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family
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|
 PR:000050018 |
   GLI protein
 |
   fam:GLI
 |
  "A protein that is a translation product of the human GLI1, GLI2, or GLI3 genes, or 1:1 orthologs thereof." [PRO:DAN]
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gene
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|
 PR:000008026 |
   zinc finger protein GLI1
 |
   GLI1
 |
  "A GLI protein that is a translation product of the human GLI1 gene or a 1:1 ortholog thereof." [PRO:DNx]
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organism-gene
 |


|
 PR:P08151 |
   zinc finger protein GLI1 (human)
 |
   hGLI1
 |
  "A zinc finger protein GLI1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P08151]
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organism-sequence
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|
 PR:P08151-1 |
   zinc finger protein GLI1 isoform h1 (human)
 |
   hGLI1/iso:h1
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  "A zinc finger protein GLI1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P08151-1." [PRO:DNx, UniProtKB:P08151]
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organism-sequence
 |


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 PR:P08151-2 |
   zinc finger protein GLI1 isoform h2 (human)
 |
   hGLI1/iso:h2
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  "A zinc finger protein GLI1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P08151-2." [PRO:DNx, UniProtKB:P08151]
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organism-sequence
 |


|
 PR:P08151-3 |
   zinc finger protein GLI1 isoform h3 (human)
 |
   hGLI1/iso:h3
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  "A zinc finger protein GLI1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P08151-3." [PRO:DNx, UniProtKB:P08151]
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organism-modification
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|
 PR:000047544 |
   zinc finger protein GLI1 phosphorylated form (human)
 |
   hGLI1/PhosRes+
 |
  "A zinc finger protein GLI1 (human) that includes at least one phosphorylated residue. UniProtKB:P08151, MOD:00696." [PRO:DNx, Reactome:R-HSA-5635040]
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organism-modification
 |


|
 PR:000047545 |
   zinc finger protein GLI1 phosphoserine form (human)
 |
   hGLI1/PhosSer+
 |
  "A zinc finger protein GLI1 (human) that includes at least one phosphorylated serine. UniProtKB:P08151, MOD:00046." [PRO:DNx, Reactome:R-HSA-5610497]
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organism-modification
 |


|
 PR:000045655 |
   zinc finger protein GLI1 phosphorylated 1 (human)
 |
   hGLI1/Phos:1
 |
  "A zinc finger protein GLI1 (human) that has been phosphorylated on the residue at the position equivalent to Ser-84 of the amino acid sequence represented by UniProtKB:P08151-1. Example: UniProtKB:P08151-1, Ser-84, MOD:00046." [iPTMnet:P08151, PMID:22439934]
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organism-modification
 |


|
 PR:000047547 |
   zinc finger protein GLI1 phosphorylated serine and ubiquitinated form (human)
 |
   hGLI1/pSerUbiq+
 |
  "A zinc finger protein GLI1 (human) that includes at least one phosphorylated serine and at least one ubiquitinated lysine. UniProtKB:P08151, MOD:00046|MOD:01148." [PRO:DNx, Reactome:R-HSA-5610514]
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organism-modification
 |


|
 PR:000047545 |
   zinc finger protein GLI1 phosphoserine form (human)
 |
   hGLI1/PhosSer+
 |
  "A zinc finger protein GLI1 (human) that includes at least one phosphorylated serine. UniProtKB:P08151, MOD:00046." [PRO:DNx, Reactome:R-HSA-5610497]
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organism-modification
 |


|
 PR:000045655 |
   zinc finger protein GLI1 phosphorylated 1 (human)
 |
   hGLI1/Phos:1
 |
  "A zinc finger protein GLI1 (human) that has been phosphorylated on the residue at the position equivalent to Ser-84 of the amino acid sequence represented by UniProtKB:P08151-1. Example: UniProtKB:P08151-1, Ser-84, MOD:00046." [iPTMnet:P08151, PMID:22439934]
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organism-modification
 |


