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Protein Ontology report - serine/threonine-protein kinase Chk1 (human)
PR:O14757 - http://purl.obolibrary.org/obo/PR_O14757
 
  Protein Forms      
Ontology Information Show OBO stanza / GPI
  PRO ID
PR:O14757   
  PRO nameserine/threonine-protein kinase Chk1 (human) 
  Synonyms
PRO-Short-label: EXACT:hCHEK1
Gene-based: RELATED:CHEK1 | CHK1
Other: EXACT:cell cycle checkpoint kinase (human) | checkpoint kinase-1 (human) | CHK1 checkpoint homolog (human)
  Definition"A serine/threonine-protein kinase Chk1 that is encoded in the genome of human." [PRO:CNA] 
  PRO Categoryorganism-gene 
  ParentPR:000005417 serine/threonine-protein kinase Chk1
PR:000029067 Homo sapiens protein
  Gene TemplateHGNC:1925 CHEK1 (human)
  TaxonNCBITaxon:9606 Homo sapiens
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene0                                                  Organism-Gene 1                                        
         Sequence0                                                  Organism-Sequence 3                                        
         Modification0                                                  Organism-Modification 6                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:O14757
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
organism-gene



PR:O14757

serine/threonine-protein kinase Chk1 (human)

hCHEK1


"A serine/threonine-protein kinase Chk1 that is encoded in the genome of human." [PRO:CNA]


organism-sequence



PR:O14757-1

serine/threonine-protein kinase Chk1 isoform 1 (human)

hCHEK1/iso:1


"A serine/threonine-protein kinase Chk1 isoform 1 that is encoded in the genome of human." [PRO:DNx]


organism-sequence



PR:O14757-2

serine/threonine-protein kinase Chk1 isoform 2 (human)

hCHEK1/iso:2


"A serine/threonine-protein kinase Chk1 isoform 2 that is encoded in the genome of human." [PRO:DNx]


organism-sequence



PR:O14757-3

serine/threonine-protein kinase Chk1 isoform h3 (human)

hCHEK1/iso:h3


"A serine/threonine-protein kinase Chk1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O14757-3." [PRO:DNx, UniProtKB:O14757]


organism-modification



PR:000045568

serine/threonine-protein kinase Chk1 phosphorylated 1 (human)

hCHEK1/Phos:1


"A serine/threonine-protein kinase Chk1 (human) that has been phosphorylated on the residue at the position equivalent to Ser-345 of the amino acid sequence represented by UniProtKB:O14757-1. Example: UniProtKB:O14757-1, Ser-345, MOD:00046." [iPTMnet:O14757, PMID:10859164, PMID:14681223, PMID:15533933]


organism-modification



PR:000046701

serine/threonine-protein kinase Chk1 phosphorylated 2 (human)

hCHEK1/Phos:2


"A serine/threonine-protein kinase Chk1 (human) that has been post-translationally modified to include phosphoserine at positions 317 and 345 of the amino acid sequence represented by UniProtKB:O14757. UniProtKB:O14757, Ser-317/Ser-345, MOD:00046." [PRO:DNx, Reactome:R-HSA-113838]


organism-modification



PR:000071876

serine/threonine-protein kinase Chk1 deaminated 1 (human)

hCHEK1/Deam:1


"A serine/threonine-protein kinase Chk1 (human) that has been deaminated on the residue at the position equivalent to Asn-135 of the amino acid sequence represented by UniProtKB:O14757-1. Example: UniProtKB:O14757-1, Asn-135, MOD:00684." [IEDB_epitope:1564062, PRO:DNx]


organism-modification



PR:000073649

serine/threonine-protein kinase Chk1 methylated 1 (human)

hCHEK1/Me:1


"A serine/threonine-protein kinase Chk1 (human) that has been methylated on the residue at the position equivalent to Cys-349 of the amino acid sequence represented by UniProtKB:O14757-1. Example: UniProtKB:O14757-1, Cys-349, MOD:00660." [IEDB_epitope:1038944, PRO:DNx]


organism-modification



PR:000076757

serine/threonine-protein kinase Chk1 methylated 2 (human)

hCHEK1/Me:2


"A serine/threonine-protein kinase Chk1 (human) that has been methylated on the residue at the position equivalent to Cys-408 of the amino acid sequence represented by UniProtKB:O14757-1. Example: UniProtKB:O14757-1, Cys-408, MOD:00660." [IEDB_epitope:1026404, PRO:DNx]


organism-modification



PR:000078276

serine/threonine-protein kinase Chk1 phosphorylated 3 (human)

hCHEK1/Phos:3


"A serine/threonine-protein kinase Chk1 (human) that has been phosphorylated on the residue at the position equivalent to Ser-467 of the amino acid sequence represented by UniProtKB:O14757-1. Example: UniProtKB:O14757-1, Ser-467, MOD:00046." [IEDB_epitope:1319645, PRO:DNx]