back to PRO homepage
  Home |   Linked Open Data |   Browse |  
Search

 |   Statistics |   Download
 RACE-PRO
 PRO tracker
 Community
 PRO Consortium
 Publications
 Documentation

Protein Ontology report - pH-gated ion channel protein
PR:000044662 - http://purl.obolibrary.org/obo/PR_000044662
 
  Protein Forms      
Ontology Information Show OBO stanza
  PRO ID
PR:000044662   
  PRO namepH-gated ion channel protein 
  Synonyms
PRO-Short-label: EXACT:fam:ASIC_chan
Other: EXACT:acid-sensing ion channel protein | ASIC protein | proton-gated ion channel protein
  Definition"A ligand-gated ion channel protein that has pH-gated monoatomic ion channel activity. A pH-gated ion channel opens when an extracellular proton has been bound by the channel complex, and enables the transmembrane transfer of a sodium ion." [GO:0160128, PRO:DAN, PRO:XQ] 
  CommentNote: Acid-sensing ion channels operate as homo- or heterotrimers. [PRO:DAN, IUPHARfam:118]. 
  PRO Categoryfamily 
  ParentPR:000044671 ligand-gated ion channel protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Family1                                                  Organism-Family 0                                        
         Gene3                                                  Organism-Gene 12                                        
         Sequence3                                                  Organism-Sequence 20                                        
         Modification0                                                  Organism-Modification 0                                        
  Term Hierarchy
  Visualization
DAG: OLS:
Back to top
Related Cross References

  Db identifiers
IUPHARfam:118
Back to top
Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

Comp. In Complex?
family


PR:000044662
pH-gated ion channel protein
fam:ASIC_chan
"A ligand-gated ion channel protein that has pH-gated monoatomic ion channel activity. A pH-gated ion channel opens when an extracellular proton has been bound by the channel complex, and enables the transmembrane transfer of a sodium ion." [GO:0160128, PRO:DAN, PRO:XQ]

gene


PR:000003614
acid-sensing ion channel 2
ASIC2
"A pH-gated ion channel protein that is a translation product of the human ASIC2 gene or a 1:1 ortholog thereof." [PRO:DNx]

organism-gene


PR:Q16515
acid-sensing ion channel 2 (human)
hASIC2
"An acid-sensing ion channel 2 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q16515]

organism-sequence


PR:Q16515-1
acid-sensing ion channel 2 isoform 1 (human)
hASIC2/iso:1
"An acid-sensing ion channel 2 isoform 1 that is encoded in the genome of human." [PRO:DNx]

organism-sequence


PR:Q16515-2
acid-sensing ion channel 2 isoform 2 (human)
hASIC2/iso:2
"An acid-sensing ion channel 2 isoform 2 that is encoded in the genome of human." [PRO:DNx]

organism-gene


PR:Q62962
acid-sensing ion channel 2 (rat)
rASIC2
"An acid-sensing ion channel 2 that is encoded in the genome of rat." [OMA:Q62962, PRO:DNx]

organism-sequence


PR:Q62962-1
acid-sensing ion channel 2 isoform 1 (rat)
rASIC2/iso:1
"An acid-sensing ion channel 2 isoform 1 that is encoded in the genome of rat." [PRO:DNx]

organism-sequence


PR:Q62962-2
acid-sensing ion channel 2 isoform 2 (rat)
rASIC2/iso:2
"An acid-sensing ion channel 2 isoform 2 that is encoded in the genome of rat." [PRO:DNx]

organism-gene


PR:Q708S5
acid-sensing ion channel 2 (zebrafish)
z-ASIC2
"An acid-sensing ion channel 2 that is encoded in the genome of zebrafish." [OMA:Q708S5, PRO:DNx]

organism-gene


PR:Q925H0
acid-sensing ion channel 2 (mouse)
mASIC2
"An acid-sensing ion channel 2 that is encoded in the genome of mouse." [OMA:Q925H0, PRO:DNx]

organism-sequence


PR:Q925H0-1
acid-sensing ion channel 2 isoform 1 (mouse)
mASIC2/iso:1
"An acid-sensing ion channel 2 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]