|
 PR:000047547 |
   zinc finger protein GLI1 phosphorylated serine and ubiquitinated form (human)
 |
   hGLI1/pSerUbiq+
 |
  "A zinc finger protein GLI1 (human) that includes at least one phosphorylated serine and at least one ubiquitinated lysine. UniProtKB:P08151, MOD:00046|MOD:01148." [PRO:DNx, Reactome:R-HSA-5610514]
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organism-modification
 |


|
 PR:000047546 |
   zinc finger protein GLI1 ubiquitinated form (human)
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   hGLI1/UbiqLys+
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  "A zinc finger protein GLI1 (human) that includes at least one ubiquitinated lysine. UniProtKB:P08151, MOD:01148." [PRO:DNx, Reactome:R-HSA-5635833]
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organism-modification
 |


|
 PR:000047547 |
   zinc finger protein GLI1 phosphorylated serine and ubiquitinated form (human)
 |
   hGLI1/pSerUbiq+
 |
  "A zinc finger protein GLI1 (human) that includes at least one phosphorylated serine and at least one ubiquitinated lysine. UniProtKB:P08151, MOD:00046|MOD:01148." [PRO:DNx, Reactome:R-HSA-5610514]
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organism-modification
 |


|
 PR:000047547 |
   zinc finger protein GLI1 phosphorylated serine and ubiquitinated form (human)
 |
   hGLI1/pSerUbiq+
 |
  "A zinc finger protein GLI1 (human) that includes at least one phosphorylated serine and at least one ubiquitinated lysine. UniProtKB:P08151, MOD:00046|MOD:01148." [PRO:DNx, Reactome:R-HSA-5610514]
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organism-modification
 |


|
 PR:000062364 |
   zinc finger protein GLI1 phosphorylated(2+) form (human)
 |
   hGLI1/PhosRes(2+)
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  "A zinc finger protein GLI1 (human) that includes at least two phosphorylated residues. UniProtKB:P08151, MOD:00696(2+)." [PRO:DNx, Reactome:R-HSA-5635057]
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organism-gene
 |


|
 PR:P47806 |
   zinc finger protein GLI1 (mouse)
 |
   mGLI1
 |
  "A zinc finger protein GLI1 that is encoded in the genome of mouse." [OMA:P47806, PRO:DNx]
 |

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gene
 |


|
 PR:000008027 |
   zinc finger protein GLI2
 |
   GLI2
 |
  "A GLI protein that is a translation product of the human GLI2 gene or a 1:1 ortholog thereof." [PRO:DNx]
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organism-gene
 |


|
 PR:P10070 |
   zinc finger protein GLI2 (human)
 |
   hGLI2
 |
  "A zinc finger protein GLI2 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P10070]
 |

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organism-sequence
 |


|
 PR:P10070-1 |
   zinc finger protein GLI2 isoform h1 (human)
 |
   hGLI2/iso:h1
 |
  "A zinc finger protein GLI2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P10070-1." [PRO:DNx, UniProtKB:P10070]
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organism-sequence
 |


|
 PR:P10070-2 |
   zinc finger protein GLI2 isoform h2 (human)
 |
   hGLI2/iso:h2
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  "A zinc finger protein GLI2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P10070-2." [PRO:DNx, UniProtKB:P10070]
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organism-sequence
 |


|
 PR:P10070-3 |
   zinc finger protein GLI2 isoform h3 (human)
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   hGLI2/iso:h3
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  "A zinc finger protein GLI2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P10070-3." [PRO:DNx, UniProtKB:P10070]
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organism-sequence
 |


|
 PR:P10070-4 |
   zinc finger protein GLI2 isoform h4 (human)
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   hGLI2/iso:h4
 |
  "A zinc finger protein GLI2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P10070-4." [PRO:DNx, UniProtKB:P10070]
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 |  |  |
organism-sequence
 |


|
 PR:P10070-5 |
   zinc finger protein GLI2 isoform h5 (human)
 |
   hGLI2/iso:h5
 |
  "A zinc finger protein GLI2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P10070-5." [PRO:DNx, UniProtKB:P10070]
 |

