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Protein Ontology report - pH-gated ion channel protein
PR:000044662 - http://purl.obolibrary.org/obo/PR_000044662
 
  Protein Forms      
Ontology Information Show OBO stanza
  PRO ID
PR:000044662   
  PRO namepH-gated ion channel protein 
  Synonyms
PRO-Short-label: EXACT:fam:ASIC_chan
Other: EXACT:acid-sensing ion channel protein | ASIC protein | proton-gated ion channel protein
  Definition"A ligand-gated ion channel protein that has pH-gated monoatomic ion channel activity. A pH-gated ion channel opens when an extracellular proton has been bound by the channel complex, and enables the transmembrane transfer of a sodium ion." [GO:0160128, PRO:DAN, PRO:XQ] 
  CommentNote: Acid-sensing ion channels operate as homo- or heterotrimers. [PRO:DAN, IUPHARfam:118]. 
  PRO Categoryfamily 
  ParentPR:000044671 ligand-gated ion channel protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Family1                                                  Organism-Family 0                                        
         Gene3                                                  Organism-Gene 12                                        
         Sequence3                                                  Organism-Sequence 20                                        
         Modification0                                                  Organism-Modification 0                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
IUPHARfam:118
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

Comp. In Complex?
family


PR:000044662 pH-gated ion channel protein
fam:ASIC_chan

gene


PR:000003614 acid-sensing ion channel 2
ASIC2

organism-gene


PR:Q16515 acid-sensing ion channel 2 (human)
hASIC2

organism-sequence


PR:Q16515-1 acid-sensing ion channel 2 isoform 1 (human)
hASIC2/iso:1

organism-sequence


PR:Q16515-2 acid-sensing ion channel 2 isoform 2 (human)
hASIC2/iso:2

organism-gene


PR:Q62962 acid-sensing ion channel 2 (rat)
rASIC2

organism-sequence


PR:Q62962-1 acid-sensing ion channel 2 isoform 1 (rat)
rASIC2/iso:1

organism-sequence


PR:Q62962-2 acid-sensing ion channel 2 isoform 2 (rat)
rASIC2/iso:2

organism-gene


PR:Q708S5 acid-sensing ion channel 2 (zebrafish)
z-ASIC2

organism-gene


PR:Q925H0 acid-sensing ion channel 2 (mouse)
mASIC2

organism-sequence


PR:Q925H0-1 acid-sensing ion channel 2 isoform 1 (mouse)
mASIC2/iso:1

organism-sequence


PR:Q925H0-2 acid-sensing ion channel 2 isoform 2 (mouse)
mASIC2/iso:2

sequence


PR:000040698 acid-sensing ion channel 2 isoform 1
ASIC2/iso:1

organism-sequence


PR:Q16515-1 acid-sensing ion channel 2 isoform 1 (human)
hASIC2/iso:1

organism-sequence


PR:Q62962-1 acid-sensing ion channel 2 isoform 1 (rat)
rASIC2/iso:1

organism-sequence


PR:Q925H0-1 acid-sensing ion channel 2 isoform 1 (mouse)
mASIC2/iso:1

sequence


PR:000040699 acid-sensing ion channel 2 isoform 2
ASIC2/iso:2

organism-sequence


PR:Q16515-2 acid-sensing ion channel 2 isoform 2 (human)
hASIC2/iso:2

organism-sequence


PR:Q62962-2 acid-sensing ion channel 2 isoform 2 (rat)
rASIC2/iso:2

organism-sequence


PR:Q925H0-2 acid-sensing ion channel 2 isoform 2 (mouse)
mASIC2/iso:2

gene


PR:000003615 acid-sensing ion channel 1
ASIC1

organism-gene


PR:P55926 acid-sensing ion channel 1 (rat)
rASIC1

organism-sequence


PR:P55926-1 acid-sensing ion channel 1 isoform 1 (rat)
rASIC1/iso:1

organism-sequence


PR:P55926-2 acid-sensing ion channel 1 isoform rASIC-beta2 (rat)
rASIC1/iso:rASIC-beta2

organism-sequence


PR:P55926-3 acid-sensing ion channel 1 isoform rASIC1b (rat)
rASIC1/iso:rASIC1b

organism-gene


PR:P78348 acid-sensing ion channel 1 (human)
hASIC1

organism-sequence


PR:P78348-1 acid-sensing ion channel 1 isoform h1 (human)
hASIC1/iso:h1

organism-sequence


PR:P78348-2 acid-sensing ion channel 1 isoform hAsic1a (human)
hASIC1/iso:hAsic1a

organism-sequence


PR:P78348-3 acid-sensing ion channel 1 isoform hAsic1b (human)
hASIC1/iso:hAsic1b

organism-gene


PR:Q1XA76 acid-sensing ion channel 1 (chicken)
chick-ASIC1

organism-gene


PR:Q6NXK8 acid-sensing ion channel 1 (mouse)
mASIC1

organism-sequence


PR:Q6NXK8-1 acid-sensing ion channel 1 isoform 1 (mouse)
mASIC1/iso:1

organism-sequence


PR:Q6NXK8-2 acid-sensing ion channel 1 isoform mAsic1b (mouse)
mASIC1/iso:mAsic1b

organism-gene


PR:Q708S7 acid-sensing ion channel 1A (zebrafish)
z-ASIC1

sequence


PR:000041181 acid-sensing ion channel 1 isoform 1
ASIC1/iso:1

organism-sequence


PR:P55926-1 acid-sensing ion channel 1 isoform 1 (rat)
rASIC1/iso:1

organism-sequence


PR:Q6NXK8-1 acid-sensing ion channel 1 isoform 1 (mouse)
mASIC1/iso:1

gene


PR:000003616 acid-sensing ion channel 3
ASIC3

organism-gene


PR:O35240 acid-sensing ion channel 3 (rat)
rASIC3

organism-gene


PR:Q6X1Y6 acid-sensing ion channel 3 (mouse)
mASIC3

organism-sequence


PR:Q6X1Y6-1 acid-sensing ion channel 3 isoform m1 (mouse)
mASIC3/iso:m1

organism-sequence


PR:Q6X1Y6-2 acid-sensing ion channel 3 isoform m2 (mouse)
mASIC3/iso:m2

organism-gene


PR:Q9UHC3 acid-sensing ion channel 3 (human)
hASIC3

organism-sequence


PR:Q9UHC3-1 acid-sensing ion channel 3 isoform h1 (human)
hASIC3/iso:h1

organism-sequence


PR:Q9UHC3-2 acid-sensing ion channel 3 isoform h2 (human)
hASIC3/iso:h2

organism-sequence


PR:Q9UHC3-3 acid-sensing ion channel 3 isoform h3 (human)
hASIC3/iso:h3

organism-sequence


PR:Q9UHC3-4 acid-sensing ion channel 3 isoform h4 (human)
hASIC3/iso:h4