organism-sequence


PR:Q925H0-2
acid-sensing ion channel 2 isoform 2 (mouse)
mASIC2/iso:2
"An acid-sensing ion channel 2 isoform 2 that is encoded in the genome of mouse." [PRO:DNx]

sequence


PR:000040698
acid-sensing ion channel 2 isoform 1
ASIC2/iso:1
"An acid-sensing ion channel 2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q16515-1 or a 1:1 ortholog thereof." [PRO:DNx]

organism-sequence


PR:Q16515-1
acid-sensing ion channel 2 isoform 1 (human)
hASIC2/iso:1
"An acid-sensing ion channel 2 isoform 1 that is encoded in the genome of human." [PRO:DNx]

organism-sequence


PR:Q62962-1
acid-sensing ion channel 2 isoform 1 (rat)
rASIC2/iso:1
"An acid-sensing ion channel 2 isoform 1 that is encoded in the genome of rat." [PRO:DNx]

organism-sequence


PR:Q925H0-1
acid-sensing ion channel 2 isoform 1 (mouse)
mASIC2/iso:1
"An acid-sensing ion channel 2 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]

sequence


PR:000040699
acid-sensing ion channel 2 isoform 2
ASIC2/iso:2
"An acid-sensing ion channel 2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q16515-2 or a 1:1 ortholog thereof." [PRO:DNx]

organism-sequence


PR:Q16515-2
acid-sensing ion channel 2 isoform 2 (human)
hASIC2/iso:2
"An acid-sensing ion channel 2 isoform 2 that is encoded in the genome of human." [PRO:DNx]

organism-sequence


PR:Q62962-2
acid-sensing ion channel 2 isoform 2 (rat)
rASIC2/iso:2
"An acid-sensing ion channel 2 isoform 2 that is encoded in the genome of rat." [PRO:DNx]

organism-sequence


PR:Q925H0-2
acid-sensing ion channel 2 isoform 2 (mouse)
mASIC2/iso:2
"An acid-sensing ion channel 2 isoform 2 that is encoded in the genome of mouse." [PRO:DNx]

gene


PR:000003615
acid-sensing ion channel 1
ASIC1
"A pH-gated ion channel protein that is a translation product of the human ASIC1 gene or a 1:1 ortholog thereof." [PRO:DNx]

organism-gene


PR:P55926
acid-sensing ion channel 1 (rat)
rASIC1
"An acid-sensing ion channel 1 that is encoded in the genome of rat." [OMA:P55926, PRO:DNx]

organism-sequence


PR:P55926-1
acid-sensing ion channel 1 isoform 1 (rat)
rASIC1/iso:1
"An acid-sensing ion channel 1 isoform 1 that is encoded in the genome of rat." [PRO:DNx]

organism-sequence


PR:P55926-2
acid-sensing ion channel 1 isoform rASIC-beta2 (rat)
rASIC1/iso:rASIC-beta2
"An acid-sensing ion channel 1 (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P55926-2." [PRO:DNx, UniProtKB:P55926]

organism-sequence


PR:P55926-3
acid-sensing ion channel 1 isoform rASIC1b (rat)
rASIC1/iso:rASIC1b
"An acid-sensing ion channel 1 (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P55926-3." [PRO:DNx, UniProtKB:P55926]

organism-gene


PR:P78348
acid-sensing ion channel 1 (human)
hASIC1
"An acid-sensing ion channel 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P78348]

organism-sequence


PR:P78348-1
acid-sensing ion channel 1 isoform h1 (human)
hASIC1/iso:h1
"An acid-sensing ion channel 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P78348-1." [PRO:DNx, UniProtKB:P78348]

organism-sequence


PR:P78348-2
acid-sensing ion channel 1 isoform hAsic1a (human)
hASIC1/iso:hAsic1a
"An acid-sensing ion channel 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P78348-2." [PRO:DNx, UniProtKB:P78348]

organism-sequence


PR:P78348-3
acid-sensing ion channel 1 isoform hAsic1b (human)
hASIC1/iso:hAsic1b
"An acid-sensing ion channel 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P78348-3." [PRO:DNx, UniProtKB:P78348]

