2
Other: EXACT:cell division control protein 2 homolog (human) | cell division protein kinase 1 (human) | p34 protein kinase (human)
  Definition"A cyclin-dependent kinase 1 that is encoded in the genome of human." [PRO:CNA, UniProtKB:P06493] 
  PRO Categoryorganism-gene 
  ParentPR:000003271 cyclin-dependent kinase 1
PR:000029067 Homo sapiens protein
  Gene TemplateHGNC:1722 CDK1 (human)
  TaxonNCBITaxon:9606 Homo sapiens
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene0                                                  Organism-Gene 1                                        
         Sequence0                                                  Organism-Sequence 2                                        
         Modification0                                                  Organism-Modification 12                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:P06493
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

Comp. In Complex?
organism-gene


PR:P06493
cyclin-dependent kinase 1 (human)
hCDK1
"A cyclin-dependent kinase 1 that is encoded in the genome of human." [PRO:CNA, UniProtKB:P06493]

organism-sequence


PR:P06493-1
cyclin-dependent kinase 1 isoform 1 (human)
hCDK1/iso:1
"A cyclin-dependent kinase 1 isoform 1 that is encoded in the genome of human." [PRO:CNx]

organism-modification


PR:000026181
cyclin-dependent kinase 1 isoform 1 phosphorylated 1 (human)
hCDK1/iso:1/Phos:1
"A cyclin-dependent kinase 1 isoform 1 phosphorylated 1 in human. UniProtKB:P06493-1, Thr-14, MOD:00047." [PRO:CNA]

Yes
organism-modification


PR:000026211
cyclin-dependent kinase 1 isoform 1 phosphorylated 2 (human)
hCDK1/iso:1/Phos:2
"A cyclin-dependent kinase 1 isoform 1 phosphorylated 2 in human. UniProtKB:P06493-1, Thr-161, MOD:00047." [PRO:CNx, Reactome:R-HSA-157415, Reactome:R-HSA-170066]

Yes
organism-modification


PR:000027123
cyclin-dependent kinase 1 isoform 1 phosphorylated 3 (human)
hCDK1/iso:1/Phos:3
"A cyclin-dependent kinase 1 isoform 1 phosphorylated 3 in human. UniProtKB:P06493-1, Thr-14/Thr-161, MOD:00047." [PRO:DAN, Reactome:R-HSA-170078]

Yes
organism-modification


PR:000027124
cyclin-dependent kinase 1 isoform 1 phosphorylated 4 (human)
hCDK1/iso:1/Phos:4
"A cyclin-dependent kinase 1 isoform 1 phosphorylated 4 in human. UniProtKB:P06493-1, Thr-14/Thr-161, MOD:00047|Tyr-15, MOD:00048." [PRO:DAN, Reactome:R-HSA-170071, Reactome:R-HSA-170074]

Yes
organism-sequence


PR:P06493-2
cyclin-dependent kinase 1 isoform h2 (human)
hCDK1/iso:h2
"A cyclin-dependent kinase 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P06493-2." [PRO:DNx, UniProtKB:P06493]

organism-modification


PR:000027126
cyclin-dependent kinase 1 phosphorylated form (human)
hCDK1/PhosRes+
"A cyclin-dependent kinase 1 phosphorylated form in human. UniProtKB:P06493, MOD:00696." [PRO:DAN]

organism-modification


PR:000026181
cyclin-dependent kinase 1 isoform 1 phosphorylated 1 (human)
hCDK1/iso:1/Phos:1
"A cyclin-dependent kinase 1 isoform 1 phosphorylated 1 in human. UniProtKB:P06493-1, Thr-14, MOD:00047." [PRO:CNA]

Yes
organism-modification


PR:000026211
cyclin-dependent kinase 1 isoform 1 phosphorylated 2 (human)
hCDK1/iso:1/Phos:2
"A cyclin-dependent kinase 1 isoform 1 phosphorylated 2 in human. UniProtKB:P06493-1, Thr-161, MOD:00047." [PRO:CNx, Reactome:R-HSA-157415, Reactome:R-HSA-170066]

Yes
organism-modification


PR:000027123
cyclin-dependent kinase 1 isoform 1 phosphorylated 3 (human)
hCDK1/iso:1/Phos:3
"A cyclin-dependent kinase 1 isoform 1 phosphorylated 3 in human. UniProtKB:P06493-1, Thr-14/Thr-161, MOD:00047." [PRO:DAN, Reactome:R-HSA-170078]

