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Protein Ontology report - steroid 17-alpha-hydroxylase/17,20 lyase (human)
PR:P05093 - http://purl.obolibrary.org/obo/PR_P05093
 
  Protein Forms      
Ontology Information Show OBO stanza / GPI
  PRO ID
PR:P05093   
  PRO namesteroid 17-alpha-hydroxylase/17,20 lyase (human) 
  Synonyms
PRO-Short-label: EXACT:hCYP17A1
Gene-based: RELATED:CYP17 | CYP17A1 | S17AH
Other: EXACT:17-alpha-hydroxyprogesterone aldolase (human) | CYPXVII (human) | cytochrome P450 17A1 (human) | cytochrome P450-C17 (human) | cytochrome P450c17 (human) | steroid 17-alpha-monooxygenase (human)
  Definition"A cytochrome P450 17A1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P05093
  PRO Categoryorganism-gene 
  ParentPR:000006099 cytochrome P450 17A1
PR:000029067 Homo sapiens protein
  Gene TemplateHGNC:2593 CYP17A1 (human)
  TaxonNCBITaxon:9606 Homo sapiens
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene0                                                  Organism-Gene 1                                        
         Sequence0                                                  Organism-Sequence 7                                        
         Modification0                                                  Organism-Modification 1                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:P05093
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
organism-gene



PR:P05093

steroid 17-alpha-hydroxylase/17,20 lyase (human)

hCYP17A1


"A cytochrome P450 17A1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P05093]


organism-sequence



PR:000060723

steroid 17-alpha-hydroxylase/17,20 lyase sequence variant R96Q (human)

hCYP17A1/var:R96Q


"A steroid 17-alpha-hydroxylase/17,20 lyase (human) that has a Gln residue at the position equivalent to Arg-96 of the amino acid sequence represented by UniProtKB:P05093. UniProtKB:P05093, Arg-96, CHEBI:30011." [PRO:DNx, Reactome:R-HSA-5601756]


organism-sequence



PR:000062498

steroid 17-alpha-hydroxylase/17,20 lyase sequence variant W406R (human)

hCYP17A1/var:W406R


"A steroid 17-alpha-hydroxylase/17,20 lyase (human) that has an Arg residue at the position equivalent to Trp-406 of the amino acid sequence represented by UniProtKB:P05093. UniProtKB:P05093, Trp-406, CHEBI:29952." [PRO:DNx, Reactome:R-HSA-5601826]


organism-sequence



PR:000063111

steroid 17-alpha-hydroxylase/17,20 lyase sequence variant S106P (human)

hCYP17A1/var:S106P


"A steroid 17-alpha-hydroxylase/17,20 lyase (human) that has a Pro residue at the position equivalent to Ser-106 of the amino acid sequence represented by UniProtKB:P05093. UniProtKB:P05093, Ser-106, CHEBI:50342." [PRO:DNx, Reactome:R-HSA-5601769]


organism-sequence



PR:000063400

steroid 17-alpha-hydroxylase/17,20 lyase sequence variant R362C (human)

hCYP17A1/var:R362C


"A steroid 17-alpha-hydroxylase/17,20 lyase (human) that has a Cys residue at the position equivalent to Arg-362 of the amino acid sequence represented by UniProtKB:P05093. UniProtKB:P05093, Arg-362, CHEBI:29950." [PRO:DNx, Reactome:R-HSA-5601794]


organism-sequence



PR:000064025

steroid 17-alpha-hydroxylase/17,20 lyase sequence variant R347H (human)

hCYP17A1/var:R347H


"A steroid 17-alpha-hydroxylase/17,20 lyase (human) that has a His residue at the position equivalent to Arg-347 of the amino acid sequence represented by UniProtKB:P05093. UniProtKB:P05093, Arg-347, CHEBI:29979." [PRO:DNx, Reactome:R-HSA-5601786]


organism-sequence



PR:000064510

steroid 17-alpha-hydroxylase/17,20 lyase sequence variant R358Q (human)

hCYP17A1/var:R358Q


"A steroid 17-alpha-hydroxylase/17,20 lyase (human) that has a Gln residue at the position equivalent to Arg-358 of the amino acid sequence represented by UniProtKB:P05093. UniProtKB:P05093, Arg-358, CHEBI:30011." [PRO:DNx, Reactome:R-HSA-5601823]


organism-sequence



PR:000064596

steroid 17-alpha-hydroxylase/17,20 lyase sequence variant R96W (human)

hCYP17A1/var:R96W


"A steroid 17-alpha-hydroxylase/17,20 lyase (human) that has a Trp residue at the position equivalent to Arg-96 of the amino acid sequence represented by UniProtKB:P05093. UniProtKB:P05093, Arg-96, CHEBI:29954." [PRO:DNx, Reactome:R-HSA-5601803]


organism-modification



PR:000045639

steroid 17-alpha-hydroxylase/17,20 lyase phosphorylated 1 (human)

hCYP17A1/Phos:1


"A steroid 17-alpha-hydroxylase/17,20 lyase (human) that has been phosphorylated at Ser-258. UniProtKB:P05093, Ser-258, MOD:00046." [iPTMnet:P05093, PMID:20160131]