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Protein Ontology report - serine/threonine-protein kinase B-raf, initiator methionine removed phosphoserine and phosphothreonine form (human)
PR:000063053 -
http://purl.obolibrary.org/obo/PR_000063053
Protein Forms
Ontology Information
Show OBO stanza
/
GPI
PRO ID
PR:000063053
PRO name
serine/threonine-protein kinase B-raf, initiator methionine removed phosphoserine and phosphothreonine form (human)
Synonyms
PRO-Short-label
:
EXACT:
hBRAF/InitMet-/pSerThr+
PRO-proteoform-std
:
EXACT:
UniProtKB:P15056
, 2-766,
MOD:00046
|
MOD:00047
Reactome-displayName
:
RELATED:
p-S,T-BRAF
Definition
"A serine/threonine-protein kinase B-raf (human) that has had the initiator methionine removed and that includes at least one phosphorylated serine and at least one phosphorylated threonine.
UniProtKB:P15056
, 2-766,
MOD:00046
|
MOD:00047
." [PRO:DNx,
Reactome:R-HSA-169856
]
PRO Category
organism-modification
Parent
PR:000037070
phosphoprotein
PR:000046505
serine/threonine-protein kinase B-raf, initiator methionine removed form (human)
PR:P15056
serine/threonine-protein kinase B-raf (human)
Taxon
NCBITaxon:9606
Homo sapiens
Terms by PRO Category
Organism-Independent
Organism-Specific
Category
Number of Terms
Category
Number of Terms
Modification
0
Organism-Modification
21
Term Hierarchy
Visualization
DAG:
OLS:
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Protein Forms
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Category
PRO ID
Name
Short Name
Definition
Ann.
Has Annotation?
Comp.
In Complex?
organism-modification
PR:000063053
serine/threonine-protein kinase B-raf, initiator methionine removed phosphoserine and phosphothreonine form (human)
hBRAF/InitMet-/pSerThr+
"A serine/threonine-protein kinase B-raf (human) that has had the initiator methionine removed and that includes at least one phosphorylated serine and at least one phosphorylated threonine. UniProtKB:P15056, 2-766, MOD:00046|MOD:00047." [PRO:DNx, Reactome:R-HSA-169856]
organism-modification
PR:000046506
serine/threonine-protein kinase B-raf, initiator methionine removed phosphorylated 2 (human)
hBRAF/InitMet-/Phos:2
"A serine/threonine-protein kinase B-raf (human) that has had the initiator methionine removed and has been post-translationally modified to include phosphoserine at positions 151, 446, 602, 729, and 750, and phosphothreonine at positions 401, 599 and 753 of the amino acid sequence represented by UniProtKB:P15056. UniProtKB:P15056, 2-766, Ser-151/Ser-446/Ser-602/Ser-729/Ser-750, MOD:00046|Thr-401/Thr-599/Thr-753, MOD:00047." [PRO:DAN, Reactome:R-HSA-5675199]
organism-modification
PR:000046509
serine/threonine-protein kinase B-raf, initiator methionine removed phosphorylated 5 (human)
hBRAF/InitMet-/Phos:5
"A serine/threonine-protein kinase B-raf (human) that has had the initiator methionine removed and has been post-translationally modified to include phosphoserine at positions 446, 602 and 729, and phosphothreonine at position 599 of the amino acid sequence represented by UniProtKB:P15056. UniProtKB:P15056, 2-766, Ser-446/Ser-602/Ser-729, MOD:00046|Thr-599, MOD:00047." [PRO:DAN, Reactome:R-HSA-5672676, Reactome:R-HSA-5672679]
organism-modification
PR:000060383
serine/threonine-protein kinase B-raf sequence variant L597Q, initiator methionine removed phosphorylated 1 (human)
hBRAF/var:L597Q/InitMet-/Phos:1
"A serine/threonine-protein kinase B-raf (human) that has a Gln residue at the position equivalent to Leu-597 of the amino acid sequence represented by UniProtKB:P15056, that has had the initiator methionine removed, and that has been phosphorylated on the residues at the positions equivalent to Ser-446, Thr-599, Ser-602, and Ser-729. UniProtKB:P15056, 2-766, Ser-446/Ser-602/Ser-729, MOD:00046|Leu-597, CHEBI:30011|Thr-599, MOD:00047." [PRO:DNx, Reactome:R-HSA-9648630]
