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Protein Ontology report - interferon regulatory factor 8 isoform 1
PR:000035704 - http://purl.obolibrary.org/obo/PR_000035704
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000035704   
  PRO nameinterferon regulatory factor 8 isoform 1 
  Synonyms
PRO-Short-label: EXACT:IRF8/iso:1
Other: EXACT:IRF8 isoform 1
  Definition"An interferon regulatory factor 8 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P23611-1 or a 1:1 ortholog thereof." [PMID:22942423, PRO:HJD] 
  PRO Categorysequence 
  ParentPR:000002050 interferon regulatory factor 8
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Sequence1                                                  Organism-Sequence 1                                        
         Modification2                                                  Organism-Modification 2                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

Comp. In Complex?
sequence


PR:000035704
interferon regulatory factor 8 isoform 1
IRF8/iso:1
"An interferon regulatory factor 8 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P23611-1 or a 1:1 ortholog thereof." [PMID:22942423, PRO:HJD]

organism-sequence


PR:P23611-1
interferon regulatory factor 8 isoform 1 (mouse)
mIRF8/iso:1
"An interferon regulatory factor 8 isoform 1 that is encoded in the genome of mouse." [PMID:2111015, PRO:HJD]

organism-modification


PR:000035707
interferon regulatory factor 8 isoform 1 sumoylated 1 (mouse)
mIRF8/iso:1/Sumo:1
"An interferon regulatory factor 8 isoform 1 sumoylated 1 in mouse. UniProtKB:P23611-1, Lys-310, MOD:01149." [PMID:22942423, PRO:HJD]
Yes
organism-modification


PR:000035709
interferon regulatory factor 8 isoform 1 unsumoylated form (mouse)
mIRF8/iso:1/SumoRes-
"An interferon regulatory factor 8 isoform 1 unsumoylated form in mouse." [PMID:22942423, PRO:HJD]
Yes
modification


PR:000035706
interferon regulatory factor 8 isoform 1 sumoylated 1
IRF8/iso:1/Sumo:1
"An interferon regulatory factor 8 isoform 1 that has been post-translationally modified to have a glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO) with SUMO3. Example: UniProtKB:P23611-1, Lys-310, MOD:01149." [PMID:22942423, PRO:HJD]

organism-modification


PR:000035707
interferon regulatory factor 8 isoform 1 sumoylated 1 (mouse)
mIRF8/iso:1/Sumo:1
"An interferon regulatory factor 8 isoform 1 sumoylated 1 in mouse. UniProtKB:P23611-1, Lys-310, MOD:01149." [PMID:22942423, PRO:HJD]
Yes
modification


PR:000035708
interferon regulatory factor 8 isoform 1 unsumoylated form
IRF8/iso:1/SumoRes-
"An interferon regulatory factor 8 isoform 1 that lacks sumoylated residues." [PMID:22942423, PRO:HJD]

organism-modification


PR:000035709
interferon regulatory factor 8 isoform 1 unsumoylated form (mouse)
mIRF8/iso:1/SumoRes-
"An interferon regulatory factor 8 isoform 1 unsumoylated form in mouse." [PMID:22942423, PRO:HJD]
Yes
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000035707 mIRF8/iso:1/Sumo:1
UniProtKB:P23611-1, Lys-310, MOD:01149		 acts_upstream_of_or_withinNOT GO:0060261 positive regulation of transcription initiation by RNA polymerase II MGI_ref:5448615; PMID:22942423
located_inGO:0005634 nucleus MGI_ref:5448615; PMID:22942423
PR:000035709 mIRF8/iso:1/SumoRes- acts_upstream_of_or_withinGO:0060261 positive regulation of transcription initiation by RNA polymerase II MGI_ref:5448615; PMID:22942423
located_inGO:0005634 nucleus MGI_ref:5448615; PMID:22942423