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Protein Ontology report - cell adhesion molecule CEACAM1 sequence variant CEACAM1a (mouse)
PR:000044466 - http://purl.obolibrary.org/obo/PR_000044466
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza / PAF / GPI
  PRO ID
PR:000044466   
  PRO namecell adhesion molecule CEACAM1 sequence variant CEACAM1a (mouse) 
  Synonyms
PRO-Short-label: EXACT:mCEACAM1a
  Definition"A cell adhesion molecule CEACAM1 (mouse) that is the protein product of allele a of the CEACAM1 gene in mouse. Example: PR:P31809-1." [PRO:CNA, PRO:DAN] 
  PRO Categoryorganism-sequence 
  ParentPR:P31809 cell adhesion molecule CEACAM1 (mouse)
  TaxonNCBITaxon:10090 Mus musculus
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Sequence0                                                  Organism-Sequence 8                                        
         Modification0                                                  Organism-Modification 2                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
organism-sequence



PR:000044466

cell adhesion molecule CEACAM1 sequence variant CEACAM1a (mouse)

mCEACAM1a


"A cell adhesion molecule CEACAM1 (mouse) that is the protein product of allele a of the CEACAM1 gene in mouse. Example: PR:P31809-1." [PRO:CNA, PRO:DAN]

Yes

organism-sequence



PR:P31809-1

CEACAM1a-4L (mouse)

mCEACAM1a/iso:4L


"A cell adhesion molecule CEACAM1 sequence variant CEACAM1a (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P31809-1. This form contains the four copies of the Ig domain and is the version with longer cytoplasmic tail." [PMID:10491101, PMID:11483763, PMID:7628460, PRO:KRC, UniProtKB:P31809]

Yes

organism-sequence



PR:P31809-2

CEACAM1a-4S (mouse)

mCEACAM1a/iso:4S


"A cell adhesion molecule CEACAM1 sequence variant CEACAM1a (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P31809-2. This form contains the four copies of the Ig domain and is the version with shorter cytoplasmic tail." [PMID:10491101, PMID:11483763, PMID:1633107, PMID:7628460, PRO:KRC, UniProtKB:P31809]


organism-sequence



PR:P31809-3

CEACAM1a-2L (mouse)

mCEACAM1a/iso:3


"A cell adhesion molecule CEACAM1 sequence variant CEACAM1a (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P31809-3. This form contains the two copies of the Ig domain and is the version with longer cytoplasmic tail." [PMID:10491101, PMID:11483763, PMID:7628460, PRO:KRC, UniProtKB:P31809]

Yes

organism-sequence



PR:P31809-4

CEACAM1a-2S (mouse)

mCEACAM1a/iso:2S


"A cell adhesion molecule CEACAM1 sequence variant CEACAM1a (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q3LFS8. This form contains the two copies of the Ig domain and is the version with shorter cytoplasmic tail." [PMID:10491101, PMID:11483763, PMID:7628460, PRO:KRC]

Yes

organism-modification



PR:000044462

CEACAM1a-2S, signal peptide removed form (mouse)

mCEACAM1a/iso:2S/SigPep-


"A CEACAM1a-2S (mouse) that has had the signal peptide removed. UniProtKB:P31809-4, 35-278." [PMID:1648219, PRO:DAN, PRO:KRC, UniProtKB:P31809]


organism-modification



PR:000044488

CEACAM1a-2S, signal peptide removed N-glycosylasparagine form (mouse)

mCEACAM1a/iso:2S/SigPep-/NGlycoAsn+


"A CEACAM1a-2S, signal peptide removed form (mouse) that includes at least one N-glycosylasparagine. UniProtKB:P31809-4, 35-278, MOD:00160." [PMID:8380065, PRO:KRC]

Yes

organism-sequence



PR:Q3LFS5

CEACAM1a-4C1 (mouse)

mCEACAM1a/iso:4C1


"A cell adhesion molecule CEACAM1 sequence variant CEACAM1a (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q3LFS5. This form contains the four copies of the Ig domain. This isoform lacks the transmembrane domain." [PMID:19358828, PRO:KRC, UniProtKB:P31809]


organism-sequence



PR:Q3LFS6

CEACAM1a-2C1 (mouse)

mCEACAM1a/iso:2C1


"A cell adhesion molecule CEACAM1 sequence variant CEACAM1a (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q3LFS6. This form contains the two copies of the Ig domain. This isoform lacks the transmembrane domain." [PMID:19358828, PRO:KRC, UniProtKB:P31809]


organism-sequence



PR:Q3LFS7

CEACAM1a-2 (mouse)

mCEACAM1a/iso:2


"A cell adhesion molecule CEACAM1 sequence variant CEACAM1a (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q3LFS7." [PMID:19358828, PRO:KRC, UniProtKB:P31809]


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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000044466 mCEACAM1a
Example: PR:P31809-1
acts_upstream_of_or_withinGO:0044794 host-mediated activation of viral process MGI_ref:1098064; PMID:9343248
PR:000044488 mCEACAM1a/iso:2S/SigPep-/NGlycoAsn+
UniProtKB:P31809-4, 35-278, MOD:00160
enablesGO:0046790 virion binding MGI_ref:3053174; PMID:8380065
PR:P31809-1 mCEACAM1a/iso:4L
This form contains the four copies of the Ig domain and is the version with longer cytoplasmic tail
acts_upstream_of_or_withinGO:0032703 negative regulation of interleukin-2 production MGI_ref:3693042; PMID:17081782
GO:0042130 negative regulation of T cell proliferation MGI_ref:3693042; PMID:17081782
PR:P31809-3 mCEACAM1a/iso:3
This form contains the two copies of the Ig domain and is the version with longer cytoplasmic tail
acts_upstream_of_or_withinGO:0032703 negative regulation of interleukin-2 production MGI_ref:3693042; PMID:17081782
GO:0046329 negative regulation of JNK cascade MGI_ref:3693042; PMID:17081782
PR:P31809-4 mCEACAM1a/iso:2S
This form contains the two copies of the Ig domain and is the version with shorter cytoplasmic tail
acts_upstream_of_or_withinGO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules MGI_ref:5503958; PMID:10491101
located_inGO:0009897 external side of plasma membrane MGI_ref:81180; PMID:8896983
GO:0009897 external side of plasma membrane MGI_ref:81180; PMID:8896983