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Protein Ontology report - c-myc protein isoform 1 (human)
PR:P01106-1 - http://purl.obolibrary.org/obo/PR_P01106-1
 
  Protein Forms  Complex  Annotations      
Ontology Information Show OBO stanza / PAF / GPI
  PRO ID
PR:P01106-1   
  PRO namec-myc protein isoform 1 (human) 
  Synonyms
PRO-Short-label: EXACT:hMYC/iso:1
  Definition"A c-myc protein isoform 1 that is encoded in the genome of human." [PRO:CNA] 
  PRO Categoryorganism-sequence 
  ParentPR:000000228 c-myc protein isoform 1
PR:P01106 Myc proto-oncogene protein (human)
  TaxonNCBITaxon:9606 Homo sapiens
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Sequence0                                                  Organism-Sequence 1                                        
         Modification0                                                  Organism-Modification 7                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:P01106-1
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

Comp. In Complex?
organism-sequence


PR:P01106-1
c-myc protein isoform 1 (human)
hMYC/iso:1
"A c-myc protein isoform 1 that is encoded in the genome of human." [PRO:CNA]
Yes
organism-modification


PR:000026033
c-myc protein isoform 1 acetylated 1 (human)
hMYC/iso:1/Ac:1
"A c-myc protein isoform 1 acetylated 1 in human. UniProtKB:P01106-1, Lys-143/Lys-157/Lys-275/Lys-317/Lys-323/Lys-371, MOD:02078." [PMID:16126174]
Yes
Yes
organism-modification


PR:000026038
c-myc protein isoform 1 unmodified form (human)
hMYC/iso:1/UnMod
"A c-myc protein isoform 1 unmodified form in human." [PMID:15003254, PRO:CNA]

Yes
organism-modification


PR:000026041
c-myc protein isoform 1 phosphorylated 4 (human)
hMYC/iso:1/Phos:4
"A c-myc protein isoform 1 phosphorylated 4 in human. UniProtKB:P01106-1, Thr-58, MOD:00047." [PMID:19131971]

organism-modification


PR:000026051
c-myc protein isoform 1 O-glycosylated 1 (human)
hMYC/iso:1/OGlyco:1
"A c-myc protein isoform 1 O-glycosylated 1 in human. UniProtKB:P01106-1, Thr-58, MOD:00806." [PMID:11904304, PMID:7642555]
Yes
organism-modification


PR:000026054
c-myc protein isoform 1 phosphorylated 2 (human)
hMYC/iso:1/Phos:2
"A c-myc protein isoform 1 phosphorylated 2 in human. UniProtKB:P01106-1, Thr-58, MOD:00047|Ser-62, MOD:00046." [PMID:7623799]
Yes
organism-modification


PR:000026055
c-myc protein isoform 1 phosphorylated 3 (human)
hMYC/iso:1/Phos:3
"A c-myc protein isoform 1 phosphorylated 3 in human. UniProtKB:P01106-1, Ser-62/Ser-71, MOD:00046." [PMID:12676581]
Yes
organism-modification


PR:000036448
c-myc protein isoform 1 phosphorylated 1 (human)
hMYC/iso:1/Phos:1
"A c-myc protein isoform 1 phosphorylated 1 in human. UniProtKB:P01106-1, Ser-62, MOD:00046." [PMID:19131971, PRO:CNA]
Yes
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hMYC/iso:1 forms found in complexes   

hMYC/iso:1 Component
 Complexes
PR:000026033 hMYC/iso:1/Ac:1 PR:000026035 Myc-max acetylated complex (human)
PR:000026038 hMYC/iso:1/UnMod PR:000026039 Myc-max complex 1 (human)
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Functional Annotation (GO-centric view) Switch to PRO Centric View     

Biological Process GO Term
Protein Forms & Complexes
Evidence
GO:0006357 regulation of transcription by RNA polymerase IIPR:000026051 hMYC/iso:1/OGlyco:1 PMID:11904304
PR:P01106-1 hMYC/iso:1 PMID:16908182; PMID:2006410
GO:0008283 cell population proliferationPR:P01106-1 hMYC/iso:1 PMID:10962037
GO:0045766 positive regulation of angiogenesisPR:000026055 hMYC/iso:1/Phos:3 PMID:12676581
GO:0051726 regulation of cell cyclePR:P01106-1 hMYC/iso:1 PMID:10962037

Molecular Function GO Term
Protein Forms & Complexes
Evidence
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specificPR:000026051 hMYC/iso:1/OGlyco:1 PMID:11904304
GO:0003700 DNA-binding transcription factor activityPR:000026033 hMYC/iso:1/Ac:1 PMID:16126174
contributes_to GO:0003700 DNA-binding transcription factor activityPR:P01106-1 hMYC/iso:1 PMID:16908182; PMID:2006410
NOT GO:0003700 DNA-binding transcription factor activityPR:000026054 hMYC/iso:1/Phos:2 PMID:7623799
GO:0005515 protein bindingPR:000036448 hMYC/iso:1/Phos:1 PMID:19131971
PR:P01106-1 hMYC/iso:1 PMID:12706874

Cellular Location GO Term
Protein Forms & Complexes
Evidence
GO:0005634 nucleusPR:000026033 hMYC/iso:1/Ac:1 PMID:16126174
PR:000026055 hMYC/iso:1/Phos:3 PMID:12676581
GO:0005667 transcription factor complexPR:000026033 hMYC/iso:1/Ac:1 PMID:16126174
PR:P01106-1 hMYC/iso:1 PMID:16908182; PMID:2006410