organism-modification
PR:000060413
serine/threonine-protein kinase B-raf sequence variant L597R, initiator methionine removed phosphorylated 1 (human)
hBRAF/var:L597R/InitMet-/Phos:1
"A serine/threonine-protein kinase B-raf (human) that has an Arg residue at the position equivalent to Leu-597 of the amino acid sequence represented by UniProtKB:P15056, that has had the initiator methionine removed, and that has been phosphorylated on the residues at the positions equivalent to Ser-446, Thr-599, Ser-602, and Ser-729. UniProtKB:P15056, 2-766, Ser-446/Ser-602/Ser-729, MOD:00046|Leu-597, CHEBI:29952|Thr-599, MOD:00047." [PRO:DNx, Reactome:R-HSA-9648631]
organism-modification
PR:000060589
serine/threonine-protein kinase B-raf sequence variant F595L, initiator methionine removed phosphorylated 1 (human)
hBRAF/var:F595L/InitMet-/Phos:1
"A serine/threonine-protein kinase B-raf (human) that has a Leu residue at the position equivalent to Phe-595 of the amino acid sequence represented by UniProtKB:P15056, that has had the initiator methionine removed, and that has been phosphorylated on the residues at the positions equivalent to Ser-446, Thr-599, Ser-602, and Ser-729. UniProtKB:P15056, 2-766, Ser-446/Ser-602/Ser-729, MOD:00046|Phe-595, CHEBI:30006|Thr-599, MOD:00047." [PRO:DNx, Reactome:R-HSA-8936641]
organism-modification
PR:000060702
serine/threonine-protein kinase B-raf sequence variant G464E, initiator methionine removed phosphorylated 1 (human)
hBRAF/var:G464E/InitMet-/Phos:1
"A serine/threonine-protein kinase B-raf (human) that has a Glu residue at the position equivalent to Gly-464 of the amino acid sequence represented by UniProtKB:P15056, that has had the initiator methionine removed, and that has been phosphorylated on the residues at the positions equivalent to Ser-446, Thr-599, Ser-602, and Ser-729. UniProtKB:P15056, 2-766, Ser-446/Ser-602/Ser-729, MOD:00046|Gly-464, CHEBI:29972|Thr-599, MOD:00047." [PRO:DNx, Reactome:R-HSA-8936645]
organism-modification
PR:000060923
serine/threonine-protein kinase B-raf sequence variant V600K, initiator methionine removed phosphorylated 1 (human)
hBRAF/var:V600K/InitMet-/Phos:1
"A serine/threonine-protein kinase B-raf (human) that has a Lys residue at the position equivalent to Val-600 of the amino acid sequence represented by UniProtKB:P15056, that has had the initiator methionine removed, and that has been phosphorylated on the residues at the positions equivalent to Ser-446, Thr-599, Ser-602, and Ser-729. UniProtKB:P15056, 2-766, Ser-446/Ser-602/Ser-729, MOD:00046|Thr-599, MOD:00047|Val-600, CHEBI:29967." [PRO:DNx, Reactome:R-HSA-8936651]
organism-modification
PR:000061019
serine/threonine-protein kinase B-raf sequence variant G464V, initiator methionine removed phosphorylated 1 (human)
hBRAF/var:G464V/InitMet-/Phos:1
"A serine/threonine-protein kinase B-raf (human) that has a Val residue at the position equivalent to Gly-464 of the amino acid sequence represented by UniProtKB:P15056, that has had the initiator methionine removed, and that has been phosphorylated on the residues at the positions equivalent to Ser-446, Thr-599, Ser-602, and Ser-729. UniProtKB:P15056, 2-766, Ser-446/Ser-602/Ser-729, MOD:00046|Gly-464, CHEBI:30015|Thr-599, MOD:00047." [PRO:DNx, Reactome:R-HSA-9648633]
organism-modification
PR:000061303
serine/threonine-protein kinase B-raf sequence variant G466V, initiator methionine removed phosphorylated 2 (human)
hBRAF/var:G466V/InitMet-/Phos:2
