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Protein Ontology report - LPS:CD14 complex
PR:000037465 - http://purl.obolibrary.org/obo/PR_000037465
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000037465   
  PRO nameLPS:CD14 complex 
  Synonyms
PRO-Short-label: EXACT:LPS:CD14
  Definition"A macromolecular complex that contains CD14 bound to lipopolysaccharides (LPS)." [PMID:18761368] 
  PRO Categorycomplex 
  ParentG0032991 protein-containing complex
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Complex4                                                  Organism-Complex 5                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

Comp. In Complex?
complex


PR:000037465
LPS:CD14 complex
LPS:CD14
"A macromolecular complex that contains CD14 bound to lipopolysaccharides (LPS)." [PMID:18761368]

complex


PR:000025493
LPS:GPI-anchored CD14 complex
LPS:mCD14
"An LPS:CD14 complex that contains the membrane bound form of CD14 bound to lipopolysaccharides (LPS)." [PMID:7539760]

organism-complex


PR:000037464
LPS:GPI-anchored CD14 complex (human)
h-LPS:mCD14
"An LPS:GPI-anchored CD14 complex whose components are encoded in the genome of human." [Reactome:R-HSA-166034]
Yes
organism-complex


PR:000037468
LPS:GPI-anchored CD14 complex (mouse)
m-LPS:sCD14
"An LPS:GPI-anchored CD14 complex whose components are encoded in the genome of mouse." [PMID:10601848]

complex


PR:000029989
LPS:secreted CD14 complex
LPS:sCD14
"An LPS:CD14 complex that contains a soluble form of CD14 bound to lipopolysaccharides (LPS)." [PRO:DAN]

complex


PR:000025494
LPS:secreted CD14 alpha
LPS:sCD14alpha
"An LPS:secreted CD14 complex that contains the low M(r) soluble form of CD14 bound to lipopolysaccharides (LPS)." [PMID:16861002, PMID:7681988, PRO:CNA, PRO:DAN]

organism-complex


PR:000037463
LPS:secreted CD14 alpha (human)
h-LPS:sCD14alpha
"An LPS:secreted CD14 alpha whose components are encoded in the genome of human." [Reactome:R-HSA-166026]
Yes
organism-complex


PR:000037467
LPS:secreted CD14 complex (mouse)
m-LPS:sCD14
"An LPS:secreted CD14 complex whose components are encoded in the genome of mouse." [PMID:10601848, PMID:18606699]

organism-complex


PR:000037466
LPS:transmembrane CD14 complex (chicken)
LPS:CD14
"An LPS:CD14 complex in chicken in which the CD14 molecule is the transmembrane form." [ECO:0000305, PMID:18761368, PMID:24034933, PRO:CNA]
Yes
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000037463 h-LPS:sCD14alpha acts_upstream_of_or_withinGO:0034142 toll-like receptor 4 signaling pathway Reactome:REACT_6894
located_inGO:0005615 extracellular space Reactome:REACT_7856
PR:000037464 h-LPS:mCD14 acts_upstream_of_or_withinGO:0034142 toll-like receptor 4 signaling pathway Reactome:REACT_6894
located_inGO:0005886 plasma membrane Reactome:REACT_7856
PR:000037466 LPS:CD14 acts_upstream_of_or_withinGO:0045429 positive regulation of nitric oxide biosynthetic process PMID:24034933
GO:0051607 defense response to virus PMID:24034933
located_inGO:0009986 cell surface PMID:18761368; PMID:24034933