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RACE-PRO
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Protein Ontology report - NS1 dimer
PR:000037002 -
http://purl.obolibrary.org/obo/PR_000037002
Protein Forms
Annotations
Ontology Information
Show OBO stanza
/
PAF
PRO ID
PR:000037002
PRO name
NS1 dimer
Definition
"A protein-containing complex that is a dimer of NS1." [PRO:ES]
Comment
Requested by=IDODEN. Dimerization is required for NS1 transport through the Golgi system, where the glycans attached to the Asn-130 sites of the dimer and are modified to complex sugars; this is followed by transport to the plasma membrane, where a portion of NS1 is released from the cell. [
PMID:15592895
, PRO:ES].
PRO Category
complex
Parent
G0032991
protein-containing complex
Terms by PRO Category
Organism-Independent
Organism-Specific
Category
Number of Terms
Category
Number of Terms
Complex
3
Organism-Complex
0
Term Hierarchy
Visualization
DAG:
OLS:
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Protein Forms
Switch to
Compact View
Category
PRO ID
Name
Short Name
Definition
Ann.
Has Annotation?
Comp.
In Complex?
complex
PR:000037002
NS1 dimer
DenV-NS1/sugar(-)
"A protein-containing complex that is a dimer of NS1." [PRO:ES]
Yes
complex
PR:000037003
NS1 dimer, with complex sugar attached
DenV-NS1/sugar(-)
"An NS1 dimer that has glycans attached to the Asn-130 site which are modified to complex sugars." [PMID:15592895, PMID:21429549, PRO:ES]
complex
PR:000037004
NS1 dimer, without complex sugar unattached
DenV-NS1/sugar(-)
"An NS1 dimer that has glycans attached to the Asn-130 site which are not modified to complex sugars." [PMID:15592895, PMID:21429549, PRO:ES]
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Functional Annotation (PRO-centric view)
Switch to
GO Centric View
PRO Term
GO Annotation
Evidence
PR:000037002
DenV-NS1/sugar(-)
acts_upstream_of_or_within
GO:0019079
viral genome replication
PMID:8659120
GO:0097281
immune complex formation
PMID:8659120
located_in
GO:0019034
viral replication complex
PMID:8659120