"A serine/threonine-protein kinase B-raf (human) that has a Val residue at the position equivalent to Gly-466 of the amino acid sequence represented by UniProtKB:P15056, that has had the initiator methionine removed, and that has been phosphorylated on the residues at the positions equivalent to Ser-446, Thr-599, Ser-602, and Ser-729. UniProtKB:P15056, 2-766, Ser-446/Ser-602/Ser-729, MOD:00046|Gly-466, CHEBI:30015|Thr-599, MOD:00047." [PRO:DNx, Reactome:R-HSA-9648859]
organism-modification
PR:000061820
serine/threonine-protein kinase B-raf sequence variant T244P, initiator methionine removed phosphorylated 1 (human)
hBRAF/var:T244P/InitMet-/Phos:1
"A serine/threonine-protein kinase B-raf (human) that has a Pro residue at the position equivalent to Thr-244 of the amino acid sequence represented by UniProtKB:P15056, that has had the initiator methionine removed, and that has been phosphorylated on the residues at the positions equivalent to Ser-446, Thr-599, Ser-602, and Ser-729. UniProtKB:P15056, 2-766, Thr-244, CHEBI:50342|Ser-446/Ser-602/Ser-729, MOD:00046|Thr-599, MOD:00047." [PRO:DNx, Reactome:R-HSA-9651194]
organism-modification
PR:000063068
serine/threonine-protein kinase B-raf sequence variant L597V, initiator methionine removed phosphorylated 2 (human)
hBRAF/var:L597V/InitMet-/Phos:2
"A serine/threonine-protein kinase B-raf (human) that has a Val residue at the position equivalent to Leu-597 of the amino acid sequence represented by UniProtKB:P15056, that has had the initiator methionine removed, and that has been phosphorylated on the residues at the positions equivalent to Ser-446, Thr-599, Ser-602, and Ser-729. UniProtKB:P15056, 2-766, Ser-446/Ser-602/Ser-729, MOD:00046|Leu-597, CHEBI:30015|Thr-599, MOD:00047." [PRO:DNx, Reactome:R-HSA-8936647]
organism-modification
PR:000063374
serine/threonine-protein kinase B-raf sequence variant A246P, initiator methionine removed phosphorylated 1 (human)
hBRAF/var:A246P/InitMet-/Phos:1
"A serine/threonine-protein kinase B-raf (human) that has a Pro residue at the position equivalent to Ala-246 of the amino acid sequence represented by UniProtKB:P15056, that has had the initiator methionine removed, and that has been phosphorylated on the residues at the positions equivalent to Ser-446, Thr-599, Ser-602, and Ser-729. UniProtKB:P15056, 2-766, Ala-246, CHEBI:50342|Ser-446/Ser-602/Ser-729, MOD:00046|Thr-599, MOD:00047." [PRO:DNx, Reactome:R-HSA-9651188]
organism-modification
PR:000063576
serine/threonine-protein kinase B-raf sequence variant G469R, initiator methionine removed phosphorylated 2 (human)
hBRAF/var:G469R/InitMet-/Phos:2
"A serine/threonine-protein kinase B-raf (human) that has an Arg residue at the position equivalent to Gly-469 of the amino acid sequence represented by UniProtKB:P15056, that has had the initiator methionine removed, and that has been phosphorylated on the residues at the positions equivalent to Ser-446, Thr-599, Ser-602, and Ser-729. UniProtKB:P15056, 2-766, Ser-446/Ser-602/Ser-729, MOD:00046|Gly-469, CHEBI:29952|Thr-599, MOD:00047." [PRO:DNx, Reactome:R-HSA-9648627]
organism-modification
PR:000063597
serine/threonine-protein kinase B-raf sequence variant G469V, initiator methionine removed phosphorylated 2 (human)
hBRAF/var:G469V/InitMet-/Phos:2
"A serine/threonine-protein kinase B-raf (human) that has a Val residue at the position equivalent to Gly-469 of the amino acid sequence represented by UniProtKB:P15056, that has had the initiator methionine removed, and that has been phosphorylated on the residues at the positions equivalent to Ser-446, Thr-599, Ser-602, and Ser-729. UniProtKB:P15056, 2-766, Ser-446/Ser-602/Ser-729, MOD:00046|Gly-469, CHEBI:30015|Thr-599, MOD:00047." [PRO:DNx, Reactome:R-HSA-9648628]
organism-modification
PR:000063699
serine/threonine-protein kinase B-raf sequence variant N581S, initiator methionine removed phosphorylated 1 (human)
hBRAF/var:N581S/InitMet-/Phos:1
