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Protein Ontology report - insulin family protein
PR:000045358 - http://purl.obolibrary.org/obo/PR_000045358
 
  Protein Forms      
Ontology Information Show OBO stanza
  PRO ID
PR:000045358   
  PRO nameinsulin family protein 
  Synonyms
PRO-Short-label: EXACT:fam:INS
  Definition"A protein that is a translation product of a gene that encodes a standalone Insulin (Pfam:PF00049) domain preceded by a signal peptide." [PRO:DAN] 
  PRO Categoryfamily 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Family1                                                  Organism-Family 0                                        
         Gene3                                                  Organism-Gene 5                                        
         Sequence0                                                  Organism-Sequence 0                                        
         Modification6                                                  Organism-Modification 13                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
family



PR:000045358

insulin family protein

fam:INS


"A protein that is a translation product of a gene that encodes a standalone Insulin (Pfam:PF00049) domain preceded by a signal peptide." [PRO:DAN]


gene



PR:000009054

preproinsulin

INS


"An insulin family protein that is a translation product of the human INS gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:O73727

insulin (zebrafish)

z-INS


"A preproinsulin that is encoded in the genome of zebrafish." [PRO:DNx]


organism-gene



PR:P01308

preproinsulin (human)

hINS


"A preproinsulin that is encoded in the genome of human." [PRO:DAN, UniProtKB:P01308]


organism-modification



PR:000048036

proinsulin (human)

hINS/SigPep-


"A proinsulin in human. UniProtKB:P01308, 25-110." [PRO:DAN, UniProtKB:P01308]


organism-modification



PR:000050340

insulin hormone (human)

insulin (human)


"An insulin hormone in human." [PRO:DAN]


organism-modification



PR:000064810

proinsulin isoform 1 (human)

hINS/iso:1/SigPep-


"A preproinsulin (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P01308-1 and that has had the signal peptide removed. UniProtKB:P01308-1, 25-110." [PRO:DAN, UniProtKB:P01308]


organism-modification



PR:000084885

insulin citrullinated 1 (human)

hINS/Cit:1


"A preproinsulin (human) that has been citrullinated on the residue at the position equivalent to Arg-46 of the amino acid sequence represented by UniProtKB:P01308-1. Example: UniProtKB:P01308-1, Arg-46, MOD:00219." [IEDB_epitope:1619583, PRO:DNx]


organism-gene



PR:P67970

preproinsulin (chicken)

chick-INS


"A preproinsulin that is encoded in the genome of chicken." [OMA:P67970, PRO:DNx]


modification



PR:000020310

proinsulin

INS/SigPep-


"A preproinsulin that has had the signal peptide removed. Proinsulin consists of the insulin B and A chains linked by the C-peptide. Example: UniProtKB:P01308, 25-110." [PRO:DAN]


modification



PR:000050339

insulin hormone

insulin


"A proinsulin that has had the propeptide (C-peptide) excised, leaving the A chain (example: UniProtKB:P01308, 90-110) and B chain (example: UniProtKB:P01308, 25-54) connected by crosslinks." [PRO:DAN]


organism-modification



PR:000050340

insulin hormone (human)

insulin (human)


"An insulin hormone in human." [PRO:DAN]


organism-modification



PR:000048036

proinsulin (human)

hINS/SigPep-


"A proinsulin in human. UniProtKB:P01308, 25-110." [PRO:DAN, UniProtKB:P01308]


organism-modification



PR:000050340

insulin hormone (human)

insulin (human)


"An insulin hormone in human." [PRO:DAN]


gene



PR:000009189

insulin-1

Ins1


"An insulin family protein that is a translation product of the mouse Ins1 gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:P01325

insulin-1 (mouse)

mIns1


"An insulin-1 that is encoded in the genome of mouse." [PRO:DNx, UniProtKB:P01325]


organism-modification



PR:000065712

insulin-1 deaminated 1 (mouse)

mIns1/Deam:1


"An insulin-1 (mouse) that has been deaminated on the residue at the position equivalent to Gln-65 of the amino acid sequence represented by UniProtKB:P01325. UniProtKB:P01325, Gln-65, MOD:00685." [IEDB_epitope:1396064, PRO:DNx]


organism-modification



PR:000079263

insulin-1 deaminated 2 (mouse)