Yes
organism-modification


PR:000027124
cyclin-dependent kinase 1 isoform 1 phosphorylated 4 (human)
hCDK1/iso:1/Phos:4
"A cyclin-dependent kinase 1 isoform 1 phosphorylated 4 in human. UniProtKB:P06493-1, Thr-14/Thr-161, MOD:00047|Tyr-15, MOD:00048." [PRO:DAN, Reactome:R-HSA-170071, Reactome:R-HSA-170074]

Yes
organism-modification


PR:000064387
cyclin-dependent kinase 1 phosphorylated 1 (human)
hCDK1/Phos:1
"A cyclin-dependent kinase 1 (human) that has been phosphorylated on the residue at the position equivalent to Tyr-4 of the amino acid sequence represented by UniProtKB:P06493-1. Example: UniProtKB:P06493-1, Tyr-4, MOD:00048." [PRO:DNx, Reactome:R-HSA-9836187]

organism-modification


PR:000070341
cyclin-dependent kinase 1 phosphorylated 3 (human)
hCDK1/Phos:3
"A cyclin-dependent kinase 1 (human) that has been phosphorylated on the residues at the positions equivalent to Thr-14 and Thr-161 of the amino acid sequence represented by UniProtKB:P06493-1. Example: UniProtKB:P06493-1, Thr-14/Thr-161, MOD:00047." [PRO:DNx, Reactome:R-HSA-170078]

organism-modification


PR:000070409
cyclin-dependent kinase 1 phosphorylated 4 (human)
hCDK1/Phos:4
"A cyclin-dependent kinase 1 (human) that has been phosphorylated on the residues at the positions equivalent to Thr-14, Tyr-15, and Thr-161 of the amino acid sequence represented by UniProtKB:P06493-1. Example: UniProtKB:P06493-1, Thr-14/Thr-161, MOD:00047|Tyr-15, MOD:00048." [PRO:DNx, Reactome:R-HSA-170071, Reactome:R-HSA-170074]

organism-modification


PR:000070442
cyclin-dependent kinase 1 phosphorylated 5 (human)
hCDK1/Phos:5
"A cyclin-dependent kinase 1 (human) that has been phosphorylated on the residue at the position equivalent to Thr-161 of the amino acid sequence represented by UniProtKB:P06493-1. Example: UniProtKB:P06493-1, Thr-161, MOD:00047." [PRO:DNx, Reactome:R-HSA-157415, Reactome:R-HSA-170066]

organism-modification


PR:000071724
cyclin-dependent kinase 1 phosphorylated 2 (human)
hCDK1/Phos:2
"A cyclin-dependent kinase 1 (human) that has been phosphorylated on the residue at the position equivalent to Thr-14 of the amino acid sequence represented by UniProtKB:P06493-1. Example: UniProtKB:P06493-1, Thr-14, MOD:00047." [IEDB_epitope:2146939, PRO:DNx]

organism-modification


PR:000075851
cyclin-dependent kinase 1 hydroxylated 1 (human)
hCDK1/Hy:1
"A cyclin-dependent kinase 1 (human) that has been hydroxylated on the residue at the position equivalent to Trp-168 of the amino acid sequence represented by UniProtKB:P06493-1. Example: UniProtKB:P06493-1, Trp-168, MOD:01622." [IEDB_epitope:1325709, PRO:DNx]

organism-modification


PR:000080645
cyclin-dependent kinase 1 hydroxylated 2 (human)
hCDK1/Hy:2
"A cyclin-dependent kinase 1 (human) that has been hydroxylated on the residue at the position equivalent to Trp-244 of the amino acid sequence represented by UniProtKB:P06493-1. Example: UniProtKB:P06493-1, Trp-244, MOD:01622." [IEDB_epitope:1315669, PRO:DNx]

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hCDK1 forms found in complexes   

hCDK1 Component
 Complexes
PR:000026181 hCDK1/iso:1/Phos:1 PR:000027143 cyclin B1:Cdk1 complex phosphorylated 1 (human)
PR:000026211 hCDK1/iso:1/Phos:2 PR:000027144 cyclin B1:Cdk1 complex phosphorylated 2 (human)
PR:000027147 cyclin B1:Cdk1 complex phosphorylated 5 (human)
PR:000027148 cyclin B2:Cdk1 complex phosphorylated 1 (human)
PR:000027123 hCDK1/iso:1/Phos:3 PR:000027145 cyclin B1:Cdk1 complex phosphorylated 3 (human)
PR:000027149 cyclin B2:Cdk1 complex phosphorylated 2 (human)
PR:000027124 hCDK1/iso:1/Phos:4 PR:000027146 cyclin B1:Cdk1 complex phosphorylated 4 (human)