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Protein Ontology report - epidermal growth factor receptor sequence variant T790M/L858R, signal peptide removed form (human)
PR:000062613 -
http://purl.obolibrary.org/obo/PR_000062613
Ontology Information
Show OBO stanza
/
GPI
PRO ID
PR:000062613
PRO name
epidermal growth factor receptor sequence variant T790M/L858R, signal peptide removed form (human)
Synonyms
PRO-Short-label
:
EXACT:
hEGFR/var:(T790M/L858R)/SigPep-
PRO-proteoform-std
:
EXACT:
UniProtKB:P00533
, 25-1210, Thr-790,
CHEBI:16044
|Leu-858,
CHEBI:29952
NARROW:
UniProtKB:P00533-1
, 25-1210, Thr-790,
CHEBI:16044
|Leu-858,
CHEBI:29952
Reactome-displayName
:
RELATED:
EGFR L858R;T790M
Definition
"An epidermal growth factor receptor (human) that has a Met residue at the position equivalent to Thr-790 and an Arg residue at the position equivalent to Leu-858 of the amino acid sequence represented by
UniProtKB:P00533-1
and that has had the signal peptide removed. Example:
UniProtKB:P00533-1
, 25-1210, Thr-790,
CHEBI:16044
|Leu-858,
CHEBI:29952
." [PRO:DNx,
Reactome:R-HSA-1181386
]
PRO Category
organism-modification
Parent
PR:000028422
epidermal growth factor receptor, signal peptide removed form (human)
Taxon
NCBITaxon:9606
Homo sapiens
Term Hierarchy
Visualization
DAG:
OLS: