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Protein Ontology report - cyclic nucleotide-gated channel alpha-1 isoform 1 phosphorylated 2
PR:000045378 - http://purl.obolibrary.org/obo/PR_000045378
 
  Protein Forms      
Ontology Information Show OBO stanza
  PRO ID
PR:000045378   
  PRO namecyclic nucleotide-gated channel alpha-1 isoform 1 phosphorylated 2 
  Synonyms
PRO-Short-label: EXACT:CNGA1/iso:1/Phos:2
  Definition"A cyclic nucleotide-gated channel alpha-1 isoform 1 phosphorylated form in which the phosphorylation occurs at the Tyr residue within the VYSPGD motif located at the N terminus of the cyclic-nucleotide binding domain (CNDB) and the residue at the position equivalent to Tyr-503 of the amino acid sequence represented by UniProtKB:Q00194-1. This phosphorylation prevents Ca2+/CaM inhibition of the CNG channel, but at the same time has a similar effect, that is decreases the apparent affinity for cGMP. Example: UniProtKB:Q00194-1, Tyr-498/Tyr-503, MOD:00048." [PMID:23032687, PRO:CNA, PRO:DAN] 
  PRO Categorymodification 
  ParentPR:000000932 cyclic nucleotide-gated channel alpha-1 isoform 1 phosphorylated form
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Modification1                                                  Organism-Modification 1                                        
  Term Hierarchy
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Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

Comp. In Complex?
modification


PR:000045378
cyclic nucleotide-gated channel alpha-1 isoform 1 phosphorylated 2
CNGA1/iso:1/Phos:2
"A cyclic nucleotide-gated channel alpha-1 isoform 1 phosphorylated form in which the phosphorylation occurs at the Tyr residue within the VYSPGD motif located at the N terminus of the cyclic-nucleotide binding domain (CNDB) and the residue at the position equivalent to Tyr-503 of the amino acid sequence represented by UniProtKB:Q00194-1. This phosphorylation prevents Ca2+/CaM inhibition of the CNG channel, but at the same time has a similar effect, that is decreases the apparent affinity for cGMP. Example: UniProtKB:Q00194-1, Tyr-498/Tyr-503, MOD:00048." [PMID:23032687, PRO:CNA, PRO:DAN]

organism-modification


PR:000045379
cyclic nucleotide-gated channel alpha-1 isoform 1 phosphorylated 2 (cow)
cow-CNGA1/iso:1/Phos:2
"A cyclic nucleotide-gated channel alpha-1 isoform 1 phosphorylated 2 in cow. UniProtKB:Q00194-1, Tyr-498/Tyr-503, MOD:00048." [PMID:15381690, PRO:CNA]