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Protein Ontology report - NS5
PR:000036835 - http://purl.obolibrary.org/obo/PR_000036835
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000036835   
  PRO nameNS5 
  Synonyms
PRO-Short-label: EXACT:DenV-NS5
Other: EXACT:Non-structural protein 5 | RdRp NS5 | RNA directed RNA polymerase NS5
  Definition"A dengue virus genome polyprotein proteolytic cleavage product that is a large non-structural protein encoded by the dengue virus RNA genome containing a methyltransferase (MTase) domain and an RNA dependent RNA polymerase (POL) domain that possesses a capping enzyme." [PMID:22022449, PRO:ES] 
  CommentRequested by=IDODEN. 
  PRO Categorymodification 
  ParentPR:000036818 dengue virus genome polyprotein proteolytic cleavage product
PR:000036834 precursor of NS5
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Modification1                                                  Organism-Modification 1                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

Comp. In Complex?
modification


PR:000036835 NS5
DenV-NS5

organism-modification


PR:000044768 NS5 (Dengue virus 2 Thailand/NGS-C/1944)
NS5 (DEN2N)
Yes
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Functional Annotation (GO-centric view) Switch to PRO Centric View     

Biological Process GO Term
Protein Forms & Complexes
Evidence
GO:0001510 RNA methylationPR:000044768 NS5 (DEN2N) PMID:21810535
GO:0019079 viral genome replicationPR:000044768 NS5 (DEN2N) PMID:21810535
GO:0042783 symbiont-mediated evasion of host immune responsePR:000044768 NS5 (DEN2N) PMID:21810535

Molecular Function GO Term
Protein Forms & Complexes
Evidence
GO:0003968 RNA-directed RNA polymerase activityPR:000044768 NS5 (DEN2N) PMID:21810535
GO:0008168 methyltransferase activityPR:000044768 NS5 (DEN2N) PMID:21810535
GO:0070568 guanylyltransferase activityPR:000044768 NS5 (DEN2N) PMID:23408612

Cellular Location GO Term
Protein Forms & Complexes
Evidence
GO:0019034 viral replication complexPR:000044768 NS5 (DEN2N) PMID:21810535