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organism-modification
 |


|
 PR:000060824 |
   zinc finger protein GLI2 phosphorylated 1 (human)
 |
   hGLI2/Phos:1
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  "A zinc finger protein GLI2 (human) that has been phosphorylated on the residues at the positions equivalent to Ser-808, Ser-811, Ser-824, Ser-827, Ser-836, Ser-839, Ser-867, and Ser-870 of the amino acid sequence represented by UniProtKB:P10070-5. Example: UniProtKB:P10070-5, Ser-808/Ser-811/Ser-824/Ser-827/Ser-836/Ser-839/Ser-867/Ser-870, MOD:00046." [PRO:DNx, Reactome:R-HSA-5610494]
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organism-modification
 |


|
 PR:000061717 |
   zinc finger protein GLI2 phosphorylated(2+) and ubiquitinated form (human)
 |
   hGLI2/PhosRes(2+)UbiqLys+
 |
  "A zinc finger protein GLI2 (human) that includes at least one ubiquitinated lysine and at least two phosphorylated residues. UniProtKB:P10070, MOD:00696(2+)|MOD:01148." [PRO:DNx, Reactome:R-HSA-5635059]
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organism-modification
 |


|
 PR:000062161 |
   zinc finger protein GLI2 phosphorylated(2+) form (human)
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   hGLI2/PhosRes(2+)
 |
  "A zinc finger protein GLI2 (human) that includes at least two phosphorylated residues. UniProtKB:P10070, MOD:00696(2+)." [PRO:DNx, Reactome:R-HSA-5635055]
 |

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organism-modification
 |


|
 PR:000063266 |
   zinc finger protein GLI2 phosphorylated 2 (human)
 |
   hGLI2/Phos:2
 |
  "A zinc finger protein GLI2 (human) that has been phosphorylated on the residues at the positions equivalent to Ser-808, Ser-811, Ser-820, Ser-824, Ser-827, Ser-832, Ser-836, Ser-839, Ser-863, Ser-867, and Ser-870 of the amino acid sequence represented by UniProtKB:P10070-5. Example: UniProtKB:P10070-5, Ser-808/Ser-811/Ser-820/Ser-824/Ser-827/Ser-832/Ser-836/Ser-839/Ser-863/Ser-867/Ser-870, MOD:00046." [PRO:DNx, Reactome:R-HSA-5610471]
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organism-modification
 |


|
 PR:000063303 |
   zinc finger protein GLI2 phosphorylated and ubiquitinated 1 (human)
 |
   hGLI2/PhosUbiq:1
 |
  "A zinc finger protein GLI2 (human) that has been phosphorylated on the residues at the positions equivalent to Ser-808, Ser-811, Ser-820, Ser-824, Ser-827, Ser-832, Ser-836, Ser-839, Ser-863, Ser-867, and Ser-870 of the amino acid sequence represented by UniProtKB:P10070-5 and that includes at least one ubiquitinated lysine. Example: UniProtKB:P10070-5, Ser-808/Ser-811/Ser-820/Ser-824/Ser-827/Ser-832/Ser-836/Ser-839/Ser-863/Ser-867/Ser-870, MOD:00046|MOD:01148." [PRO:DNx, Reactome:R-HSA-5610501]
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organism-modification
 |


|
 PR:000063877 |
   zinc finger protein GLI2 phosphorylated form (human)
 |
   hGLI2/PhosRes+
 |
  "A zinc finger protein GLI2 (human) that includes at least one phosphorylated residue. UniProtKB:P10070, MOD:00696." [PRO:DNx, Reactome:R-HSA-5635044, Reactome:R-HSA-5635047]
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organism-modification
 |