mIns1/Deam:2


"An insulin-1 (mouse) that has been deaminated on the residue at the position equivalent to Gln-85 of the amino acid sequence represented by UniProtKB:P01325. UniProtKB:P01325, Gln-85, MOD:00685." [IEDB_epitope:1389685, IEDB_epitope:1396465, PRO:DNx]


organism-modification



PR:000085074

insulin-1 deaminated 3 (mouse)

mIns1/Deam:3


"An insulin-1 (mouse) that has been deaminated on the residue at the position equivalent to Gln-62 of the amino acid sequence represented by UniProtKB:P01325. UniProtKB:P01325, Gln-62, MOD:00685." [IEDB_epitope:1386839, IEDB_epitope:1386845, IEDB_epitope:1396061, PRO:DNx]


modification



PR:000020359

insulin-1, signal peptide removed form

Ins1/SigPep-


"An insulin-1 that has had the signal peptide removed." [PRO:DNx]


modification



PR:000020360

insulin-1 proteolytic cleavage product

Ins1/ClvPrd


"An insulin-1 that has been processed by proteolytic cleavage." [PRO:DNx]


gene



PR:000009190

insulin-2

Ins2


"An insulin family protein that is a translation product of the mouse Ins2 gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:P01326

insulin-2 (mouse)

mIns2


"An insulin-2 that is encoded in the genome of mouse." [PRO:DNx, UniProtKB:P01326]


organism-modification



PR:000065630

insulin-2 glutathionylated 1 (mouse)

mIns2/SGlt:1


"An insulin-2 (mouse) that has been glutathionylated on the residue at the position equivalent to Cys-109 of the amino acid sequence represented by UniProtKB:P01326. UniProtKB:P01326, Cys-109, MOD:00234." [IEDB_epitope:1406339, PRO:DNx]


organism-modification



PR:000065756

insulin-2 cysteinylated 1 (mouse)

mIns2/Cyst:1


"An insulin-2 (mouse) that has been cysteinylated on the residue at the position equivalent to Cys-109 of the amino acid sequence represented by UniProtKB:P01326. UniProtKB:P01326, Cys-109, MOD:00765." [IEDB_epitope:1406337, PRO:DNx]


organism-modification



PR:000070486

insulin-2 methylated 1 (mouse)

mIns2/Me:1


"An insulin-2 (mouse) that has been methylated on the residue at the position equivalent to Asn-110 of the amino acid sequence represented by UniProtKB:P01326. UniProtKB:P01326, Asn-110, MOD:00673." [IEDB_epitope:1406340, PRO:DNx]


organism-modification



PR:000070644

insulin-2 deaminated 1 (mouse)

mIns2/Deam:1


"An insulin-2 (mouse) that has been deaminated on the residue at the position equivalent to Gln-78 of the amino acid sequence represented by UniProtKB:P01326. UniProtKB:P01326, Gln-78, MOD:00685." [IEDB_epitope:1395063, PRO:DNx]


organism-modification



PR:000079736

insulin-2 deaminated 2 (mouse)

mIns2/Deam:2


"An insulin-2 (mouse) that has been deaminated on the residue at the position equivalent to Gln-62 of the amino acid sequence represented by UniProtKB:P01326. UniProtKB:P01326, Gln-62, MOD:00685." [IEDB_epitope:1396020, IEDB_epitope:1396022, IEDB_epitope:1396028, IEDB_epitope:1396031, PRO:DNx]


organism-modification



PR:000082940

insulin-2 deaminated 3 (mouse)

mIns2/Deam:3


"An insulin-2 (mouse) that has been deaminated on the residue at the position equivalent to Gln-65 of the amino acid sequence represented by UniProtKB:P01326. UniProtKB:P01326, Gln-65, MOD:00685." [IEDB_epitope:1396024, IEDB_epitope:1396026, IEDB_epitope:1396029, PRO:DNx]


modification



PR:000020362

insulin-2, signal peptide removed form

Ins2/SigPep-


"An insulin-2 that has had the signal peptide removed." [PRO:DNx]


modification



PR:000020363

insulin-2 proteolytic cleavage product

Ins2/ClvPrd


"An insulin-2 that has been processed by proteolytic cleavage." [PRO:DNx]