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Protein Ontology report - mitotic checkpoint serine/threonine-protein kinase BUB1 beta phosphorylated 4
PR:000035434 - http://purl.obolibrary.org/obo/PR_000035434
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000035434   
  PRO namemitotic checkpoint serine/threonine-protein kinase BUB1 beta phosphorylated 4 
  Synonyms
PRO-Short-label: EXACT:BUB1B/Phos:4
Other: RELATED:BUBR1 phosphorylated
  Definition"A mitotic checkpoint serine/threonine-protein kinase BUB1 beta that has been phosphorylated on residues at positions equivalent to Ser-543, Ser-670, and Ser-1043 of the amino acid sequence represented by UniProtKB:O60566-1. Additional Ser residues could be phosphorylated. Example: UniProtKB:O60566-1, Ser-543/Ser-670/Ser-1043, MOD:00046." [PMID:19015317, PMID:20016069, PRO:KER] 
  PRO Categorymodification 
  ParentPR:000004855 mitotic checkpoint serine/threonine-protein kinase BUB1 beta
PR:000037070 phosphoprotein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Modification1                                                  Organism-Modification 1                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

Comp. In Complex?
modification


PR:000035434
mitotic checkpoint serine/threonine-protein kinase BUB1 beta phosphorylated 4
BUB1B/Phos:4
"A mitotic checkpoint serine/threonine-protein kinase BUB1 beta that has been phosphorylated on residues at positions equivalent to Ser-543, Ser-670, and Ser-1043 of the amino acid sequence represented by UniProtKB:O60566-1. Additional Ser residues could be phosphorylated. Example: UniProtKB:O60566-1, Ser-543/Ser-670/Ser-1043, MOD:00046." [PMID:19015317, PMID:20016069, PRO:KER]

organism-modification


PR:000035435
mitotic checkpoint serine/threonine-protein kinase BUB1 beta phosphorylated 4 (human)
hBUB1B/Phos:4
"A mitotic checkpoint serine/threonine-protein kinase BUB1 beta phosphorylated 4 in human. This phosphorylated form is observed in prophase, prometaphase, metaphase, anaphase, spindle depolymerization (nocodazole). This form is not observed when there is a lack of kinetochore tension (taxol). Ser-435, Ser-574 and Ser-720 could also be phosphorylated. Example: UniProtKB:O60566-1, Ser-543/Ser-670/Ser-1043, MOD:00046." [PMID:19015317, PMID:20016069, PRO:KER]
Yes
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000035435 hBUB1B/Phos:4
Example: UniProtKB:O60566-1, Ser-543/Ser-670/Ser-1043, MOD:00046		 acts_upstream_of_or_withinincreased GO:0008608 attachment of spindle microtubules to kinetochore relative to PR:000035373 hBUB1B/PhosRes- PMID:19015317; PMID:20016069
increased GO:0051310 metaphase chromosome alignment relative to PR:000035373 hBUB1B/PhosRes- PMID:20016069
located_inGO:0000776 kinetochore PMID:19015317