|
 PR:000064601 |
   zinc finger protein GLI2 phosphorylated 3 (human)
 |
   hGLI2/Phos:3
 |
  "A zinc finger protein GLI2 (human) that has been phosphorylated on the residues at the positions equivalent to Ser-808, Ser-824, Ser-836, and Ser-867 of the amino acid sequence represented by UniProtKB:P10070-5. Example: UniProtKB:P10070-5, Ser-808/Ser-824/Ser-836/Ser-867, MOD:00046." [PRO:DNx, Reactome:R-HSA-5610487]
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organism-modification
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|
 PR:000077115 |
   zinc finger protein GLI2 deaminated 1 (human)
 |
   hGLI2/Deam:1
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  "A zinc finger protein GLI2 (human) that has been deaminated on the residue at the position equivalent to Asn-261 of the amino acid sequence represented by UniProtKB:P10070-5. Example: UniProtKB:P10070-5, Asn-261, MOD:00684." [IEDB_epitope:1366242, PRO:DNx]
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organism-gene
 |


|
 PR:Q0VGT2 |
   zinc finger protein GLI2 (mouse)
 |
   mGLI2
 |
  "A zinc finger protein GLI2 that is encoded in the genome of mouse." [OMA:Q0VGT2, PRO:DNx]
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gene
 |


|
 PR:000008028 |
   transcriptional activator GLI3
 |
   GLI3
 |
  "A GLI protein that is a translation product of the human GLI3 gene or a 1:1 ortholog thereof." [PRO:DNx]
 |

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organism-gene
 |


|
 PR:P10071 |
   transcriptional activator GLI3 (human)
 |
   hGLI3
 |
  "A transcriptional activator GLI3 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P10071]
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organism-modification
 |


|
 PR:000047549 |
   transcriptional activator GLI3 phosphorylated form (human)
 |
   hGLI3/PhosRes+
 |
  "A transcriptional activator GLI3 (human) that includes at least one phosphorylated residue. UniProtKB:P10071, MOD:00696." [PRO:DNx, Reactome:R-HSA-5635048]
 |

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|  |  |  |  |  |  |  |  |  |  |
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organism-modification
 |


|
 PR:000047548 |
   transcriptional activator GLI3 phosphorylated 1 (human)
 |
   hGLI3/Phos:1
 |
  "A transcriptional activator GLI3 (human) that has been post-translationally modified to include phosphoserine at positions 849, 865, 877, 907, 980 and 1006 of the amino acid sequence represented by UniProtKB:P10071. UniProtKB:P10071, Ser-849/Ser-865/Ser-877/Ser-907/Ser-980/Ser-1006, MOD:00046." [PRO:DNx, Reactome:R-HSA-5610492]
 |

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|  |  |  |  |  |  |  |  |  |  |
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organism-modification
 |


|
 PR:000061591 |
   transcriptional activator GLI3 phosphorylated 2 (human)
 |
   hGLI3/Phos:2
 |
  "A transcriptional activator GLI3 (human) that has been phosphorylated on the residues at the positions equivalent to Ser-849, Ser-865, Ser-877, Ser-907, Ser-980, and Ser-1006 of the amino acid sequence represented by UniProtKB:P10071 and that includes at least four additional phosphorylated serines. UniProtKB:P10071, Ser-849/Ser-865/Ser-877/Ser-907/Ser-980/Ser-1006, MOD:00046|MOD:00046(4+)." [PRO:DNx, Reactome:R-HSA-5610454]
 |

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|  |  |  |  |  |  |  |  |  |  |
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organism-modification
 |


|
 PR:000064323 |
   transcriptional activator GLI3 phosphorylated 3 (human)
 |
   hGLI3/Phos:3
 |
  "A transcriptional activator GLI3 (human) that has been phosphorylated on the residues at the positions equivalent to Ser-849, Ser-865, Ser-877, Ser-907, Ser-980, and Ser-1006 of the amino acid sequence represented by UniProtKB:P10071 and that includes at least seven additional phosphorylated serines. UniProtKB:P10071, Ser-849/Ser-865/Ser-877/Ser-907/Ser-980/Ser-1006, MOD:00046|MOD:00046(7+)." [PRO:DNx, Reactome:R-HSA-5610485]
 |

