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Protein Ontology report - catenin beta-1 isoform 1 phosphorylated 1 (human) PR:000030192 - http://purl.obolibrary.org/obo/PR_000030192        Annotations       Ontology Information Show OBO stanza / PAF / GPI   PRO ID PR:000030192      PRO name catenin beta-1 isoform 1 phosphorylated 1 (human)    Synonyms PRO-Short-label: EXACT: hCTNNB1/iso:1/Phos:1 PRO-proteoform-std: EXACT: UniProtKB:P35222-1, Ser-663/Ser-675, MOD:00046   Definition "A catenin beta-1 isoform 1 phosphorylated 1 in human. Phosphorylation at Ser-663 is found in many human colon cancer cells and tissues, which display a high PAK1 activity, or in response to Wnt3a stimulation. Ser-675 can be phosphorylated by either PAK1 or PKA. UniProtKB:P35222-1, Ser-663/Ser-675, MOD:00046." [PMID:22369945, PRO:IC]    Comment Kinase=("PAK1"; PR:000035776; Ser-663/Ser-675). Kinase=("PKA"; PR:000029188; Ser-675).    PRO Category organism-modification    Parent PR:000030191 catenin beta-1 isoform 1 phosphorylated 1 PR:P35222 catenin beta-1 (human)   Taxon NCBITaxon:9606 Homo sapiens   Term Hierarchy   Visualization DAG: OLS: Back to top Functional Annotation (PRO-centric view) Switch to GO Centric View    PRO Term GO Annotation Evidence PR:000030192 hCTNNB1/iso:1/Phos:1 UniProtKB:P35222-1, Ser-663/Ser-675, MOD:00046 acts_upstream_of_or_within GO:0016055 Wnt signaling pathway PMID:22369945 enables increased GO:0003713 transcription coactivator activity relative to PR:000002862 CTNNB1/iso:1/UnMod PMID:22369945