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Protein Ontology report - double-stranded RNA-specific adenosine deaminase isoform 1
PR:000037168 - http://purl.obolibrary.org/obo/PR_000037168
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000037168   
  PRO namedouble-stranded RNA-specific adenosine deaminase isoform 1 
  Synonyms
PRO-Short-label: EXACT:ADAR/iso:1
Other: EXACT:ADAR p150
  Definition"A double-stranded RNA-specific adenosine deaminase that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q99MU3-1 or a 1:1 ortholog thereof. This form is produced by alternative promoter usage." [PMID:10200312, PRO:CNA] 
  PRO Categorysequence 
  ParentPR:000003745 double-stranded RNA-specific adenosine deaminase
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Sequence1                                                  Organism-Sequence 2                                        
         Modification0                                                  Organism-Modification 0                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

Comp. In Complex?
sequence


PR:000037168 double-stranded RNA-specific adenosine deaminase isoform 1
ADAR/iso:1

organism-sequence


PR:P55265-1 double-stranded RNA-specific adenosine deaminase isoform 1 (human)
hADAR/iso:1

organism-sequence


PR:Q99MU3-1 double-stranded RNA-specific adenosine deaminase isoform 1 (mouse)
mADAR/iso:1
Yes
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Functional Annotation (GO-centric view) Switch to PRO Centric View     

Biological Process GO Term
Protein Forms & Complexes
Evidence
GO:0001701 in utero embryonic developmentPR:Q99MU3-1 mADAR/iso:1 MGI_ref:4939544; PMID:21173229
GO:0045071 negative regulation of viral genome replicationPR:Q99MU3-1 mADAR/iso:1 MGI_ref:4939544; PMID:21173229
GO:0051607 defense response to virusPR:Q99MU3-1 mADAR/iso:1 MGI_ref:4939544; PMID:21173229

Molecular Function GO Term
Protein Forms & Complexes
Evidence
GO:0003726 double-stranded RNA adenosine deaminase activityPR:Q99MU3-1 mADAR/iso:1 MGI_ref:5515381; PMID:12954622

Cellular Location GO Term
Protein Forms & Complexes
Evidence
GO:0005737 cytoplasmPR:Q99MU3-1 mADAR/iso:1 MGI_ref:5515381; PMID:12954622