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Protein Ontology report - steroid 17-alpha-hydroxylase/17,20 lyase (human)
PR:P05093 -
http://purl.obolibrary.org/obo/PR_P05093
Protein Forms
Ontology Information
Show OBO stanza
/
GPI
PRO ID
PR:P05093
PRO name
steroid 17-alpha-hydroxylase/17,20 lyase (human)
Synonyms
PRO-Short-label
:
EXACT:
hCYP17A1
Gene-based
:
RELATED:
CYP17 | CYP17A1 | S17AH
Other
:
EXACT:
17-alpha-hydroxyprogesterone aldolase (human) | CYPXVII (human) | cytochrome P450 17A1 (human) | cytochrome P450-C17 (human) | cytochrome P450c17 (human) | steroid 17-alpha-monooxygenase (human)
Definition
"A cytochrome P450 17A1 that is encoded in the genome of human." [PRO:DNx,
UniProtKB:P05093
]
PRO Category
organism-gene
Parent
PR:000006099
cytochrome P450 17A1
PR:000029067
Homo sapiens protein
Gene Template
HGNC:2593
CYP17A1 (human)
Taxon
NCBITaxon:9606
Homo sapiens
Terms by PRO Category
Organism-Independent
Organism-Specific
Category
Number of Terms
Category
Number of Terms
Gene
0
Organism-Gene
1
Sequence
0
Organism-Sequence
7
Modification
0
Organism-Modification
1
Term Hierarchy
Visualization
DAG:
OLS:
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Related Cross References
Db identifiers
UniProtKB:P05093
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Protein Forms
Switch to
Compact View
Category
PRO ID
Name
Short Name
Definition
Ann.
Has Annotation?
Comp.
In Complex?
organism-gene
PR:P05093
steroid 17-alpha-hydroxylase/17,20 lyase (human)
hCYP17A1
"A cytochrome P450 17A1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P05093]
organism-sequence
PR:000060723
steroid 17-alpha-hydroxylase/17,20 lyase sequence variant R96Q (human)
hCYP17A1/var:R96Q
"A steroid 17-alpha-hydroxylase/17,20 lyase (human) that has a Gln residue at the position equivalent to Arg-96 of the amino acid sequence represented by UniProtKB:P05093. UniProtKB:P05093, Arg-96, CHEBI:30011." [PRO:DNx, Reactome:R-HSA-5601756]
organism-sequence
PR:000062498
steroid 17-alpha-hydroxylase/17,20 lyase sequence variant W406R (human)
hCYP17A1/var:W406R
"A steroid 17-alpha-hydroxylase/17,20 lyase (human) that has an Arg residue at the position equivalent to Trp-406 of the amino acid sequence represented by UniProtKB:P05093. UniProtKB:P05093, Trp-406, CHEBI:29952." [PRO:DNx, Reactome:R-HSA-5601826]
organism-sequence
PR:000063111
steroid 17-alpha-hydroxylase/17,20 lyase sequence variant S106P (human)
hCYP17A1/var:S106P
"A steroid 17-alpha-hydroxylase/17,20 lyase (human) that has a Pro residue at the position equivalent to Ser-106 of the amino acid sequence represented by UniProtKB:P05093. UniProtKB:P05093, Ser-106, CHEBI:50342." [PRO:DNx, Reactome:R-HSA-5601769]
organism-sequence
PR:000063400
steroid 17-alpha-hydroxylase/17,20 lyase sequence variant R362C (human)
hCYP17A1/var:R362C
"A steroid 17-alpha-hydroxylase/17,20 lyase (human) that has a Cys residue at the position equivalent to Arg-362 of the amino acid sequence represented by UniProtKB:P05093. UniProtKB:P05093, Arg-362, CHEBI:29950." [PRO:DNx, Reactome:R-HSA-5601794]
organism-sequence
PR:000064025
steroid 17-alpha-hydroxylase/17,20 lyase sequence variant R347H (human)
hCYP17A1/var:R347H
"A steroid 17-alpha-hydroxylase/17,20 lyase (human) that has a His residue at the position equivalent to Arg-347 of the amino acid sequence represented by UniProtKB:P05093. UniProtKB:P05093, Arg-347, CHEBI:29979." [PRO:DNx, Reactome:R-HSA-5601786]
organism-sequence
PR:000064510
steroid 17-alpha-hydroxylase/17,20 lyase sequence variant R358Q (human)
hCYP17A1/var:R358Q
"A steroid 17-alpha-hydroxylase/17,20 lyase (human) that has a Gln residue at the position equivalent to Arg-358 of the amino acid sequence represented by UniProtKB:P05093. UniProtKB:P05093, Arg-358, CHEBI:30011." [PRO:DNx, Reactome:R-HSA-5601823]
organism-sequence
PR:000064596
steroid 17-alpha-hydroxylase/17,20 lyase sequence variant R96W (human)
hCYP17A1/var:R96W
"A steroid 17-alpha-hydroxylase/17,20 lyase (human) that has a Trp residue at the position equivalent to Arg-96 of the amino acid sequence represented by UniProtKB:P05093. UniProtKB:P05093, Arg-96, CHEBI:29954." [PRO:DNx, Reactome:R-HSA-5601803]
organism-modification
PR:000045639
steroid 17-alpha-hydroxylase/17,20 lyase phosphorylated 1 (human)
hCYP17A1/Phos:1
"A steroid 17-alpha-hydroxylase/17,20 lyase (human) that has been phosphorylated at Ser-258. UniProtKB:P05093, Ser-258, MOD:00046." [iPTMnet:P05093, PMID:20160131]