"A serine/threonine-protein kinase B-raf (human) that has a Ser residue at the position equivalent to Asn-581 of the amino acid sequence represented by UniProtKB:P15056, that has had the initiator methionine removed, and that has been phosphorylated on the residues at the positions equivalent to Ser-446, Thr-599, Ser-602, and Ser-729. UniProtKB:P15056, 2-766, Ser-446/Ser-602/Ser-729, MOD:00046|Asn-581, CHEBI:29999|Thr-599, MOD:00047." [PRO:DNx, Reactome:R-HSA-9648866]
organism-modification
PR:000063882
serine/threonine-protein kinase B-raf sequence variant G469Q, initiator methionine removed phosphorylated 2 (human)
hBRAF/var:G469Q/InitMet-/Phos:2
"A serine/threonine-protein kinase B-raf (human) that has a Gln residue at the position equivalent to Gly-469 of the amino acid sequence represented by UniProtKB:P15056, that has had the initiator methionine removed, and that has been phosphorylated on the residues at the positions equivalent to Ser-446, Thr-599, Ser-602, and Ser-729. UniProtKB:P15056, 2-766, Ser-446/Ser-602/Ser-729, MOD:00046|Gly-469, CHEBI:30011|Thr-599, MOD:00047." [PRO:DNx, Reactome:R-HSA-9648634]
organism-modification
PR:000063916
serine/threonine-protein kinase B-raf sequence variant N581D, initiator methionine removed phosphorylated 2 (human)
hBRAF/var:N581D/InitMet-/Phos:2
"A serine/threonine-protein kinase B-raf (human) that has an Asp residue at the position equivalent to Asn-581 of the amino acid sequence represented by UniProtKB:P15056, that has had the initiator methionine removed, and that has been phosphorylated on the residues at the positions equivalent to Ser-446, Thr-599, Ser-602, and Ser-729. UniProtKB:P15056, 2-766, Ser-446/Ser-602/Ser-729, MOD:00046|Asn-581, CHEBI:29958|Thr-599, MOD:00047." [PRO:DNx, Reactome:R-HSA-9651191]
organism-modification
PR:000064045
serine/threonine-protein kinase B-raf sequence variant L505H, initiator methionine removed phosphorylated 2 (human)
hBRAF/var:L505H/InitMet-/Phos:2
"A serine/threonine-protein kinase B-raf (human) that has a His residue at the position equivalent to Leu-505 of the amino acid sequence represented by UniProtKB:P15056, that has had the initiator methionine removed, and that has been phosphorylated on the residues at the positions equivalent to Ser-446, Thr-599, Ser-602, and Ser-729. UniProtKB:P15056, 2-766, Ser-446/Ser-602/Ser-729, MOD:00046|Leu-505, CHEBI:29979|Thr-599, MOD:00047." [PRO:DNx, Reactome:R-HSA-9648862]
organism-modification
PR:000064163
serine/threonine-protein kinase B-raf sequence variant E586K, initiator methionine removed phosphorylated 2 (human)
hBRAF/var:E586K/InitMet-/Phos:2
"A serine/threonine-protein kinase B-raf (human) that has a Lys residue at the position equivalent to Glu-586 of the amino acid sequence represented by UniProtKB:P15056, that has had the initiator methionine removed, and that has been phosphorylated on the residues at the positions equivalent to Ser-446, Thr-599, Ser-602, and Ser-729. UniProtKB:P15056, 2-766, Ser-446/Ser-602/Ser-729, MOD:00046|Glu-586, CHEBI:29967|Thr-599, MOD:00047." [PRO:DNx, Reactome:R-HSA-8936639]
organism-modification
PR:000064531
serine/threonine-protein kinase B-raf sequence variant G466A, initiator methionine removed phosphorylated 1 (human)
hBRAF/var:G466A/InitMet-/Phos:1
"A serine/threonine-protein kinase B-raf (human) that has an Ala residue at the position equivalent to Gly-466 of the amino acid sequence represented by UniProtKB:P15056, that has had the initiator methionine removed, and that has been phosphorylated on the residues at the positions equivalent to Ser-446, Thr-599, Ser-602, and Ser-729. UniProtKB:P15056, 2-766, Ser-446/Ser-602/Ser-729, MOD:00046|Gly-466, CHEBI:46217|Thr-599, MOD:00047." [PRO:DNx, Reactome:R-HSA-9648629]
