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Protein Ontology report - bone morphogenetic protein 4, mature form (human)
PR:000072771 - http://purl.obolibrary.org/obo/PR_000072771
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza / GPI
  PRO ID
PR:000072771   
  PRO namebone morphogenetic protein 4, mature form (human) 
  Synonyms
PRO-Short-label: EXACT:hBMP4/mature
PRO-proteoform-std: EXACT:UniProtKB:P12644, 293-408
Reactome-displayName: RELATED:BMP4
  Definition"A bone morphogenetic protein 4 (human) that has had the signal peptide and propeptide removed. UniProtKB:P12644, 293-408." [PRO:DNx, Reactome:R-HSA-8858573, Reactome:R-HSA-8956775] 
  PRO Categoryorganism-modification 
  ParentPR:000046492 bone morphogenetic protein 4, signal peptide removed form (human)
PR:P12644 bone morphogenetic protein 4 (human)
  TaxonNCBITaxon:9606 Homo sapiens
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Modification0                                                  Organism-Modification 3                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

Comp. In Complex?
organism-modification


PR:000072771 bone morphogenetic protein 4, mature form (human)
hBMP4/mature

organism-modification


PR:000036511 bone morphogenetic protein 4 isoform 1, mature form (human)
hBMP4/iso:1/mature
Yes
organism-modification


PR:000072824 bone morphogenetic protein 4, mature phosphorylated form (human)
hBMP4/mature/PhosRes+

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Functional Annotation (GO-centric view) Switch to PRO Centric View     

Biological Process GO Term
Protein Forms & Complexes
Evidence
GO:0001649 osteoblast differentiationPR:000036511 hBMP4/iso:1/mature PMID:14749725
GO:0001657 ureteric bud developmentPR:000036511 hBMP4/iso:1/mature PMID:12141440
GO:0001934 positive regulation of protein phosphorylationPR:000036511 hBMP4/iso:1/mature PMID:14749725
GO:0007498 mesoderm developmentPR:000036511 hBMP4/iso:1/mature PMID:9804553
GO:0030509 BMP signaling pathwayPR:000036511 hBMP4/iso:1/mature PMID:12805376

Molecular Function GO Term
Protein Forms & Complexes
Evidence
GO:0005102 signaling receptor bindingPR:000036511 hBMP4/iso:1/mature PMID:11401399; PMID:14660436
GO:0042803 protein homodimerization activityPR:000036511 hBMP4/iso:1/mature PMID:12805376

Cellular Location GO Term
Protein Forms & Complexes
Evidence
GO:0005615 extracellular spacePR:000036511 hBMP4/iso:1/mature PMID:12805376