organism-gene


PR:Q1XA76
acid-sensing ion channel 1 (chicken)
chick-ASIC1
"An acid-sensing ion channel 1 that is encoded in the genome of chicken." [OMA:Q1XA76, PRO:DNx]

organism-gene


PR:Q6NXK8
acid-sensing ion channel 1 (mouse)
mASIC1
"An acid-sensing ion channel 1 that is encoded in the genome of mouse." [OMA:Q6NXK8, PRO:DNx]

organism-sequence


PR:Q6NXK8-1
acid-sensing ion channel 1 isoform 1 (mouse)
mASIC1/iso:1
"An acid-sensing ion channel 1 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]

organism-sequence


PR:Q6NXK8-2
acid-sensing ion channel 1 isoform mAsic1b (mouse)
mASIC1/iso:mAsic1b
"An acid-sensing ion channel 1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6NXK8-2." [PRO:DNx, UniProtKB:Q6NXK8]

organism-gene


PR:Q708S7
acid-sensing ion channel 1A (zebrafish)
z-ASIC1
"An acid-sensing ion channel 1 that is encoded in the genome of zebrafish." [OMA:Q708S7, PRO:DAN]

sequence


PR:000041181
acid-sensing ion channel 1 isoform 1
ASIC1/iso:1
"An acid-sensing ion channel 1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6NXK8-1 or a 1:1 ortholog thereof." [PRO:DNx]

organism-sequence


PR:P55926-1
acid-sensing ion channel 1 isoform 1 (rat)
rASIC1/iso:1
"An acid-sensing ion channel 1 isoform 1 that is encoded in the genome of rat." [PRO:DNx]

organism-sequence


PR:Q6NXK8-1
acid-sensing ion channel 1 isoform 1 (mouse)
mASIC1/iso:1
"An acid-sensing ion channel 1 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]

gene


PR:000003616
acid-sensing ion channel 3
ASIC3
"A pH-gated ion channel protein that is a translation product of the human ASIC3 gene or a 1:1 ortholog thereof." [PRO:DNx]

organism-gene


PR:O35240
acid-sensing ion channel 3 (rat)
rASIC3
"An acid-sensing ion channel 3 that is encoded in the genome of rat." [OMA:O35240, PRO:DNx]

organism-gene


PR:Q6X1Y6
acid-sensing ion channel 3 (mouse)
mASIC3
"An acid-sensing ion channel 3 that is encoded in the genome of mouse." [OMA:Q6X1Y6, PRO:DNx]

organism-sequence


PR:Q6X1Y6-1
acid-sensing ion channel 3 isoform m1 (mouse)
mASIC3/iso:m1
"An acid-sensing ion channel 3 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6X1Y6-1." [PRO:DNx, UniProtKB:Q6X1Y6]

organism-sequence


PR:Q6X1Y6-2
acid-sensing ion channel 3 isoform m2 (mouse)
mASIC3/iso:m2
"An acid-sensing ion channel 3 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6X1Y6-2." [PRO:DNx, UniProtKB:Q6X1Y6]

organism-gene


PR:Q9UHC3
acid-sensing ion channel 3 (human)
hASIC3
"An acid-sensing ion channel 3 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q9UHC3]

organism-sequence


PR:Q9UHC3-1
acid-sensing ion channel 3 isoform h1 (human)
hASIC3/iso:h1
"An acid-sensing ion channel 3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9UHC3-1." [PRO:DNx, UniProtKB:Q9UHC3]

organism-sequence


PR:Q9UHC3-2
acid-sensing ion channel 3 isoform h2 (human)
hASIC3/iso:h2
"An acid-sensing ion channel 3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9UHC3-2." [PRO:DNx, UniProtKB:Q9UHC3]

organism-sequence


PR:Q9UHC3-3
acid-sensing ion channel 3 isoform h3 (human)
hASIC3/iso:h3
"An acid-sensing ion channel 3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9UHC3-3." [PRO:DNx, UniProtKB:Q9UHC3]

organism-sequence


PR:Q9UHC3-4
acid-sensing ion channel 3 isoform h4 (human)
hASIC3/iso:h4
"An acid-sensing ion channel 3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9UHC3-4." [PRO:DNx, UniProtKB:Q9UHC3]