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organism-modification
 |


|
 PR:000064628 |
   transcriptional activator GLI3 phosphorylated and ubiquitinated 1 (human)
 |
   hGLI3/PhosUbiq:1
 |
  "A transcriptional activator GLI3 (human) that has been phosphorylated on the residues at the positions equivalent to Ser-849, Ser-865, Ser-877, Ser-907, Ser-980 and Ser-1006, and ubiquitinated on the residues at the positions equivalent to Lys-773, Lys-779, Lys-784, and Lys-800 of the amino acid sequence represented by UniProtKB:P10071 and that includes at least seven additional phosphorylated serines. UniProtKB:P10071, Lys-773/Lys-779/Lys-784/Lys-800, MOD:01148|Ser-849/Ser-865/Ser-877/Ser-907/Ser-980/Ser-1006, MOD:00046|MOD:00046(7+)." [PRO:DNx, Reactome:R-HSA-5610506]
 |

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 |  |  |
organism-modification
 |


|
 PR:000047550 |
   transcriptional activator GLI3 phosphorylated(2+) and ubiquitinated form (human)
 |
   hGLI3/Phos(2+)Ubiq+
 |
  "A transcriptional activator GLI3 (human) that includes at least two phosphorylated residues and at least one ubiquitinated lysine. UniProtKB:P10071, MOD:00696(2+)|MOD:01148." [PRO:DNx, Reactome:R-HSA-5635060]
 |

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 |  |  |
organism-modification
 |


|
 PR:000063350 |
   transcriptional activator GLI3 phosphorylated(2+) form (human)
 |
   hGLI3/PhosRes(2+)
 |
  "A transcriptional activator GLI3 (human) that includes at least two phosphorylated residues. UniProtKB:P10071, MOD:00696(2+)." [PRO:DNx, Reactome:R-HSA-5635052]
 |

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organism-gene
 |


|
 PR:Q61602 |
   transcriptional activator GLI3 (mouse)
 |
   mGLI3
 |
  "A transcriptional activator GLI3 that is encoded in the genome of mouse." [OMA:Q61602, PRO:DNx]
 |

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 |  |  |
organism-modification
 |


|
 PR:000037267 |
   transcriptional activator GLI3 precursor (mouse)
 |
   mGLI3/precursor
 |
  "A transcriptional activator GLI3 (mouse) that has not been subjected to any proteolytic cleavage. UniProtKB:Q61602, 1-1583." [PMID:10693759, PRO:KRC]
 |

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organism-modification
 |


|
 PR:000037268 |
   transcriptional repressor GLI3R (mouse)
 |
   mGLI3/Clv:GLI3R
 |
  "A transcriptional activator GLI3 precursor (mouse) that has been processed by proteolytic cleavage, removing the C-terminal region. UniProtKB:Q61602, 1-?." [PMID:10693759, PRO:KRC]
 |

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modification
 |


|
 PR:000037271 |
   transcriptional activator GLI3 proteolytic cleavage product
 |
   GLI3/ClvPrd
 |
  "A transcriptional activator GLI3 that has been processed by proteolytic cleavage." [PRO:CNA, PRO:DAN]
 |

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 |  |  |
organism-modification
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 PR:000037268 |
   transcriptional repressor GLI3R (mouse)
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   mGLI3/Clv:GLI3R
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  "A transcriptional activator GLI3 precursor (mouse) that has been processed by proteolytic cleavage, removing the C-terminal region. UniProtKB:Q61602, 1-?." [PMID:10693759, PRO:KRC]
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