back to PRO homepage
  Home |   Linked Open Data |   Browse |  
Search

|   Statistics |   Download
 RACE-PRO
 PRO tracker
 Community
 PRO Consortium
 Publications
 Documentation

Protein Ontology report - protein kinase C, iota-like
PR:000045383 - http://purl.obolibrary.org/obo/PR_000045383
 
  Protein Forms      
Ontology Information Show OBO stanza
  PRO ID
PR:000045383   
  PRO nameprotein kinase C, iota-like 
  Synonyms
PRO-Short-label: EXACT:fam:aPKC
Other: RELATED:atypical PKC
  Definition"A protein that is a member of the phorbol ester (and diacylglycerol) receptor/protein kinase class. The canonical protein sequence has a core domain architecture consisting of a copy of the PB1 domain (Pfam:PF:00564), a Phorbol esters/diacylglycerol binding domain (C1 domain) (Pfam:PF00130), a Protein kinase domain (Pfam:PF00069) and a Protein kinase C terminal domain (Pfam:PF00433)." [PMID:8226978
  PRO Categoryfamily 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Family1                                                  Organism-Family 0                                        
         Gene2                                                  Organism-Gene 8                                        
         Sequence1                                                  Organism-Sequence 12                                        
         Modification0                                                  Organism-Modification 5                                        
  Term Hierarchy
  Visualization
DAG: OLS:
Back to top
Related Cross References

  Db identifiers
PIRSF:PIRSF000554
Back to top
Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
family



PR:000045383

protein kinase C, iota-like

fam:aPKC


"A protein that is a member of the phorbol ester (and diacylglycerol) receptor/protein kinase class. The canonical protein sequence has a core domain architecture consisting of a copy of the PB1 domain (Pfam:PF:00564), a Phorbol esters/diacylglycerol binding domain (C1 domain) (Pfam:PF00130), a Protein kinase domain (Pfam:PF00069) and a Protein kinase C terminal domain (Pfam:PF00433)." [PMID:8226978]


gene



PR:000013233

protein kinase C iota type

PRKCI


"A protein kinase C, iota-like that is a translation product of the human PRKCI gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:A1Z9X0

atypical protein kinase C (fruit fly)

fly-PRKCI


"A protein kinase C iota type that is encoded in the genome of fruit fly." [OMA:A1Z9X0, PRO:DNx]


organism-sequence



PR:A1Z9X0-1

atypical protein kinase C isoform A (fruit fly)

fly-PRKCI/iso:A


"An atypical protein kinase C (fruit fly) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:A1Z9X0-1." [PRO:DNx, UniProtKB:A1Z9X0]


organism-sequence



PR:A1Z9X0-2

atypical protein kinase C isoform B (fruit fly)

fly-PRKCI/iso:B


"An atypical protein kinase C (fruit fly) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:A1Z9X0-2." [PRO:DNx, UniProtKB:A1Z9X0]


organism-sequence



PR:A1Z9X0-3

atypical protein kinase C isoform D (fruit fly)

fly-PRKCI/iso:D


"An atypical protein kinase C (fruit fly) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:A1Z9X0-3." [PRO:DNx, UniProtKB:A1Z9X0]


organism-sequence



PR:A1Z9X0-4

atypical protein kinase C isoform E (fruit fly)

fly-PRKCI/iso:E


"An atypical protein kinase C (fruit fly) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:A1Z9X0-4." [PRO:DNx, UniProtKB:A1Z9X0]


organism-sequence



PR:A1Z9X0-5

atypical protein kinase C isoform F (fruit fly)

fly-PRKCI/iso:F


"An atypical protein kinase C (fruit fly) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:A1Z9X0-5." [PRO:DNx, UniProtKB:A1Z9X0]


organism-gene



PR:F1M7Y5

protein kinase C iota type (rat)

rPRKCI


"A protein kinase C iota type that is encoded in the genome of rat." [OMA:F1M7Y5, PRO:DNx]


organism-gene



PR:P41743

protein kinase C iota type (human)

hPRKCI


"A protein kinase C iota type that is encoded in the genome of human." [PRO:DNx, UniProtKB:P41743]


organism-modification



PR:000048919

protein kinase C iota type, initiator methionine removed form (human)

hPRKCI/InitMet-


"A protein kinase C iota type (human) that has had the initiator methionine removed. UniProtKB:P41743, 2-596." [PRO:DNx, Reactome:R-HSA-420005, Reactome:R-HSA-58206]


organism-gene



PR:Q62074

protein kinase C iota type (mouse)

mPRKCI


"A protein kinase C iota type that is encoded in the genome of mouse." [OMA:Q62074, PRO:DNx]


organism-gene



PR:Q90XF2

protein kinase C iota type (zebrafish)

z-PRKCI


"A protein kinase C iota type that is encoded in the genome of zebrafish." [OMA:Q90XF2, PRO:DNx]


gene



PR:000013235

protein kinase C zeta type

PRKCZ


"A protein kinase C, iota-like that is a translation product of the human PRKCZ gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:P09217

