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PRO ID
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| PRO name | tyrosine-protein kinase BTK phosphorylated 1 (mouse) |
| Synonyms | | PRO-Short-label: | EXACT: | mBTK/Phos:1 | | PRO-proteoform-std: | EXACT: | UniProtKB:P35991, Tyr-223/Tyr-551, MOD:00048 | | Other: | RELATED: | active BTK |
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| Definition | "A tyrosine-protein kinase BTK (mouse) that is phosphorylated on two Tyr residues. Site 1 is a Tyr within the Src homology type 1 (SH1) domain and is transphosphorylated by a Src family tyrosine kinase. Site 2 is an autophosphorylation site within the Btk SH3 domain. UniProtKB:P35991, Tyr-223/Tyr-551, MOD:00048." [PMID:9326643] |
| Comment | Note: Activation of Btk correlates with an increase in the phosphorylation of two regulatory Btk tyrosine residues. |
| PRO Category | organism-modification |
| Parent | PR:000037070 phosphoprotein
PR:P35991 tyrosine-protein kinase BTK (mouse)
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| Taxon | NCBITaxon:10090 Mus musculus |
Term Hierarchy
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