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Protein Ontology report - serine/threonine-protein kinase/endoribonuclease IRE1 (human)
PR:O75460 - http://purl.obolibrary.org/obo/PR_O75460
 
  Protein Forms      
Ontology Information Show OBO stanza / GPI
  PRO ID
PR:O75460   
  PRO nameserine/threonine-protein kinase/endoribonuclease IRE1 (human) 
  Synonyms
PRO-Short-label: EXACT:hERN1
Gene-based: RELATED:ERN1 | IRE1
Other: EXACT:endoplasmic reticulum-to-nucleus signaling 1 (human) | hIRE1p | inositol-requiring protein 1 (human) | Ire1-alpha (human) | IRE1a (human)
  Definition"A serine/threonine-protein kinase/endoribonuclease IRE1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:O75460
  PRO Categoryorganism-gene 
  ParentPR:000007185 serine/threonine-protein kinase/endoribonuclease IRE1
PR:000029067 Homo sapiens protein
  Gene TemplateHGNC:3449 ERN1 (human)
  TaxonNCBITaxon:9606 Homo sapiens
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene0                                                  Organism-Gene 1                                        
         Sequence0                                                  Organism-Sequence 2                                        
         Modification0                                                  Organism-Modification 5                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:O75460
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
organism-gene



PR:O75460

serine/threonine-protein kinase/endoribonuclease IRE1 (human)

hERN1


"A serine/threonine-protein kinase/endoribonuclease IRE1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:O75460]


organism-sequence



PR:O75460-1

serine/threonine-protein kinase/endoribonuclease IRE1 isoform h1 (human)

hERN1/iso:h1


"A serine/threonine-protein kinase/endoribonuclease IRE1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O75460-1." [PRO:DNx, UniProtKB:O75460]


organism-sequence



PR:O75460-2

serine/threonine-protein kinase/endoribonuclease IRE1 isoform h2 (human)

hERN1/iso:h2


"A serine/threonine-protein kinase/endoribonuclease IRE1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O75460-2." [PRO:DNx, UniProtKB:O75460]


organism-modification



PR:000063166

serine/threonine-protein kinase/endoribonuclease IRE1, signal peptide removed form (human)

hERN1/SigPep-


"A serine/threonine-protein kinase/endoribonuclease IRE1 (human) that has had the signal peptide removed. Example: UniProtKB:O75460-1, 19-977." [PRO:DNx, Reactome:R-HSA-381076]


organism-modification



PR:000063683

serine/threonine-protein kinase/endoribonuclease IRE1, signal peptide removed phosphorylated 1 (human)

hERN1/SigPep-/Phos:1


"A serine/threonine-protein kinase/endoribonuclease IRE1 (human) that has had the signal peptide removed and that has been phosphorylated on the residue at the position equivalent to Ser-724 of the amino acid sequence represented by UniProtKB:O75460-1. Example: UniProtKB:O75460-1, 19-977, Ser-724, MOD:00046." [PRO:DNx, Reactome:R-HSA-381029]


organism-modification



PR:000073719

serine/threonine-protein kinase/endoribonuclease IRE1 cysteinylated 1 (human)

hERN1/Cyst:1


"A serine/threonine-protein kinase/endoribonuclease IRE1 (human) that has been cysteinylated on the residue at the position equivalent to Cys-630 of the amino acid sequence represented by UniProtKB:O75460-1. Example: UniProtKB:O75460-1, Cys-630, MOD:00765." [IEDB_epitope:924964, PRO:DNx]


organism-modification



PR:000078305

serine/threonine-protein kinase/endoribonuclease IRE1 deaminated 1 (human)

hERN1/Deam:1


"A serine/threonine-protein kinase/endoribonuclease IRE1 (human) that has been deaminated on the residue at the position equivalent to Gln-475 of the amino acid sequence represented by UniProtKB:O75460-1. Example: UniProtKB:O75460-1, Gln-475, MOD:00685." [IEDB_epitope:1584799, PRO:DNx]


organism-modification



PR:000078501

serine/threonine-protein kinase/endoribonuclease IRE1 deaminated 2 (human)

hERN1/Deam:2


"A serine/threonine-protein kinase/endoribonuclease IRE1 (human) that has been deaminated on the residue at the position equivalent to Gln-473 of the amino acid sequence represented by UniProtKB:O75460-1. Example: UniProtKB:O75460-1, Gln-473, MOD:00685." [IEDB_epitope:1584798, PRO:DNx]