protein kinase C zeta type (rat)

rPRKCZ


"A protein kinase C zeta type that is encoded in the genome of rat." [OMA:P09217, PRO:DNx]


organism-sequence



PR:P09217-1

protein kinase C zeta type isoform 1 (rat)

rPRKCZ/iso:1


"A protein kinase C zeta type isoform 1 that is encoded in the genome of rat." [PRO:DNx]


organism-sequence



PR:P09217-2

protein kinase C zeta type isoform r2 (rat)

rPRKCZ/iso:r2


"A protein kinase C zeta type (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P09217-2." [PRO:DNx, UniProtKB:P09217]


organism-gene



PR:Q02956

protein kinase C zeta type (mouse)

mPRKCZ


"A protein kinase C zeta type that is encoded in the genome of mouse." [OMA:Q02956, PRO:DNx]


organism-sequence



PR:Q02956-1

protein kinase C zeta type isoform 1 (mouse)

mPRKCZ/iso:1


"A protein kinase C zeta type isoform 1 that is encoded in the genome of mouse." [PRO:DNx]


organism-sequence



PR:Q02956-2

protein kinase C zeta type isoform m2 (mouse)

mPRKCZ/iso:m2


"A protein kinase C zeta type (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q02956-2." [PRO:DNx, UniProtKB:Q02956]


organism-modification



PR:000045530

protein kinase C zeta type phosphorylated 1 (mouse)

mPRKCZ/Phos:1


"A protein kinase C zeta type (mouse) that has been phosphorylated on a Thr residue equivalent to Thr-410 of the amino acid sequence represented by UniProtKB:Q02956. UniProtKB:Q02956, Thr-410, MOD:00047." [PMID:22333836, PRO:KRC]


organism-gene



PR:Q05513

protein kinase C zeta type (human)

hPRKCZ


"A protein kinase C zeta type that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q05513]


organism-sequence



PR:Q05513-1

protein kinase C zeta type isoform 1 (human)

hPRKCZ/iso:1


"A protein kinase C zeta type isoform 1 that is encoded in the genome of human." [PRO:DNx]


organism-sequence



PR:Q05513-2

protein kinase C zeta type isoform h2 (human)

hPRKCZ/iso:h2


"A protein kinase C zeta type (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q05513-2." [PRO:DNx, UniProtKB:Q05513]


organism-sequence



PR:Q05513-3

protein kinase C zeta type isoform h3 (human)

hPRKCZ/iso:h3


"A protein kinase C zeta type (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q05513-3." [PRO:DNx, UniProtKB:Q05513]


organism-modification



PR:000045879

protein kinase C zeta type phosphorylated 1 (human)

hPRKCZ/Phos:1


"A protein kinase C zeta type (human) that has been phosphorylated on the residue at the position equivalent to Thr-410 of the amino acid sequence represented by UniProtKB:Q05513-1. Example: UniProtKB:Q05513-1, Thr-410, MOD:00047." [iPTMnet:Q05513, PMID:11222751, PMID:12887331, PMID:15314172, PMID:17335005, PMID:9768361]


organism-modification



PR:000048924

protein kinase C zeta type phosphorylated 2 (human)

hPRKCZ/Phos:2


"A protein kinase C zeta type (human) that has been post-translationally modified to include phosphothreonine at positions 410 and 560 of the amino acid sequence represented by UniProtKB:Q05513. UniProtKB:Q05513, Thr-410/Thr-560, MOD:00047." [PRO:DNx, Reactome:R-HSA-5218698]


organism-modification



PR:000061210

protein kinase C zeta type phosphorylated 3 (human)

hPRKCZ/Phos:3


"A protein kinase C zeta type (human) that has been phosphorylated on the residue at the position equivalent to Thr-410 of the amino acid sequence represented by UniProtKB:Q05513-1 and that includes at least one phosphorylated serine. Example: UniProtKB:Q05513-1, Thr-410, MOD:00047|MOD:00046." [PRO:DNx, Reactome:R-HSA-9632824]


sequence



PR:000040284

protein kinase C zeta type isoform 1

PRKCZ/iso:1


"A protein kinase C zeta type that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q05513-1 or a 1:1 ortholog thereof." [PRO:DNx]


organism-sequence



PR:P09217-1

protein kinase C zeta type isoform 1 (rat)

rPRKCZ/iso:1


"A protein kinase C zeta type isoform 1 that is encoded in the genome of rat." [PRO:DNx]


organism-sequence



PR:Q02956-1

protein kinase C zeta type isoform 1 (mouse)

mPRKCZ/iso:1


"A protein kinase C zeta type isoform 1 that is encoded in the genome of mouse." [PRO:DNx]


organism-sequence



PR:Q05513-1

protein kinase C zeta type isoform 1 (human)

hPRKCZ/iso:1


"A protein kinase C zeta type isoform 1 that is encoded in the genome of human." [PRO:DNx]